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Publikationer i urvalet

12 träffar

Bibliografisk träff 2023-07-19

A preclinical secondary pharmacology resource illuminates target-adverse drug reaction associations of marketed drugs.

Sutherland JJ, Yonchev D, Fekete A, Urban L.

Nat Commun · research support, non-u.s. gov't; research-article; journal article · DOI 10.1038/s41467-023-40064-9

Bibliografisk träff 2016-07-19

Targeting the Translesion Synthesis Pathway for the Development of Anti-Cancer Chemotherapeutics.

Korzhnev DM, Hadden MK.

J Med Chem · review; journal article · DOI 10.1021/acs.jmedchem.6b00596

Bibliografisk träff 2015-12-14

Perspectives on the Two-Pore Domain Potassium Channel TREK-1 (TWIK-Related K(+) Channel 1). A Novel Therapeutic Target?

Vivier D, Bennis K, Lesage F, Ducki S.

J Med Chem · research support, non-u.s. gov't; review; journal article · DOI 10.1021/acs.jmedchem.5b00671

Bibliografisk träff 2012-05-15

Classification of inhibitors of hepatic organic anion transporting polypeptides (OATPs): influence of protein expression on drug-drug interactions.

Karlgren M, Vildhede A, Norinder U, Wisniewski JR, Kimoto E, Lai Y, Haglund U, Artursson P.

J Med Chem · research support, non-u.s. gov't; research-article; journal article · DOI 10.1021/jm300212s

Bibliografisk träff 2011-02-26

Molecular properties affecting fast dissociation from the D2 receptor.

Tresadern G, Bartolome JM, Macdonald GJ, Langlois X.

Bioorg Med Chem · journal article · DOI 10.1016/j.bmc.2011.02.033

Bibliografisk träff 2010-09-15

A predictive ligand-based Bayesian model for human drug-induced liver injury.

Ekins S, Williams AJ, Xu JJ.

Drug Metab Dispos · journal article · DOI 10.1124/dmd.110.035113

Bibliografisk träff 2008-09-13

Structural requirements for drug inhibition of the liver specific human organic cation transport protein 1.

Ahlin G, Karlsson J, Pedersen JM, Gustavsson L, Larsson R, Matsson P, Norinder U, Bergström CA, Artursson P.

J Med Chem · research support, non-u.s. gov't; journal article · DOI 10.1021/jm8003152

Bibliografisk träff 2008-05-06

Prediction and identification of drug interactions with the human ATP-binding cassette transporter multidrug-resistance associated protein 2 (MRP2; ABCC2).

Pedersen JM, Matsson P, Bergström CA, Norinder U, Hoogstraate J, Artursson P.

J Med Chem · research support, non-u.s. gov't; journal article · DOI 10.1021/jm7015683

Bibliografisk träff 2004-08-01

[Drug-induced liver injury; fourteenth updated edition of the bibliographic database of liver injuries and related drugs].

Biour M, Ben Salem C, Chazouillères O, Grangé JD, Serfaty L, Poupon R.

Gastroenterol Clin Biol · bibliography; journal article · DOI 10.1016/s0399-8320(04)95062-2

Bibliografisk träff 1999-08-01

Synthesis, evaluation, and comparative molecular field analysis of 1-phenyl-3-amino-1,2,3,4-tetrahydronaphthalenes as ligands for histamine H(1) receptors.

Bucholtz EC, Brown RL, Tropsha A, Booth RG, Wyrick SD.

J Med Chem · research support, u.s. gov't, p.h.s.; research support, non-u.s. gov't; journal article · DOI 10.1021/jm980428x

Bibliografisk träff 1998-05-01

Molecular modeling of phenothiazines and related drugs as multidrug resistance modifiers: a comparative molecular field analysis study.

Pajeva I, Wiese M.

J Med Chem · comparative study; research support, non-u.s. gov't; journal article · DOI 10.1021/jm970786k

Bibliografisk träff 1984-12-01

Functional group contributions to drug-receptor interactions.

Andrews PR, Craik DJ, Martin JL.

J Med Chem · comparative study; journal article · DOI 10.1021/jm00378a021