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Publikationer i urvalet

13 träffar

Bibliografisk träff 2023-12-09

AcGlcAs: A Novel P53-Targeting Arsenical with Potent Cellular Uptake and Cancer Cell Selectivity.

Liang Y, An Q, Song H, Tang Y, Xiao S, Wu J, Yan N, Yu B, Cao X, Lu M.

J Med Chem · research support, non-u.s. gov't; journal article · DOI 10.1021/acs.jmedchem.3c00104

Bibliografisk träff 2022-04-29

Design, synthesis and antitumor evaluation of novel 1H-indole-2-carboxylic acid derivatives targeting 14-3-3η protein.

Gao Z, Fan T, Chen L, Yang M, Wai Wong VK, Chen D, Liu Z, Zhou Y, Wu W, Qiu Z, Zhang C, Li Y, Jiang Y.

Eur J Med Chem · journal article · DOI 10.1016/j.ejmech.2022.114402

Bibliografisk träff 2021-02-08

Medulloblastoma drugs in development: Current leads, trials and drawbacks.

Wen J, Hadden MK.

Eur J Med Chem · research-article; review; journal article · DOI 10.1016/j.ejmech.2021.113268

Bibliografisk träff 2020-12-04

Xanthenes in Medicinal Chemistry - Synthetic strategies and biological activities.

Maia M, Resende DISP, Durães F, Pinto MMM, Sousa E.

Eur J Med Chem · review; journal article · DOI 10.1016/j.ejmech.2020.113085

Bibliografisk träff 2018-02-01

Optimization of antimalarial, and anticancer activities of (E)-methyl 2-(7-chloroquinolin-4-ylthio)-3-(4-hydroxyphenyl) acrylate.

Romero JA, Acosta ME, Gamboa ND, Mijares MR, De Sanctis JB, Charris JE.

Bioorg Med Chem · research support, non-u.s. gov't; journal article · DOI 10.1016/j.bmc.2017.12.022

Bibliografisk träff 2016-03-03

DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.

Chen M, Suzuki A, Thakkar S, Yu K, Hu C, Tong W.

Drug Discov Today · review; journal article · DOI 10.1016/j.drudis.2016.02.015

Bibliografisk träff 2015-05-15

Synthesis and antiproliferative activity of α-branched α,β-unsaturated ketones in human hematological and solid cancer cell lines.

Karpavičienė I, Valiulienė G, Raškevičius V, Lebedytė I, Brukštus A, Kairys V, Navakauskienė R, Čikotienė I.

Eur J Med Chem · research support, non-u.s. gov't; journal article · DOI 10.1016/j.ejmech.2015.05.012

Bibliografisk träff 2014-06-11

Dithiaarsanes induce oxidative stress-mediated apoptosis in HL-60 cells by selectively targeting thioredoxin reductase.

Liu Y, Duan D, Yao J, Zhang B, Peng S, Ma H, Song Y, Fang J.

J Med Chem · research support, non-u.s. gov't; journal article · DOI 10.1021/jm500221p

Bibliografisk träff 2011-12-15

Translating clinical findings into knowledge in drug safety evaluation--drug induced liver injury prediction system (DILIps).

Liu Z, Shi Q, Ding D, Kelly R, Fang H, Tong W.

PLoS Comput Biol · research support, u.s. gov't, p.h.s.; research-article; journal article · DOI 10.1371/journal.pcbi.1002310

Bibliografisk träff 2010-09-15

A predictive ligand-based Bayesian model for human drug-induced liver injury.

Ekins S, Williams AJ, Xu JJ.

Drug Metab Dispos · journal article · DOI 10.1124/dmd.110.035113

Bibliografisk träff 2010-07-01

Developing structure-activity relationships for the prediction of hepatotoxicity.

Greene N, Fisk L, Naven RT, Note RR, Patel ML, Pelletier DJ.

Chem Res Toxicol · journal article · DOI 10.1021/tx1000865

Bibliografisk träff 2007-07-18

Targeting thioredoxin reductase is a basis for cancer therapy by arsenic trioxide.

Lu J, Chew EH, Holmgren A.

Proc Natl Acad Sci U S A · research support, non-u.s. gov't; research-article; journal article · DOI 10.1073/pnas.0701549104

Bibliografisk träff 2007-04-30

SAR of the arylpiperazine moiety of obeline somatostatin sst1 receptor antagonists.

Hurth K, Enz A, Floersheim P, Gentsch C, Hoyer D, Langenegger D, Neumann P, Pfäffli P, Sorg D, Swoboda R, Vassout A, Troxler T.

Bioorg Med Chem Lett · journal article · DOI 10.1016/j.bmcl.2007.04.078