Inhibition of Mycoplasma pneumoniae growth by FDA-approved anticancer and antiviral nucleoside and nucleobase analogs.
Sun R, Wang L.
BMC Microbiol · research support, non-u.s. gov't; research-article; journal article · DOI 10.1186/1471-2180-13-184 PUBLIKATIONSREGISTRET
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14 träffarLigand-directed acid-sensitive amidophosphate 5-trifluoromethyl-2'-deoxyuridine conjugate as a potential theranostic agent.
Godovikova TS, Lisitskiy VA, Antonova NM, Popova TV, Zakharova OD, Chubarov AS, Koptyug IV, Sagdeev RZ, Kaptein R, Akulov AE, Kaledin VI, Nikolin VP, Baiborodin SI, Koroleva LS, Silnikov VN.
Bioconjug Chem · research support, non-u.s. gov't; journal article · DOI 10.1021/bc3006072Acyclovir-resistant herpetic keratitis in a solid-organ transplant recipient on systemic immunosuppression.
Turner LD, Beckingsale P.
Clin Ophthalmol · journal article; case reports; case-report · DOI 10.2147/opth.s39113Selective anti-herpesvirus agents.
De Clercq E.
Antivir Chem Chemother · review; journal article · DOI 10.3851/imp2533Phase I study of TAS-102 treatment in Japanese patients with advanced solid tumours.
Doi T, Ohtsu A, Yoshino T, Boku N, Onozawa Y, Fukutomi A, Hironaka S, Koizumi W, Sasaki T.
Br J Cancer · research support, non-u.s. gov't; research-article; clinical trial, phase i; journal article · DOI 10.1038/bjc.2012.274Pan-pathway based interaction profiling of FDA-approved nucleoside and nucleobase analogs with enzymes of the human nucleotide metabolism.
Egeblad L, Welin M, Flodin S, Gräslund S, Wang L, Balzarini J, Eriksson S, Nordlund P.
PLoS One · research support, non-u.s. gov't; research-article; journal article · DOI 10.1371/journal.pone.0037724Ganciclovir ophthalmic gel 0.15%: safety and efficacy of a new treatment for herpes simplex keratitis.
Kaufman HE, Haw WH.
Curr Eye Res · review; journal article · DOI 10.3109/02713683.2012.692846Involvement of concentrative nucleoside transporter 1 in intestinal absorption of trifluorothymidine, a novel antitumor nucleoside, in rats.
Okayama T, Yoshisue K, Kuwata K, Komuro M, Ohta S, Nagayama S.
J Pharmacol Exp Ther · journal article · DOI 10.1124/jpet.111.186296Mode of action of trifluorothymidine (TFT) against DNA replication and repair enzymes.
Suzuki N, Emura T, Fukushima M.
Int J Oncol · journal article · DOI 10.3892/ijo.2011.1003Trifluorothymidine exhibits potent antitumor activity via the induction of DNA double-strand breaks.
Suzuki N, Nakagawa F, Nukatsuka M, Fukushima M.
Exp Ther Med · research-article; journal article · DOI 10.3892/etm.2011.244In vitro synergism of trifluorothymidine and ganciclovir against HSV-1.
Hobden JA, Kumar M, Kaufman HE, Clement C, Varnell ED, Bhattacharjee PS, Hill JM.
Invest Ophthalmol Vis Sci · research support, non-u.s. gov't; research-article; journal article; research support, n.i.h., extramural · DOI 10.1167/iovs.10-5671Evaluation of therapeutic interventions for vaccinia virus keratitis.
Altmann S, Brandt CR, Murphy CJ, Patnaikuni R, Takla T, Toomey M, Nesbit B, McIntyre K, Covert J, Dubielzig R, Leatherberry G, Adkins E, Kodihalli S.
J Infect Dis · comparative study; research support, u.s. gov't, p.h.s.; research-article; journal article; research support, n.i.h., extramural · DOI 10.1093/infdis/jiq103Differential activation of cell death and autophagy results in an increased cytotoxic potential for trifluorothymidine compared to 5-fluorouracil in colon cancer cells.
Bijnsdorp IV, Peters GJ, Temmink OH, Fukushima M, Kruyt FA.
Int J Cancer · comparative study; research support, non-u.s. gov't; journal article · DOI 10.1002/ijc.24943Molecular mechanism underlying the synergistic interaction between trifluorothymidine and the epidermal growth factor receptor inhibitor erlotinib in human colorectal cancer cell lines.
Bijnsdorp IV, Kruyt FA, Fukushima M, Smid K, Gokoel S, Peters GJ.
Cancer Sci · research support, non-u.s. gov't; journal article · DOI 10.1111/j.1349-7006.2009.01375.x