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Publikationer i urvalet

7 träffar

Bibliografisk träff 2024-05-16

WLB-87848, a Selective σ1 Receptor Agonist, with an Unusually Positioned NH Group as Positive Ionizable Moiety and Showing Neuroprotective Activity.

Christmann U, Garriga L, Llorente AV, Díaz JL, Pascual R, Bordas M, Dordal A, Porras M, Yeste S, Reinoso RF, Vela JM, Almansa C.

J Med Chem · journal article · DOI 10.1021/acs.jmedchem.4c00288

Bibliografisk träff 2023-01-26

Novel S1R agonists counteracting NMDA excitotoxicity and oxidative stress: A step forward in the discovery of neuroprotective agents.

Linciano P, Sorbi C, Rossino G, Rossi D, Marsala A, Denora N, Bedeschi M, Marino N, Miserocchi G, Dondio G, Peviani M, Tesei A, Collina S, Franchini S.

Eur J Med Chem · journal article · DOI 10.1016/j.ejmech.2023.115163

Bibliografisk träff 2022-09-26

Structure-activity relationships of mixed σ1R/σ2R ligands with antiproliferative and anticancer effects.

Fallica AN, Ciaffaglione V, Modica MN, Pittalà V, Salerno L, Amata E, Marrazzo A, Romeo G, Intagliata S.

Bioorg Med Chem · research support, non-u.s. gov't; review; journal article · DOI 10.1016/j.bmc.2022.117032

Bibliografisk träff 2020-10-28

Small Molecules Selectively Targeting Sigma-1 Receptor for the Treatment of Neurological Diseases.

Ye N, Qin W, Tian S, Xu Q, Wold EA, Zhou J, Zhen XC.

J Med Chem · research support, non-u.s. gov't; review; journal article; research support, n.i.h., extramural · DOI 10.1021/acs.jmedchem.0c01192

Bibliografisk träff 2013-01-05

Synthesis, pharmacological evaluation and QSAR modeling of mono-substituted 4-phenylpiperidines and 4-phenylpiperazines.

Pettersson F, Svensson P, Waters S, Waters N, Sonesson C.

Eur J Med Chem · journal article · DOI 10.1016/j.ejmech.2012.12.031

Bibliografisk träff 2012-10-17

Systematic in vivo screening of a series of 1-propyl-4-arylpiperidines against dopaminergic and serotonergic properties in rat brain: a scaffold-jumping approach.

Mattsson C, Andreasson T, Waters N, Sonesson C.

J Med Chem · journal article · DOI 10.1021/jm300975f

Bibliografisk träff 2010-03-01

Synthesis and evaluation of a set of 4-phenylpiperidines and 4-phenylpiperazines as D2 receptor ligands and the discovery of the dopaminergic stabilizer 4-[3-(methylsulfonyl)phenyl]-1-propylpiperidine (huntexil, pridopidine, ACR16).

Pettersson F, Pontén H, Waters N, Waters S, Sonesson C.

J Med Chem · journal article · DOI 10.1021/jm901689v

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Publikationer i urvalet

WLB-87848, a Selective σ<sub>1</sub> Receptor Agonist, with an Unusually Positioned NH Group as Positive Ionizable Moiety and Showing Neuroprotective Activity.

Novel S1R agonists counteracting NMDA excitotoxicity and oxidative stress: A step forward in the discovery of neuroprotective agents.

Structure-activity relationships of mixed σ<sub>1</sub>R/σ<sub>2</sub>R ligands with antiproliferative and anticancer effects.

Small Molecules Selectively Targeting Sigma-1 Receptor for the Treatment of Neurological Diseases.

Synthesis, pharmacological evaluation and QSAR modeling of mono-substituted 4-phenylpiperidines and 4-phenylpiperazines.

Systematic in vivo screening of a series of 1-propyl-4-arylpiperidines against dopaminergic and serotonergic properties in rat brain: a scaffold-jumping approach.

Synthesis and evaluation of a set of 4-phenylpiperidines and 4-phenylpiperazines as D2 receptor ligands and the discovery of the dopaminergic stabilizer 4-[3-(methylsulfonyl)phenyl]-1-propylpiperidine (huntexil, pridopidine, ACR16).