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Publikationer i urvalet

4 träffar

Bibliografisk träff 2022-04-28

Development of Azaindole-Based Frameworks as Potential Antiviral Agents and Their Future Perspectives.

Urvashi, Senthil Kumar JB, Das P, Tandon V.

J Med Chem · research support, non-u.s. gov't; review; journal article · DOI 10.1021/acs.jmedchem.2c00444

Bibliografisk träff 2021-04-18

Substituted N-(4-amino-2-chlorophenyl)-5-chloro-2-hydroxybenzamide analogues potently inhibit respiratory syncytial virus (RSV) replication and RSV infection-associated inflammatory responses.

Xu J, Wu W, Chen H, Xue Y, Bao X, Zhou J.

Bioorg Med Chem · research support, non-u.s. gov't; research-article; journal article; research support, n.i.h., extramural · DOI 10.1016/j.bmc.2021.116157

Bibliografisk träff 2020-06-15

Discovery of 3-({5-Chloro-1-[3-(methylsulfonyl)propyl]-1H-indol-2-yl}methyl)-1-(2,2,2-trifluoroethyl)-1,3-dihydro-2H-imidazo[4,5-c]pyridin-2-one (JNJ-53718678), a Potent and Orally Bioavailable Fusion Inhibitor of Respiratory Syncytial Virus.

Vendeville S, Tahri A, Hu L, Demin S, Cooymans L, Vos A, Kwanten L, Van den Berg J, Battles MB, McLellan JS, Koul A, Raboisson P, Roymans D, Jonckers THM.

J Med Chem · research support, u.s. gov't, non-p.h.s.; journal article · DOI 10.1021/acs.jmedchem.0c00226

Bibliografisk träff 2018-11-21

State of the Art in Respiratory Syncytial Virus Drug Discovery and Development.

Cockerill GS, Good JAD, Mathews N.

J Med Chem · journal article · DOI 10.1021/acs.jmedchem.8b01361

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Publikationer i urvalet

Development of Azaindole-Based Frameworks as Potential Antiviral Agents and Their Future Perspectives.

Substituted N-(4-amino-2-chlorophenyl)-5-chloro-2-hydroxybenzamide analogues potently inhibit respiratory syncytial virus (RSV) replication and RSV infection-associated inflammatory responses.

Discovery of 3-({5-Chloro-1-[3-(methylsulfonyl)propyl]-1<i>H</i>-indol-2-yl}methyl)-1-(2,2,2-trifluoroethyl)-1,3-dihydro-2<i>H</i>-imidazo[4,5-<i>c</i>]pyridin-2-one (JNJ-53718678), a Potent and Orally Bioavailable Fusion Inhibitor of Respiratory Syncytial Virus.

State of the Art in Respiratory Syncytial Virus Drug Discovery and Development.