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Publikationer i urvalet

13 träffar

Bibliografisk träff 2014-01-27

Structural basis of microtubule stabilization by laulimalide and peloruside A.

Prota AE, Bargsten K, Northcote PT, Marsh M, Altmann KH, Miller JH, Díaz JF, Steinmetz MO.

Angew Chem Int Ed Engl · research support, non-u.s. gov't; journal article · DOI 10.1002/anie.201307749

Bibliografisk träff 2014-01-01

Resistance to peloruside A and laulimalide: functional significance of acquired βI-tubulin mutations at sites important for drug-tubulin binding.

Kanakkanthara A, Eras J, Northcote PT, Cabral F, Miller JH.

Curr Cancer Drug Targets · research support, non-u.s. gov't; journal article · DOI 10.2174/1568009613666131113101151

Bibliografisk träff 2013-11-01

Laulimalide and peloruside A inhibit mitosis of Saccharomyces cerevisiae by preventing microtubule depolymerisation-dependent steps in chromosome separation and nuclear positioning.

Best HA, Matthews JH, Heathcott RW, Hanna R, Leahy DC, Coorey NV, Bellows DS, Atkinson PH, Miller JH.

Mol Biosyst · research support, non-u.s. gov't; journal article · DOI 10.1039/c3mb70211a

Bibliografisk träff 2013-10-24

Docking and molecular dynamics studies of the binding between Peloruside A and tubulin.

Liao SY, Mo GQ, Chen JC, Zheng KC.

J Enzyme Inhib Med Chem · research support, non-u.s. gov't; journal article · DOI 10.3109/14756366.2013.845816

Bibliografisk träff 2013-09-24

Microtubule-stabilizing agents delay the onset of EAE through inhibition of migration.

O'Sullivan D, Miller JH, Northcote PT, La Flamme AC.

Immunol Cell Biol · research support, non-u.s. gov't; journal article · DOI 10.1038/icb.2013.47

Bibliografisk träff 2012-05-17

Microtubule stabilization by peloruside A and paclitaxel rescues degenerating neurons from okadaic acid-induced tau phosphorylation.

Das V, Miller JH.

Eur J Neurosci · research support, non-u.s. gov't; journal article · DOI 10.1111/j.1460-9568.2012.08084.x

Bibliografisk träff 2012-05-15

Acquired resistance to peloruside A and laulimalide is associated with downregulation of vimentin in human ovarian carcinoma cells.

Kanakkanthara A, Rawson P, Northcote PT, Miller JH.

Pharm Res · research support, non-u.s. gov't; journal article · DOI 10.1007/s11095-012-0773-x

Bibliografisk träff 2012-02-04

Chemical genetic profiling of the microtubule-targeting agent peloruside A in budding yeast Saccharomyces cerevisiae.

Wilmes A, Hanna R, Heathcott RW, Northcote PT, Atkinson PH, Bellows DS, Miller JH.

Gene · research support, non-u.s. gov't; journal article · DOI 10.1016/j.gene.2012.01.072

Bibliografisk träff 2011-12-16

βII-tubulin and βIII-tubulin mediate sensitivity to peloruside A and laulimalide, but not paclitaxel or vinblastine, in human ovarian carcinoma cells.

Kanakkanthara A, Northcote PT, Miller JH.

Mol Cancer Ther · research support, non-u.s. gov't; journal article · DOI 10.1158/1535-7163.mct-11-0614

Bibliografisk träff 2011-10-01

Mutations in the β-tubulin binding site for peloruside A confer resistance by targeting a cleft significant in side chain binding.

Begaye A, Trostel S, Zhao Z, Taylor RE, Schriemer DC, Sackett DL.

Cell Cycle · research support, n.i.h., intramural; brief-report; journal article · DOI 10.4161/cc.10.19.17706

Bibliografisk träff 2010-09-23

Paclitaxel effects on the proteome of HL-60 promyelocytic leukemic cells: comparison to peloruside A.

Wilmes A, Chan A, Rawson P, William Jordan T, Miller JH.

Invest New Drugs · comparative study; research support, non-u.s. gov't; journal article · DOI 10.1007/s10637-010-9540-1

Bibliografisk träff 2010-01-27

Effects of the microtubule stabilizing agent peloruside A on the proteome of HL-60 cells.

Wilmes A, Rawson P, Peng L, McLauchlan D, Northcote PT, Jordan TW, Miller JH.

Invest New Drugs · research support, non-u.s. gov't; journal article · DOI 10.1007/s10637-010-9387-5

Bibliografisk träff 2002-06-01

Peloruside A, a novel antimitotic agent with paclitaxel-like microtubule- stabilizing activity.

Hood KA, West LM, Rouwé B, Northcote PT, Berridge MV, Wakefield SJ, Miller JH.

Cancer Res · comparative study; research support, non-u.s. gov't; journal article