Secondary metabolites of endophytic fungi isolated from Huperzia serrata.
Cao D, Sun P, Bhowmick S, Wei Y, Guo B, Wei Y, Mur LAJ, Sun Z.
Fitoterapia · review; journal article · DOI 10.1016/j.fitote.2021.104970 PUBLIKATIONSREGISTRET
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32 träffarStructural Fractal Analysis of the Active Site of Acetylcholinesterase in Complexes with Huperzine A, Galantamine, and Donepezil.
Grigorev VY, Rasdolsky AN, Grigoreva LD, Tinkov OV.
Mol Inform · research support, non-u.s. gov't; journal article · DOI 10.1002/minf.202100127<i>In Silico</i>-Guided Rational Drug Design and Semi-synthesis of C(2)-Functionalized Huperzine A Derivatives as Acetylcholinesterase Inhibitors.
Anukanon S, Pongpamorn P, Tiyabhorn W, Chatwichien J, Niwetmarin W, Sessions RB, Ruchirawat S, Thasana N.
ACS Omega · research-article; journal article · DOI 10.1021/acsomega.1c02875Promising tacrine/huperzine A-based dimeric acetylcholinesterase inhibitors for neurodegenerative disorders: From relieving symptoms to modifying diseases through multitarget.
Mak S, Li W, Fu H, Luo J, Cui W, Hu S, Pang Y, Carlier PR, Tsim KW, Pi R, Han Y.
J Neurochem · research support, non-u.s. gov't; research-article; review; journal article · DOI 10.1111/jnc.15379Huperzine A combined with hyperbaric oxygen on the effect on cognitive function and serum hypoxia-inducible factor-1α Level in elderly patients with vascular dementia.
Li J, Meng X, Li F, Liu J, Ma M, Chen W.
Am J Transl Res · research-article; journal articleEffects of the Hydroethanolic Extract of <i>Lycopodium selago</i> L. on Scopolamine-Induced Memory Deficits in Zebrafish.
Valu MV, Ducu C, Moga S, Negrea D, Hritcu L, Boiangiu RS, Vamanu E, Balseanu TA, Carradori S, Soare LC.
Pharmaceuticals (Basel) · research-article; journal article · DOI 10.3390/ph14060568In Vitro Propagation, Huperzine A Content and Antioxidant Activity of Three Genotypic <i>Huperzia serrata</i>.
Yang Y, Dai L, Wu D, Dong L, Tu Y, Xie J, Luo X.
Plants (Basel) · research-article; journal article · DOI 10.3390/plants10061112Simultaneous separation and determination of three huperzine alkaloids in Huperzia serrata and its preparations by cyclodextrin-modified mixed micellar electrokinetic capillary chromatography.
Yang Y, Wang H, Yu H, Zhang H, Zhang G, Chang R, Chen A.
Anal Biochem · research support, non-u.s. gov't; validation study; journal article · DOI 10.1016/j.ab.2021.114207The effects of Huperzine A on dementia and mild cognitive impairment: An overview of systematic reviews.
Ghassab-Abdollahi N, Mobasseri K, Dehghani Ahmadabad A, Nadrian H, Mirghafourvand M.
Phytother Res · review; journal article · DOI 10.1002/ptr.7126Effect of continuous and multi-phasic current profiles on the iontophoretic transport of pramipexole, rasagiline and huperzine A: Depicting temporal variation and biodistribution in the skin.
Singhal M, Serna C, Kalaria D, Kalia YN.
Int J Pharm · journal article · DOI 10.1016/j.ijpharm.2021.120445Endophytic Fungal Community of <i>Huperzia serrata</i>: Diversity and Relevance to the Production of Huperzine A by the Plant Host.
Cui L, Noushahi HA, Zhang Y, Liu J, Cosoveanu A, Liu Y, Yan L, Zhang J, Shu S.
Molecules · research-article; journal article · DOI 10.3390/molecules26040892Huperzine A lowers intraocular pressure via the M3 mAChR and provides retinal neuroprotection via the M1 mAChR: a promising agent for the treatment of glaucoma.
Yu P, Dong WP, Tang YB, Chen HZ, Cui YY, Bian XL.
Ann Transl Med · research-article; journal article · DOI 10.21037/atm-20-8093Response surface methodology-mediated improvement of the irradiated endophytic fungal strain, Alternaria brassicae AGF041 for Huperzine A-hyperproduction.
Zaki AG, El-Shatoury EH, Ahmed AS, Al-Hagar OEA.
Lett Appl Microbiol · journal article · DOI 10.1111/lam.13435Dissolving microneedles for transdermal delivery of huperzine A for the treatment of Alzheimer's disease.
Yan Q, Wang W, Weng J, Zhang Z, Yin L, Yang Q, Guo F, Wang X, Chen F, Yang G.
Drug Deliv · research-article; journal article · DOI 10.1080/10717544.2020.1797240Huperzine A in treatment of amyloid-β-associated neuropathology in a mouse model of Alzheimer disease: abridged secondary publication.
Yuan Q, Lin ZX, Wu W, Albert WN, Zee BCY.
Hong Kong Med J · journal articleHuperzine-A administration recovers rat ovary function after sympathetic stress.
Riquelme R, Ruz F, Mayerhofer A, Lara HE.
J Neuroendocrinol · research support, non-u.s. gov't; journal article · DOI 10.1111/jne.12914Five novel and highly efficient endophytic fungi isolated from Huperzia serrata expressing huperzine A for the treatment of Alzheimer's disease.
Wen-Xia H, Zhong-Wen H, Min J, Han Z, Wei-Ze L, Li-Bin Y, Fei L, Lu H, Ning Z, Xiao-Feng L.
Appl Microbiol Biotechnol · journal article · DOI 10.1007/s00253-020-10894-4Research on endophytic fungi for producing huperzine A on a large-scale.
Sang X, Yang M, Su J.
Crit Rev Microbiol · review; journal article · DOI 10.1080/1040841x.2020.1819771A drug screening toolkit based on the -1 ribosomal frameshifting of SARS-CoV-2.
Chen Y, Tao H, Shen S, Miao Z, Li L, Jia Y, Zhang H, Bai X, Fu X.
Heliyon · research-article; journal article · DOI 10.1016/j.heliyon.2020.e04793Huperzine A inhibits heroin-seeking behaviors induced by cue or heroin priming in rats.
Ma B, Cai Y, Zhang X, Wang F, Zhuang D, Liu H, Liu Y, Zhou W.
Neuroreport · research support, non-u.s. gov't; journal article · DOI 10.1097/wnr.0000000000001498Huperzine A and Huperzine B Production by Prothallus Cultures of <i>Huperzia selago</i> (L.) Bernh. ex Schrank et Mart.
Szypuła WJ, Wileńska B, Misicka A, Pietrosiuk A.
Molecules · research-article; journal article · DOI 10.3390/molecules25143262A novel huperzine A-producing endophytic fungus Fusarium sp. Rsp5.2 isolated from Huperzia serrate.
Le TTM, Hoang ATH, Nguyen NP, Le TTB, Trinh HTT, Vo TTB, Quyen DV.
Biotechnol Lett · journal article · DOI 10.1007/s10529-020-02836-xThe scoop on brain health dietary supplement products containing huperzine A.
Crawford C, Wang YH, Avula B, Bae JY, Khan IA, Deuster PA.
Clin Toxicol (Phila) · journal article · DOI 10.1080/15563650.2020.1713337Combining antioxidant astaxantin and cholinesterase inhibitor huperzine A boosts neuroprotection.
Yang X, Wei HM, Hu GY, Zhao J, Long LN, Li CJ, Zhao ZJ, Zeng HK, Nie H.
Mol Med Rep · research-article; journal article · DOI 10.3892/mmr.2020.10920Huperzine-A, a versatile herb, for the treatment of Alzheimer's disease.
Tsai SJ.
J Chin Med Assoc · comment; editorial · DOI 10.1097/jcma.0000000000000151Huperzine a in the treatment of Alzheimer's disease and vascular dementia: a meta-analysis.
Xing SH, Zhu CX, Zhang R, An L.
Evid Based Complement Alternat Med · research-article; review; journal article · DOI 10.1155/2014/363985Divergent total synthesis of the Lycopodium alkaloids huperzine A, huperzine B, and huperzine U.
Ding R, Fu JG, Xu GQ, Sun BF, Lin GQ.
J Org Chem · research support, non-u.s. gov't; journal article · DOI 10.1021/jo402419hReducing iron in the brain: a novel pharmacologic mechanism of huperzine A in the treatment of Alzheimer's disease.
Huang XT, Qian ZM, He X, Gong Q, Wu KC, Jiang LR, Lu LN, Zhu ZJ, Zhang HY, Yung WH, Ke Y.
Neurobiol Aging · research support, non-u.s. gov't; journal article · DOI 10.1016/j.neurobiolaging.2013.11.004Huperzine A ameliorates damage induced by acute myocardial infarction in rats through antioxidant, anti-apoptotic and anti-inflammatory mechanisms.
Sui X, Gao C.
Int J Mol Med · journal article · DOI 10.3892/ijmm.2013.1546Indentification of huperzine A-producing endophytic fungi isolated from Huperzia serrata.
Dong LH, Fan SW, Ling QZ, Huang BB, Wei ZJ.
World J Microbiol Biotechnol · research support, non-u.s. gov't; journal article · DOI 10.1007/s11274-013-1519-6