Parthenolide enhances dacarbazine activity against melanoma cells.
Koprowska K, Hartman ML, Sztiller-Sikorska M, Czyz ME.
Anticancer Drugs · research support, non-u.s. gov't; journal article · DOI 10.1097/cad.0b013e3283635a04 PUBLIKATIONSREGISTRET
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27 träffarParthenolide inhibits nociception and neurogenic vasodilatation in the trigeminovascular system by targeting the TRPA1 channel.
Materazzi S, Benemei S, Fusi C, Gualdani R, De Siena G, Vastani N, Andersson DA, Trevisan G, Moncelli MR, Wei X, Dussor G, Pollastro F, Patacchini R, Appendino G, Geppetti P, Nassini R.
Pain · research support, non-u.s. gov't; research-article; journal article; research support, n.i.h., extramural · DOI 10.1016/j.pain.2013.08.002Parthenolide complements the cell death-inducing activity of doxorubicin in melanoma cells.
Wozniak M, Szulawska-Mroczek A, Hartman ML, Nejc D, Czyz M.
Anticancer Res · research support, non-u.s. gov't; journal articleParthenolide reduces cell proliferation and prostaglandin E2 [corrected] in human endometriotic stromal cells and inhibits development of endometriosis in the murine model.
Takai E, Taniguchi F, Nakamura K, Uegaki T, Iwabe T, Harada T.
Fertil Steril · research support, non-u.s. gov't; journal article · DOI 10.1016/j.fertnstert.2013.06.028Parthenolide reverses doxorubicin resistance in human lung carcinoma A549 cells by attenuating NF-κB activation and HSP70 up-regulation.
Xin Y, Yin F, Qi S, Shen L, Xu Y, Luo L, Lan L, Yin Z.
Toxicol Lett · research support, non-u.s. gov't; journal article · DOI 10.1016/j.toxlet.2013.06.215Parthenolide from Parthenium integrifolium reduces tumor burden and alleviate cachexia symptoms in the murine CT-26 model of colorectal carcinoma.
Yang Q, Wan L, Zhou Z, Li Y, Yu Q, Liu L, Li B, Guo C.
Phytomedicine · research support, non-u.s. gov't; journal article · DOI 10.1016/j.phymed.2013.04.020Parthenolide: from plant shoots to cancer roots.
Ghantous A, Sinjab A, Herceg Z, Darwiche N.
Drug Discov Today · research support, non-u.s. gov't; review; journal article · DOI 10.1016/j.drudis.2013.05.005Parthenolide induces caspase-independent and AIF-mediated cell death in human osteosarcoma and melanoma cells.
D'Anneo A, Carlisi D, Lauricella M, Emanuele S, Di Fiore R, Vento R, Tesoriere G.
J Cell Physiol · research support, non-u.s. gov't; journal article · DOI 10.1002/jcp.24131Parthenolide eliminates leukemia-initiating cell populations and improves survival in xenografts of childhood acute lymphoblastic leukemia.
Diamanti P, Cox CV, Moppett JP, Blair A.
Blood · research support, non-u.s. gov't; journal article · DOI 10.1182/blood-2012-08-448852Parthenolide reduces the frequency of ABCB5-positive cells and clonogenic capacity of melanoma cells from anchorage independent melanospheres.
Czyz M, Koprowska K, Sztiller-Sikorska M.
Cancer Biol Ther · research support, non-u.s. gov't; research-article; journal article · DOI 10.4161/cbt.22952Apoptosis-mediated cytotoxic effects of parthenolide and the new synthetic analog MZ-6 on two breast cancer cell lines.
Wyrębska A, Szymański J, Gach K, Piekielna J, Koszuk J, Janecki T, Janecka A.
Mol Biol Rep · comparative study; research support, non-u.s. gov't; research-article; journal article · DOI 10.1007/s11033-012-2215-6Parthenolide, a sesquiterpene lactone from the medical herb feverfew, shows anticancer activity against human melanoma cells in vitro.
Lesiak K, Koprowska K, Zalesna I, Nejc D, Düchler M, Czyz M.
Melanoma Res · research support, non-u.s. gov't; journal article · DOI 10.1097/cmr.0b013e328333bbe4Can we predict the effects of NF-kappaB inhibition in sepsis? Studies with parthenolide and ethyl pyruvate.
Li X, Su J, Cui X, Li Y, Barochia A, Eichacker PQ.
Expert Opin Investig Drugs · research support, n.i.h., intramural; research-article; review; journal article · DOI 10.1517/13543780903018880Modulation of DNA methylation by a sesquiterpene lactone parthenolide.
Liu Z, Liu S, Xie Z, Pavlovicz RE, Wu J, Chen P, Aimiuwu J, Pang J, Bhasin D, Neviani P, Fuchs JR, Plass C, Li PK, Li C, Huang TH, Wu LC, Rush L, Wang H, Perrotti D, Marcucci G, Chan KK.
J Pharmacol Exp Ther · research support, non-u.s. gov't; research-article; journal article; research support, n.i.h., extramural · DOI 10.1124/jpet.108.147934The lipophilic hapten parthenolide induces interferon-gamma and interleukin-13 production by peripheral blood-derived CD8+ T cells from contact allergic subjects in vitro.
Wahlkvist H, Masjedi K, Gruvberger B, Zuber B, Karlberg AT, Bruze M, Ahlborg N.
Br J Dermatol · research support, non-u.s. gov't; journal article · DOI 10.1111/j.1365-2133.2007.08287.xParthenolide, a natural inhibitor of Nuclear Factor-kappaB, inhibits lung colonization of murine osteosarcoma cells.
Kishida Y, Yoshikawa H, Myoui A.
Clin Cancer Res · research support, non-u.s. gov't; journal article · DOI 10.1158/1078-0432.ccr-06-1559Parthenolide-induced apoptosis in multiple myeloma cells involves reactive oxygen species generation and cell sensitivity depends on catalase activity.
Wang W, Adachi M, Kawamura R, Sakamoto H, Hayashi T, Ishida T, Imai K, Shinomura Y.
Apoptosis · research support, non-u.s. gov't; journal article · DOI 10.1007/s10495-006-0287-2Parthenolide cooperates with NS398 to inhibit growth of human hepatocellular carcinoma cells through effects on apoptosis and G0-G1 cell cycle arrest.
Ralstin MC, Gage EA, Yip-Schneider MT, Klein PJ, Wiebke EA, Schmidt CM.
Mol Cancer Res · journal article · DOI 10.1158/1541-7786.mcr-05-0157Comparative effects of the herbal constituent parthenolide (Feverfew) on lipopolysaccharide-induced inflammatory gene expression in murine spleen and liver.
Smolinski AT, Pestka JJ.
J Inflamm (Lond) · research-article; journal article · DOI 10.1186/1476-9255-2-6Antileishmanial activity of parthenolide, a sesquiterpene lactone isolated from Tanacetum parthenium.
Tiuman TS, Ueda-Nakamura T, Garcia Cortez DA, Dias Filho BP, Morgado-Díaz JA, de Souza W, Nakamura CV.
Antimicrob Agents Chemother · research support, non-u.s. gov't; research-article; journal article · DOI 10.1128/aac.49.11.176-182.2005Microtubule-interfering activity of parthenolide.
Miglietta A, Bozzo F, Gabriel L, Bocca C.
Chem Biol Interact · research support, non-u.s. gov't; journal article · DOI 10.1016/j.cbi.2004.07.005Parthenolide improves systemic hemodynamics and decreases tissue leukosequestration in rats with polymicrobial sepsis.
Sheehan M, Wong HR, Hake PW, Zingarelli B.
Crit Care Med · comparative study; research support, u.s. gov't, p.h.s.; journal article · DOI 10.1097/01.ccm.0000085186.14867.f7Parthenolide and its photochemically synthesized 1(10)Z isomer: chemical reactivity and structure-activity relationship studies in human leucocyte chemotaxis.
Neukirch H, Kaneider NC, Wiedermann CJ, Guerriero A, D'Ambrosio M.
Bioorg Med Chem · research support, non-u.s. gov't; journal article · DOI 10.1016/s0968-0896(02)00553-9Inhibition of LPS-induced p42/44 MAP kinase activation and iNOS/NO synthesis by parthenolide in rat primary microglial cells.
Fiebich BL, Lieb K, Engels S, Heinrich M.
J Neuroimmunol · research support, non-u.s. gov't; journal article · DOI 10.1016/s0165-5728(02)00279-5Parthenolide, an inhibitor of the nuclear factor-kappaB pathway, ameliorates cardiovascular derangement and outcome in endotoxic shock in rodents.
Sheehan M, Wong HR, Hake PW, Malhotra V, O'Connor M, Zingarelli B.
Mol Pharmacol · research support, u.s. gov't, p.h.s.; journal article · DOI 10.1124/mol.61.5.953Sesquiterpene lactone parthenolide, an inhibitor of IkappaB kinase complex and nuclear factor-kappaB, exerts beneficial effects in myocardial reperfusion injury.
Zingarelli B, Hake PW, Denenberg A, Wong HR.
Shock · research support, u.s. gov't, p.h.s.; journal article · DOI 10.1097/00024382-200202000-00008Inhibition of interleukin-12 production in lipopolysaccharide-activated mouse macrophages by parthenolide, a predominant sesquiterpene lactone in Tanacetum parthenium: involvement of nuclear factor-kappaB.
Kang BY, Chung SW, Kim TS.
Immunol Lett · research support, non-u.s. gov't; journal article · DOI 10.1016/s0165-2478(01)00211-5