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Publikationer i urvalet

12 träffar

Bibliografisk träff 2011-02-22

14-Aminocamptothecins: their synthesis, preclinical activity, and potential use for cancer treatment.

Duan JX, Cai X, Meng F, Sun JD, Liu Q, Jung D, Jiao H, Matteucci J, Jung B, Bhupathi D, Ahluwalia D, Huang H, Hart CP, Matteucci M.

J Med Chem · journal article · DOI 10.1021/jm101354u

Bibliografisk träff 2008-04-21

Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.

Obach RS, Lombardo F, Waters NJ.

Drug Metab Dispos · journal article · DOI 10.1124/dmd.108.020479

Bibliografisk träff 2004-08-01

Cytotoxic pyrroloiminoquinones from four new species of South African latrunculid sponges.

Antunes EM, Beukes DR, Kelly M, Samaai T, Barrows LR, Marshall KM, Sincich C, Davies-Coleman MT.

J Nat Prod · research support, non-u.s. gov't; journal article · DOI 10.1021/np034084b

Bibliografisk träff 2003-06-01

Differential effects of the breast cancer resistance protein on the cellular accumulation and cytotoxicity of 9-aminocamptothecin and 9-nitrocamptothecin.

Rajendra R, Gounder MK, Saleem A, Schellens JH, Ross DD, Bates SE, Sinko P, Rubin EH.

Cancer Res · research support, u.s. gov't, p.h.s.; research support, u.s. gov't, non-p.h.s.; journal article

Bibliografisk träff 2002-09-01

Novel 20-carbonate linked prodrugs of camptothecin and 9-aminocamptothecin designed for activation by tumour-associated plasmin.

de Groot FM, Busscher GF, Aben RW, Scheeren HW.

Bioorg Med Chem Lett · journal article · DOI 10.1016/s0960-894x(02)00388-8

Bibliografisk träff 2001-04-01

Circumvention of breast cancer resistance protein (BCRP)-mediated resistance to camptothecins in vitro using non-substrate drugs or the BCRP inhibitor GF120918.

Maliepaard M, van Gastelen MA, Tohgo A, Hausheer FH, van Waardenburg RC, de Jong LA, Pluim D, Beijnen JH, Schellens JH.

Clin Cancer Res · research support, non-u.s. gov't; journal article

Bibliografisk träff 1999-09-01

Design and synthesis of water-soluble glucuronide derivatives of camptothecin for cancer prodrug monotherapy and antibody-directed enzyme prodrug therapy (ADEPT).

Leu YL, Roffler SR, Chern JW.

J Med Chem · research support, non-u.s. gov't; journal article · DOI 10.1021/jm990124q

Bibliografisk träff 1994-01-01

The structural basis of camptothecin interactions with human serum albumin: impact on drug stability.

Burke TG, Mi Z.

J Med Chem · comparative study; research support, u.s. gov't, p.h.s.; research support, non-u.s. gov't; journal article · DOI 10.1021/jm00027a005

Bibliografisk träff 1993-09-01

Plant antitumor agents. 30. Synthesis and structure activity of novel camptothecin analogs.

Wall ME, Wani MC, Nicholas AW, Manikumar G, Tele C, Moore L, Truesdale A, Leitner P, Besterman JM.

J Med Chem · comparative study; research support, u.s. gov't, p.h.s.; research support, non-u.s. gov't; journal article · DOI 10.1021/jm00070a013

Bibliografisk träff 1991-01-01

Synthesis of water-soluble (aminoalkyl)camptothecin analogues: inhibition of topoisomerase I and antitumor activity.

Kingsbury WD, Boehm JC, Jakas DR, Holden KG, Hecht SM, Gallagher G, Caranfa MJ, McCabe FL, Faucette LF, Johnson RK.

J Med Chem · comparative study; research support, u.s. gov't, p.h.s.; journal article · DOI 10.1021/jm00105a017

Bibliografisk träff 1987-10-01

Plant antitumor agents. 25. Total synthesis and antileukemic activity of ring A substituted camptothecin analogues. Structure-activity correlations.

Wani MC, Nicholas AW, Manikumar G, Wall ME.

J Med Chem · research support, u.s. gov't, p.h.s.; journal article · DOI 10.1021/jm00393a016

Bibliografisk träff 1986-11-01

Plant antitumor agents. 23. Synthesis and antileukemic activity of camptothecin analogues.

Wani MC, Nicholas AW, Wall ME.

J Med Chem · research support, u.s. gov't, p.h.s.; journal article · DOI 10.1021/jm00161a035