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Publikationer i urvalet

8 träffar

Bibliografisk träff 2024-09-05

Structure Activity of β-Amidomethyl Vinyl Sulfones as Covalent Inhibitors of <i>Chikungunya</i> nsP2 Cysteine Protease with Antialphavirus Activity.

Ghoshal A, Asressu KH, Hossain MA, Brown PJ, Nandakumar M, Vala A, Merten EM, Sears JD, Law I, Burdick JE, Morales NL, Perveen S, Pearce KH, Popov KI, Moorman NJ, Heise MT, Willson TM.

J Med Chem · research-article; journal article · DOI 10.1021/acs.jmedchem.4c01346

Bibliografisk träff 2023-08-15

Modification of N-hydroxycytidine yields a novel lead compound exhibiting activity against the Venezuelan equine encephalitis virus.

Downs IL, David Ordonez Luna A, Kota KP, Rubin SK, Shirsekar SS, Ward MD, Panchal RG, Litosh VA.

Bioorg Med Chem Lett · research support, non-u.s. gov't; journal article · DOI 10.1016/j.bmcl.2023.129432

Bibliografisk träff 2023-02-08

Synthesis and biological evaluation of new β-D-N<sup>4</sup>-hydroxycytidine analogs against SARS-CoV-2, influenza viruses and DENV-2.

An YJ, Choi SM, Choi ER, Nam YE, Seo EW, Ahn SB, Jang Y, Kim M, Cho JH.

Bioorg Med Chem Lett · brief-report; research support, non-u.s. gov't; journal article · DOI 10.1016/j.bmcl.2023.129174

Bibliografisk träff 2022-10-13

Discovery of Chlorofluoroacetamide-Based Covalent Inhibitors for Severe Acute Respiratory Syndrome Coronavirus 2 3CL Protease.

Hirose Y, Shindo N, Mori M, Onitsuka S, Isogai H, Hamada R, Hiramoto T, Ochi J, Takahashi D, Ueda T, Caaveiro JMM, Yoshida Y, Ohdo S, Matsunaga N, Toba S, Sasaki M, Orba Y, Sawa H, Sato A, Kawanishi E, Ojida A.

J Med Chem · research support, non-u.s. gov't; journal article · DOI 10.1021/acs.jmedchem.2c01081

Bibliografisk träff 2021-04-15

Phenoxazine nucleoside derivatives with a multiple activity against RNA and DNA viruses.

Kozlovskaya LI, Volok VP, Shtro AA, Nikolaeva YV, Chistov AA, Matyugina ES, Belyaev ES, Jegorov AV, Snoeck R, Korshun VA, Andrei G, Osolodkin DI, Ishmukhametov AA, Aralov AV.

Eur J Med Chem · research-article; journal article · DOI 10.1016/j.ejmech.2021.113467

Bibliografisk träff 2020-11-13

Targeting SARS-CoV-2 Proteases and Polymerase for COVID-19 Treatment: State of the Art and Future Opportunities.

Cannalire R, Cerchia C, Beccari AR, Di Leva FS, Summa V.

J Med Chem · review-article; review; journal article · DOI 10.1021/acs.jmedchem.0c01140

Bibliografisk träff 2019-12-16

Drug Metabolism by the Mitochondrial Amidoxime Reducing Component (mARC): Rapid Assay and Identification of New Substrates.

Indorf P, Kubitza C, Scheidig AJ, Kunze T, Clement B.

J Med Chem · journal article · DOI 10.1021/acs.jmedchem.9b01483

Bibliografisk träff 2012-10-18

Novel cytidine-based orotidine-5'-monophosphate decarboxylase inhibitors with an unusual twist.

Purohit MK, Poduch E, Wei LW, Crandall IE, To T, Kain KC, Pai EF, Kotra LP.

J Med Chem · research support, non-u.s. gov't; journal article · DOI 10.1021/jm301176r