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Publikationer i urvalet

12 träffar

Bibliografisk träff 2013-02-26

Lovastatin-induced decrease of intracellular cholesterol level attenuates fibroblast-to-myofibroblast transition in bronchial fibroblasts derived from asthmatic patients.

Michalik M, Soczek E, Kosińska M, Rak M, Wójcik KA, Lasota S, Pierzchalska M, Czyż J, Madeja Z.

Eur J Pharmacol · research support, non-u.s. gov't; journal article · DOI 10.1016/j.ejphar.2013.02.023

Bibliografisk träff 2012-04-03

Binding modes of zaragozic acid A to human squalene synthase and staphylococcal dehydrosqualene synthase.

Liu CI, Jeng WY, Chang WJ, Ko TP, Wang AH.

J Biol Chem · research support, non-u.s. gov't; research-article; journal article · DOI 10.1074/jbc.m112.351254

Bibliografisk träff 2010-12-23

Improvement of dolichol-linked oligosaccharide biosynthesis by the squalene synthase inhibitor zaragozic acid.

Haeuptle MA, Welti M, Troxler H, Hülsmeier AJ, Imbach T, Hennet T.

J Biol Chem · research support, non-u.s. gov't; research-article; journal article · DOI 10.1074/jbc.m110.165795

Bibliografisk träff 2010-08-16

Cloning, overexpression and characterization of Leishmania donovani squalene synthase.

Bhargava P, Kumar K, Chaudhaery SS, Saxena AK, Roy U.

FEMS Microbiol Lett · research support, non-u.s. gov't; journal article · DOI 10.1111/j.1574-6968.2010.02071.x

Bibliografisk träff 2002-11-01

Squalestatin 1-inducible expression of rat CYP2B: evidence that an endogenous isoprenoid is an activator of the constitutive androstane receptor.

Kocarek TA, Mercer-Haines NA.

Mol Pharmacol · research support, u.s. gov't, p.h.s.; journal article · DOI 10.1124/mol.62.5.1177

Bibliografisk träff 2000-09-01

A symmetry-based formal synthesis of zaragozic acid A.

Freeman-Cook KD, Halcomb RL.

J Org Chem · research support, u.s. gov't, p.h.s.; research support, non-u.s. gov't; research support, u.s. gov't, non-p.h.s.; journal article · DOI 10.1021/jo000665j

Bibliografisk träff 1998-09-01

Regulation of rat hepatic cytochrome P450 expression by sterol biosynthesis inhibition: inhibitors of squalene synthase are potent inducers of CYP2B expression in primary cultured rat hepatocytes and rat liver.

Kocarek TA, Kraniak JM, Reddy AB.

Mol Pharmacol · research support, u.s. gov't, p.h.s.; journal article · DOI 10.1124/mol.54.3.474

Bibliografisk träff 1998-07-01

Massive production of farnesol-derived dicarboxylic acids in mice treated with the squalene synthase inhibitor zaragozic acid A.

Vaidya S, Bostedor R, Kurtz MM, Bergstrom JD, Bansal VS.

Arch Biochem Biophys · journal article · DOI 10.1006/abbi.1998.0704

Bibliografisk träff 1997-04-01

Farnesol-derived dicarboxylic acids in the urine of animals treated with zaragozic acid A or with farnesol.

Bostedor RG, Karkas JD, Arison BH, Bansal VS, Vaidya S, Germershausen JI, Kurtz MM, Bergstrom JD.

J Biol Chem · research support, non-u.s. gov't; journal article · DOI 10.1074/jbc.272.14.9197

Bibliografisk träff 1994-12-01

Effect of squalestatin 1 on the biosynthesis of the mevalonate pathway lipids.

Thelin A, Peterson E, Hutson JL, McCarthy AD, Ericsson J, Dallner G.

Biochim Biophys Acta · research support, non-u.s. gov't; journal article · DOI 10.1016/0005-2760(94)90049-3

Bibliografisk träff 1994-11-01

The preparation of zaragozic acid A analogues by directed biosynthesis.

Chen TS, Petuch B, MacConnell J, White R, Dezeny G, Arison B, Bergstrom JD, Colwell L, Huang L, Monaghan RL.

J Antibiot (Tokyo) · journal article · DOI 10.7164/antibiotics.47.1290

Bibliografisk träff 1992-06-01

Squalestatin 1, a potent inhibitor of squalene synthase, which lowers serum cholesterol in vivo.

Baxter A, Fitzgerald BJ, Hutson JL, McCarthy AD, Motteram JM, Ross BC, Sapra M, Snowden MA, Watson NS, Williams RJ.

J Biol Chem · journal article · DOI 10.1016/s0021-9258(19)49754-8