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Publikationer i urvalet

12 träffar

Bibliografisk träff 2023-03-13

Discovery of BGB-8035, a Highly Selective Covalent Inhibitor of Bruton's Tyrosine Kinase for B-Cell Malignancies and Autoimmune Diseases.

Guo Y, Hu N, Liu Y, Zhang W, Yu D, Shi G, Zhang B, Yin L, Wei M, Yuan X, Luo L, Wang F, Song X, Xin L, Wei Q, Li Y, Guo Y, Chen S, Zhang T, Zhang S, Zhou X, Zhang C, Su D, Liu J, Cheng Z, Zhang J, Xing H, Sun H, Li X, Zhao Y, He M, Wu Y, Guo Y, Sun X, Tian A, Zhou C, Young S, Liu X, Wang L, Wang Z.

J Med Chem · journal article · DOI 10.1021/acs.jmedchem.2c01938

Bibliografisk träff 2022-10-11

Advanced approaches of developing targeted covalent drugs.

Gai C, Harnor SJ, Zhang S, Cano C, Zhuang C, Zhao Q.

RSC Med Chem · review-article; review; journal article · DOI 10.1039/d2md00216g

Bibliografisk träff 2022-08-26

Pyrazole-containing pharmaceuticals: target, pharmacological activity, and their SAR studies.

Li G, Cheng Y, Han C, Song C, Huang N, Du Y.

RSC Med Chem · review-article; review; journal article · DOI 10.1039/d2md00206j

Bibliografisk träff 2022-07-15

Design, synthesis, and biological evaluation of pyrrolopyrimidine derivatives as novel Bruton's tyrosine kinase (BTK) inhibitors.

Yang M, Jiang H, Yang Z, Liu X, Sun H, Hao M, Hu J, Chen X, Jin J, Wang X.

Eur J Med Chem · journal article · DOI 10.1016/j.ejmech.2022.114611

Bibliografisk träff 2022-04-19

The Ascension of Targeted Covalent Inhibitors.

Singh J.

J Med Chem · review; journal article · DOI 10.1021/acs.jmedchem.1c02134

Bibliografisk träff 2022-01-31

Discovery of Pteridine-7(8<i>H</i>)-one Derivatives as Potent and Selective Inhibitors of Bruton's Tyrosine Kinase (BTK).

Dou D, Diao Y, Sha W, Su R, Tong L, Li W, Leng L, Xie L, Yu Z, Song H, Shen Z, Zhu L, Zhao Z, Xie H, Chen Z, Li H, Xu Y.

J Med Chem · research support, non-u.s. gov't; journal article · DOI 10.1021/acs.jmedchem.1c02208

Bibliografisk träff 2022-01-15

Optimization of a novel piperazinone series as potent selective peripheral covalent BTK inhibitors.

Ma B, Metrick CM, Gu C, Hoemberger M, Bajrami B, Bame E, Huang J, Mingueneau M, Murugan P, Santoro JC, Tang H, Wang T, Hopkins BT.

Bioorg Med Chem Lett · journal article · DOI 10.1016/j.bmcl.2022.128549

Bibliografisk träff 2021-10-21

Discovery of 1-Amino-1<i>H</i>-imidazole-5-carboxamide Derivatives as Highly Selective, Covalent Bruton's Tyrosine Kinase (BTK) Inhibitors.

Ma C, Li Q, Zhao M, Fan G, Zhao J, Zhang D, Yang S, Zhang S, Gao D, Mao L, Zhu L, Li W, Xu G, Jiang Y, Ding Q.

J Med Chem · research support, non-u.s. gov't; journal article · DOI 10.1021/acs.jmedchem.1c01559

Bibliografisk träff 2021-07-29

Structure-activity relationship investigation for imidazopyrazole-3-carboxamide derivatives as novel selective inhibitors of Bruton's tyrosine kinase.

Zhang D, Xu G, Zhao J, Wang Y, Wu X, He X, Li W, Zhang S, Yang S, Ma C, Jiang Y, Ding Q.

Eur J Med Chem · journal article · DOI 10.1016/j.ejmech.2021.113724

Bibliografisk träff 2021-02-04

Recent Developments in the Use of Kinase Inhibitors for Management of Viral Infections.

Raghuvanshi R, Bharate SB.

J Med Chem · research support, non-u.s. gov't; journal article · DOI 10.1021/acs.jmedchem.0c01467

Bibliografisk träff 2020-06-30

Progress toward a Glycoprotein VI Modulator for the Treatment of Thrombosis.

Foster H, Wilson C, Philippou H, Foster R.

J Med Chem · research support, non-u.s. gov't; journal article · DOI 10.1021/acs.jmedchem.0c00262

Bibliografisk träff 2019-08-19

Discovery of Zanubrutinib (BGB-3111), a Novel, Potent, and Selective Covalent Inhibitor of Bruton's Tyrosine Kinase.

Guo Y, Liu Y, Hu N, Yu D, Zhou C, Shi G, Zhang B, Wei M, Liu J, Luo L, Tang Z, Song H, Guo Y, Liu X, Su D, Zhang S, Song X, Zhou X, Hong Y, Chen S, Cheng Z, Young S, Wei Q, Wang H, Wang Q, Lv L, Wang F, Xu H, Sun H, Xing H, Li N, Zhang W, Wang Z, Liu G, Sun Z, Zhou D, Li W, Liu L, Wang L, Wang Z.

J Med Chem · research support, non-u.s. gov't; journal article · DOI 10.1021/acs.jmedchem.9b00687