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Publikationer i urvalet

6 träffar

Bibliografisk träff 2019-02-06

Viral and metazoan poxins are cGAMP-specific nucleases that restrict cGAS-STING signalling.

Eaglesham JB, Pan Y, Kupper TS, Kranzusch PJ.

Nature · research support, non-u.s. gov't; research-article; journal article; research support, n.i.h., extramural · DOI 10.1038/s41586-019-0928-6

Bibliografisk träff 2017-10-25

The catalytic mechanism of cyclic GMP-AMP synthase (cGAS) and implications for innate immunity and inhibition.

Hall J, Ralph EC, Shanker S, Wang H, Byrnes LJ, Horst R, Wong J, Brault A, Dumlao D, Smith JF, Dakin LA, Schmitt DC, Trujillo J, Vincent F, Griffor M, Aulabaugh AE.

Protein Sci · research-article; journal article · DOI 10.1002/pro.3304

Bibliografisk träff 2017-04-07

Cyclic GMP-AMP as an Endogenous Second Messenger in Innate Immune Signaling by Cytosolic DNA.

Kato K, Omura H, Ishitani R, Nureki O.

Annu Rev Biochem · review; journal article · DOI 10.1146/annurev-biochem-061516-044813

Bibliografisk träff 2013-08-01

Structure-function analysis of STING activation by c[G(2',5')pA(3',5')p] and targeting by antiviral DMXAA.

Gao P, Ascano M, Zillinger T, Wang W, Dai P, Serganov AA, Gaffney BL, Shuman S, Jones RA, Deng L, Hartmann G, Barchet W, Tuschl T, Patel DJ.

Cell · research support, non-u.s. gov't; research-article; journal article; research support, n.i.h., extramural · DOI 10.1016/j.cell.2013.07.023

Bibliografisk träff 2013-06-06

Cyclic GMP-AMP containing mixed phosphodiester linkages is an endogenous high-affinity ligand for STING.

Zhang X, Shi H, Wu J, Zhang X, Sun L, Chen C, Chen ZJ.

Mol Cell · research-article; journal article; research support, n.i.h., extramural · DOI 10.1016/j.molcel.2013.05.022

Bibliografisk träff 2013-05-30

cGAS produces a 2'-5'-linked cyclic dinucleotide second messenger that activates STING.

Ablasser A, Goldeck M, Cavlar T, Deimling T, Witte G, Röhl I, Hopfner KP, Ludwig J, Hornung V.

Nature · research support, non-u.s. gov't; research-article; journal article; research support, n.i.h., extramural · DOI 10.1038/nature12306