Production of proteasome inhibitor syringolin A by the endophyte Rhizobium sp. strain AP16.
Dudnik A, Bigler L, Dudler R.
Appl Environ Microbiol · research support, non-u.s. gov't; research-article; journal article · DOI 10.1128/aem.00395-14 PUBLIKATIONSREGISTRET
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Publikationer i urvalet
11 träffarTotal synthesis of syringolin A and improvement of its biological activity.
Chiba T, Hosono H, Nakagawa K, Asaka M, Takeda H, Matsuda A, Ichikawa S.
Angew Chem Int Ed Engl · research support, non-u.s. gov't; journal article · DOI 10.1002/anie.201402428Proteasome activity imaging and profiling characterizes bacterial effector syringolin A.
Kolodziejek I, Misas-Villamil JC, Kaschani F, Clerc J, Gu C, Krahn D, Niessen S, Verdoes M, Willems LI, Overkleeft HS, Kaiser M, van der Hoorn RA.
Plant Physiol · research support, non-u.s. gov't; journal article · DOI 10.1104/pp.110.163733Pseudomonas syringae virulence factor syringolin A counteracts stomatal immunity by proteasome inhibition.
Schellenberg B, Ramel C, Dudler R.
Mol Plant Microbe Interact · research support, non-u.s. gov't; journal article · DOI 10.1094/mpmi-04-10-0094Total synthesis of syringolin A.
Dai C, Stephenson CR.
Org Lett · research support, non-u.s. gov't; research support, u.s. gov't, non-p.h.s.; journal article · DOI 10.1021/ol101252yTotal synthesis of syringolin A and B.
Pirrung MC, Biswas G, Ibarra-Rivera TR.
Org Lett · research support, non-u.s. gov't; research support, u.s. gov't, non-p.h.s.; journal article · DOI 10.1021/ol100761zSylC catalyzes ureido-bond formation during biosynthesis of the proteasome inhibitor syringolin A.
Imker HJ, Walsh CT, Wuest WM.
J Am Chem Soc · research-article; journal article; research support, n.i.h., extramural · DOI 10.1021/ja909170uSyringolin A selectively labels the 20 S proteasome in murine EL4 and wild-type and bortezomib-adapted leukaemic cell lines.
Clerc J, Florea BI, Kraus M, Groll M, Huber R, Bachmann AS, Dudler R, Driessen C, Overkleeft HS, Kaiser M.
Chembiochem · research support, non-u.s. gov't; journal article · DOI 10.1002/cbic.200900411Biosynthesis of the proteasome inhibitor syringolin A: the ureido group joining two amino acids originates from bicarbonate.
Ramel C, Tobler M, Meyer M, Bigler L, Ebert MO, Schellenberg B, Dudler R.
BMC Biochem · research support, non-u.s. gov't; research-article; journal article · DOI 10.1186/1471-2091-10-26A plant pathogen virulence factor inhibits the eukaryotic proteasome by a novel mechanism.
Groll M, Schellenberg B, Bachmann AS, Archer CR, Huber R, Powell TK, Lindow S, Kaiser M, Dudler R.
Nature · research support, non-u.s. gov't; journal article · DOI 10.1038/nature06782Syringolin A, a new plant elicitor from the phytopathogenic bacterium Pseudomonas syringae pv. syringae, inhibits the proliferation of neuroblastoma and ovarian cancer cells and induces apoptosis.
Coleman CS, Rocetes JP, Park DJ, Wallick CJ, Warn-Cramer BJ, Michel K, Dudler R, Bachmann AS.
Cell Prolif · research support, non-u.s. gov't; research-article; journal article; research support, n.i.h., extramural · DOI 10.1111/j.1365-2184.2006.00402.x