ActiQs / Forskning

PUBLIKATIONSREGISTRET

Gå till forskningen.

Publikationsdata från Europe PMC och PubMed. Följ källhänvisningar från ämnesregistret till originalpublikationerna.

Publikationer som ChEBI hänvisar till för bemcentinib. Visa hela publikationsregistret

En publikationsträff är inte en slutsats. Publikationslistan visar bibliografiska uppgifter. Eventuella forskningsutdrag visas separat med originalunderlag. En källhänvisning visar inte i sig effekt, dosering eller säkerhet.

Publikationer i urvalet

13 träffar

Bibliografisk träff 2024-06-24

Discovery of Dual MER/AXL Kinase Inhibitors as Bifunctional Small Molecules for Inhibiting Tumor Growth and Enhancing Tumor Immune Microenvironment.

Li MC, Lai YL, Kuo PH, Reddy JS, Chen CM, Manimala J, Wang PC, Wu MS, Chang CY, Yang CM, Lin CY, Huang YC, Chiu CH, Chang L, Lin WH, Yeh TK, Yen WC, Hsieh HP.

J Med Chem · research support, non-u.s. gov't; research-article; journal article · DOI 10.1021/acs.jmedchem.4c00400

Bibliografisk träff 2024-05-03

Recent discovery and development of AXL inhibitors as antitumor agents.

Liu Z, Chen L, Zhang J, Yang J, Xiao X, Shan L, Mao W.

Eur J Med Chem · review; journal article · DOI 10.1016/j.ejmech.2024.116475

Bibliografisk träff 2023-12-30

Structure-activity relationship study of 1,6-naphthyridinone derivatives as selective type II AXL inhibitors with potent antitumor efficacy.

Zhuo L, Guo M, Zhang S, Wu J, Wang M, Shen Y, Peng X, Wang Z, Jiang W, Huang W.

Eur J Med Chem · journal article · DOI 10.1016/j.ejmech.2023.116090

Bibliografisk träff 2023-12-14

Discovery of a 1,6-naphthyridin-4-one-based AXL inhibitor with improved pharmacokinetics and enhanced in vivo antitumor efficacy.

Lan Y, Peng X, Ji Y, Su Y, Duan W, Ai J, Zhang H.

Eur J Med Chem · journal article · DOI 10.1016/j.ejmech.2023.116045

Bibliografisk träff 2022-11-10

Discovery of 3-Aminopyrazole Derivatives as New Potent and Orally Bioavailable AXL Inhibitors.

Chan S, Zhang Y, Wang J, Yu Q, Peng X, Zou J, Zhou L, Tan L, Duan Y, Zhou Y, Hur H, Ai J, Wang Z, Ren X, Zhang Z, Ding K.

J Med Chem · research support, non-u.s. gov't; journal article · DOI 10.1021/acs.jmedchem.2c01346

Bibliografisk träff 2022-07-20

Structure-based discovery of potent inhibitors of Axl: design, synthesis, and biological evaluation.

Wu S, Liao M, Li M, Sun M, Xi N, Zeng Y.

RSC Med Chem · research-article; journal article · DOI 10.1039/d2md00153e

Bibliografisk träff 2022-03-06

Structure-based discovery of receptor tyrosine kinase AXL degraders with excellent anti-tumor activity by selectively degrading AXL and inducing methuosis.

Shi W, Feng Z, Chi F, Zhou J, Qiu Q, Jiang Y, Chen S, Zhong Y, Jia H, Huang W, Qian H.

Eur J Med Chem · journal article · DOI 10.1016/j.ejmech.2022.114253

Bibliografisk träff 2021-04-25

Discovery of pyrrolo[2,3-d]pyrimidine derivatives as potent Axl inhibitors: Design, synthesis and biological evaluation.

Xu D, Sun D, Wang W, Peng X, Zhan Z, Ji Y, Shen Y, Geng M, Ai J, Duan W.

Eur J Med Chem · journal article · DOI 10.1016/j.ejmech.2021.113497

Bibliografisk träff 2021-03-18

Discovery of a Pyrimidinedione Derivative as a Potent and Orally Bioavailable Axl Inhibitor.

Zhang H, Peng X, Dai Y, Shao J, Ji Y, Sun Y, Liu B, Cheng X, Ai J, Duan W.

J Med Chem · research support, non-u.s. gov't; journal article · DOI 10.1021/acs.jmedchem.0c02093

Bibliografisk träff 2021-02-04

Recent Developments in the Use of Kinase Inhibitors for Management of Viral Infections.

Raghuvanshi R, Bharate SB.

J Med Chem · research support, non-u.s. gov't; journal article · DOI 10.1021/acs.jmedchem.0c01467

Bibliografisk träff 2018-02-21

Development of Potent Inhibitors of Receptor Tyrosine Kinases by Ligand-Based Drug Design and Target-Biased Phenotypic Screening.

Myers SH, Temps C, Houston DR, Brunton VG, Unciti-Broceta A.

J Med Chem · research support, non-u.s. gov't; rapid-communication; journal article · DOI 10.1021/acs.jmedchem.7b01605

Bibliografisk träff 2016-07-19

4-Oxo-1,4-dihydroquinoline-3-carboxamide Derivatives as New Axl Kinase Inhibitors.

Tan L, Zhang Z, Gao D, Luo J, Tu ZC, Li Z, Peng L, Ren X, Ding K.

J Med Chem · research support, non-u.s. gov't; journal article · DOI 10.1021/acs.jmedchem.6b00608

Bibliografisk träff 2015-11-20

AXL Inhibitors in Cancer: A Medicinal Chemistry Perspective.

Myers SH, Brunton VG, Unciti-Broceta A.

J Med Chem · research support, non-u.s. gov't; review; journal article · DOI 10.1021/acs.jmedchem.5b01273