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Publikationer i urvalet

9 träffar

Bibliografisk träff 2022-10-29

Identification of 1,2,3-triazolium salt-based inhibitors of Leishmania infantum trypanothione disulfide reductase with enhanced antileishmanial potency in cellulo and increased selectivity.

de Lucio H, Revuelto A, Carriles AA, de Castro S, García-González S, García-Soriano JC, Alcón-Calderón M, Sánchez-Murcia PA, Hermoso JA, Gago F, Camarasa MJ, Jiménez-Ruiz A, Velázquez S.

Eur J Med Chem · journal article · DOI 10.1016/j.ejmech.2022.114878

Bibliografisk träff 2021-02-15

Generation of reactive oxygen species is the primary mode of action and cause of survivin suppression by sepantronium bromide (YM155).

Wani TH, Chowdhury G, Chakrabarty A.

RSC Med Chem · research-article; journal article · DOI 10.1039/d0md00383b

Bibliografisk träff 2020-08-28

A Novel Redox Modulator Induces a GPX4-Mediated Cell Death That Is Dependent on Iron and Reactive Oxygen Species.

Hu S, Sechi M, Singh PK, Dai L, McCann S, Sun D, Ljungman M, Neamati N.

J Med Chem · research support, non-u.s. gov't; research-article; journal article; research support, n.i.h., extramural · DOI 10.1021/acs.jmedchem.0c01016

Bibliografisk träff 2014-03-21

Buthionine sulfoximine diverts the melanogenesis pathway toward the production of more soluble and degradable pigments.

Galván I, Wakamatsu K, Alonso-Alvarez C, Solano F.

Bioorg Med Chem Lett · research support, non-u.s. gov't; journal article · DOI 10.1016/j.bmcl.2014.03.031

Tillbakadragen publikation 2011-06-24

Collateral sensitivity of multidrug-resistant cells to the orphan drug tiopronin.

Goldsborough AS, Handley MD, Dulcey AE, Pluchino KM, Kannan P, Brimacombe KR, Hall MD, Griffiths G, Gottesman MM.

J Med Chem · retracted publication; research support, n.i.h., intramural; research-article; journal article · DOI 10.1021/jm2001663

Bibliografisk träff 2009-09-06

Genetic mapping of targets mediating differential chemical phenotypes in Plasmodium falciparum.

Yuan J, Johnson RL, Huang R, Wichterman J, Jiang H, Hayton K, Fidock DA, Wellems TE, Inglese J, Austin CP, Su XZ.

Nat Chem Biol · research support, n.i.h., intramural; research-article; journal article; research support, n.i.h., extramural · DOI 10.1038/nchembio.215

Bibliografisk träff 2008-03-10

Buthionine sulfoximine has anti-Trypanosoma cruzi activity in a murine model of acute Chagas' disease and enhances the efficacy of nifurtimox.

Faúndez M, López-Muñoz R, Torres G, Morello A, Ferreira J, Kemmerling U, Orellana M, Maya JD.

Antimicrob Agents Chemother · research support, non-u.s. gov't; research-article; journal article · DOI 10.1128/aac.01454-07

Bibliografisk träff 2007-07-18

Targeting thioredoxin reductase is a basis for cancer therapy by arsenic trioxide.

Lu J, Chew EH, Holmgren A.

Proc Natl Acad Sci U S A · research support, non-u.s. gov't; research-article; journal article · DOI 10.1073/pnas.0701549104

Bibliografisk träff 2007-04-08

Chemical genetics reveals a complex functional ground state of neural stem cells.

Diamandis P, Wildenhain J, Clarke ID, Sacher AG, Graham J, Bellows DS, Ling EK, Ward RJ, Jamieson LG, Tyers M, Dirks PB.

Nat Chem Biol · research support, non-u.s. gov't; journal article · DOI 10.1038/nchembio873