Chemical profile of persian lime seeds (Citrus Limettioides T.): Focus on limonoids and polyphenols.
Silva TRD, Silva AJRD.
An Acad Bras Cienc · journal article · DOI 10.1590/0001-3765202320230322 PUBLIKATIONSREGISTRET
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27 träffarPharmacokinetic and pharmacodynamic drug-drug interaction of Nomilin with atorvastatin in hyperlipidemic mice.
Ding Y, Guan H, Yan Y, Chen Y, Huang C.
Heliyon · research-article; journal article · DOI 10.1016/j.heliyon.2023.e22016Nomilin and its analogue obacunone alleviate NASH and hepatic fibrosis in mice via enhancing antioxidant and anti-inflammation capacity.
Han Y, Luo L, Li H, Zhang L, Yan Y, Fang M, Yu J, Gao X, Liu Y, Huang C, Fan S.
Biofactors · journal article · DOI 10.1002/biof.1987Pregnane X receptor agonist nomilin extends lifespan and healthspan in preclinical models through detoxification functions.
Fan S, Yan Y, Xia Y, Zhou Z, Luo L, Zhu M, Han Y, Yao D, Zhang L, Fang M, Peng L, Yu J, Liu Y, Gao X, Guan H, Li H, Wang C, Wu X, Zhu H, Cao Y, Huang C.
Nat Commun · research support, non-u.s. gov't; research-article; journal article · DOI 10.1038/s41467-023-39118-9Nomilin Attenuates Lipopolysaccharide-Induced Inflammatory Response by Binding with Myeloid Differentiation Protein-2.
Chen Y, Guo S, Chen G, Liu C, Zhang M, Wang X.
Comb Chem High Throughput Screen · research support, non-u.s. gov't; journal article · DOI 10.2174/1386207326666230418112827Nomilin and Its Analogues in Citrus Fruits: A Review of Its Health Promotion Effects and Potential Application in Medicine.
Zhou Z, Yan Y, Li H, Feng Y, Huang C, Fan S.
Molecules · review-article; review; journal article · DOI 10.3390/molecules28010269Nomilin from Yuzu Seed Has In Vitro Antioxidant Activity and Downregulates Melanogenesis in B16F10 Melanoma Cells through the PKA/CREB Signaling Pathway.
Choi MH, Yang SH, Kim ND, Shin HJ.
Antioxidants (Basel) · research-article; journal article · DOI 10.3390/antiox11091636Molecular docking study of GSK-3β interaction with nomilin, kihadanin B, and related limonoids and triterpenes with a furyl-δ-lactone core.
Vergoten G, Bailly C.
J Biochem Mol Toxicol · journal article · DOI 10.1002/jbt.23130Limonoids isolated from the Fortunella crassifolia and the Citrus junos with their cell death-inducing activity on Adriamycin-treated cancer cell.
Kitagawa T, Matsumoto T, Imahori D, Kobayashi M, Okayama M, Ohta T, Yoshida T, Watanabe T.
J Nat Med · journal article · DOI 10.1007/s11418-021-01528-8Cytochrome P450 3A4-Mediated Bioactivation and Its Role in Nomilin-Induced Hepatotoxicity.
Zhang L, Liu Q, Pan Y, Qi X, Li Y, Chen C, Sun J.
Chem Res Toxicol · journal article · DOI 10.1021/acs.chemrestox.0c00228Nomilin targets the Keap1-Nrf2 signalling and ameliorates the development of osteoarthritis.
Xue XH, Xue JX, Hu W, Shi FL, Yang Y.
J Cell Mol Med · research support, non-u.s. gov't; research-article; journal article · DOI 10.1111/jcmm.15484Nomilin protects against cerebral ischemia-reperfusion induced neurological deficits and blood-brain barrier disruption via the Nrf2 pathway.
Shi YS, Zhang Y, Liu B, Li CB, Wu J, Li Y.
Food Funct · journal article · DOI 10.1039/c9fo01481kVariation in limonin and nomilin content in citrus fruits of eight varieties determined by modified HPLC.
Huang S, Liu X, Xiong B, Qiu X, Sun G, Wang X, Zhang X, Dong Z, Wang Z.
Food Sci Biotechnol · research-article; journal article · DOI 10.1007/s10068-018-0509-8Identification of key amino acid residues in the hTGR5-nomilin interaction and construction of its binding model.
Sasaki T, Mita M, Ikari N, Kuboyama A, Hashimoto S, Kaneko T, Ishiguro M, Shimizu M, Inoue J, Sato R.
PLoS One · research-article; journal article · DOI 10.1371/journal.pone.0179226Citrus nomilin down-regulates TNF-α-induced proliferation of aortic smooth muscle cells via apoptosis and inhibition of IκB.
Kim J, Chakraborty S, Jayaprakasha GK, Muthuchamy M, Patil BS.
Eur J Pharmacol · journal article · DOI 10.1016/j.ejphar.2017.05.043Temporal and spatial variations on accumulation of nomilin and limonin in the pummelos.
Wang F, Yu X, Liu X, Shen W, Zhu S, Zhao X.
Plant Physiol Biochem · journal article · DOI 10.1016/j.plaphy.2016.04.039A Rapid, Selective and Sensitive UPLC-MS/MS Method for Quantification of Nomilin in Rat Plasma and Its Application in a Pharmacokinetic Study.
Cai Y, Zhang S, Wang Q, Sun H, Zhou M, Hu S, Xiang Z.
Planta Med · research support, non-u.s. gov't; validation study; journal article · DOI 10.1055/s-0035-1558157Citrus limonoid nomilin inhibits osteoclastogenesis in vitro by suppression of NFATc1 and MAPK signaling pathways.
Kimira Y, Taniuchi Y, Nakatani S, Sekiguchi Y, Kim HJ, Shimizu J, Ebata M, Wada M, Matsumoto A, Mano H.
Phytomedicine · research support, non-u.s. gov't; journal article · DOI 10.1016/j.phymed.2015.08.013Simultaneous purification of limonin, nomilin and isoobacunoic acid from pomelo fruit (Citrus grandis) segment membrane.
Xiang Y, Cao J, Luo F, Wang D, Chen W, Li X, Sun C, Chen K.
J Food Sci · research support, non-u.s. gov't; journal article · DOI 10.1111/1750-3841.12581Nomilin as an anti-obesity and anti-hyperglycemic agent.
Sato R.
Vitam Horm · research support, non-u.s. gov't; review; journal article · DOI 10.1016/b978-0-12-407766-9.00018-3Nomilin inhibits tumor-specific angiogenesis by downregulating VEGF, NO and proinflammatory cytokine profile and also by inhibiting the activation of MMP-2 and MMP-9.
Pratheeshkumar P, Kuttan G.
Eur J Pharmacol · journal article · DOI 10.1016/j.ejphar.2011.07.029Anti-obesity and anti-hyperglycemic effects of the dietary citrus limonoid nomilin in mice fed a high-fat diet.
Ono E, Inoue J, Hashidume T, Shimizu M, Sato R.
Biochem Biophys Res Commun · research support, non-u.s. gov't; journal article · DOI 10.1016/j.bbrc.2011.06.055Nomilin inhibits metastasis via induction of apoptosis and regulates the activation of transcription factors and the cytokine profile in B16F-10 cells.
Pratheeshkumar P, Raphael TJ, Kuttan G.
Integr Cancer Ther · journal article · DOI 10.1177/1534735411403307Evaluation of the antioxidant capacity of limonin, nomilin, and limonin glucoside.
Breksa AP, Manners GD.
J Agric Food Chem · journal article · DOI 10.1021/jf060901cEffect of limonin and nomilin on HIV-1 replication on infected human mononuclear cells.
Battinelli L, Mengoni F, Lichtner M, Mazzanti G, Saija A, Mastroianni CM, Vullo V.
Planta Med · journal article · DOI 10.1055/s-2003-45099Calorimetric evidence of differentiated transport of limonin and nomilin through biomembranes.
Castelli F, Giuffrida N, Tringali C, Ruberto G.
J Agric Food Chem · research support, non-u.s. gov't; journal article · DOI 10.1021/jf991282tInhibition of benzo[a]pyrene-induced forestomach neoplasia in mice by citrus limonoids.
Lam LK, Hasegawa S.
Nutr Cancer · journal article · DOI 10.1080/01635588909513999