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Publikationer i urvalet

7 träffar

Bibliografisk träff 2024-01-13

Identification and evaluation of small-molecule inhibitors against the dNTPase SAMHD1 via a comprehensive screening funnel.

Zhang SM, Paulin CBJ, Shu H, Yagüe-Capilla M, Michel M, Marttila P, Ortis F, Bwanika HC, Dirks C, Venkatram RP, Wiita E, Jemth AS, Almlöf I, Loseva O, Hormann FM, Koolmeister T, Linde E, Lee S, Llona-Minguez S, Haraldsson M, Axelsson H, Strömberg K, Homan EJ, Scobie M, Lundbäck T, Helleday T, Rudd SG.

iScience · research-article; journal article · DOI 10.1016/j.isci.2024.108907

Bibliografisk träff 2023-07-19

A preclinical secondary pharmacology resource illuminates target-adverse drug reaction associations of marketed drugs.

Sutherland JJ, Yonchev D, Fekete A, Urban L.

Nat Commun · research support, non-u.s. gov't; research-article; journal article · DOI 10.1038/s41467-023-40064-9

Bibliografisk träff 2012-09-07

Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification.

Warner DJ, Chen H, Cantin LD, Kenna JG, Stahl S, Walker CL, Noeske T.

Drug Metab Dispos · journal article · DOI 10.1124/dmd.112.047068

Bibliografisk träff 2003-08-01

Topological virtual screening: a way to find new anticonvulsant drugs from chemical diversity.

Bruno-Blanch L, Gálvez J, García-Domenech R.

Bioorg Med Chem Lett · research support, non-u.s. gov't; journal article · DOI 10.1016/s0960-894x(03)00535-3

Bibliografisk träff 1984-05-01

Phosphorus analogues of gamma-aminobutyric acid, a new class of anticonvulsants.

Cates LA, Li VS, Yakshe CC, Fadeyi MO, Andree TH, Karbon EW, Enna SJ.

J Med Chem · comparative study; research support, u.s. gov't, p.h.s.; research support, non-u.s. gov't; research support, u.s. gov't, non-p.h.s.; journal article · DOI 10.1021/jm00371a017

Bibliografisk träff 1983-10-01

Synthesis of aminomethyl-substituted cyclic imide derivatives for evaluation as anticonvulsants.

Stratford ES, Curley RW.

J Med Chem · research support, u.s. gov't, p.h.s.; journal article · DOI 10.1021/jm00364a020

Bibliografisk träff 1977-03-01

Potential long-acting anticonvulsants. 1; Synthesis and activity of succinimides containing an alkylating group at the 2 position.

Kornet MJ, Crider AM, Magarian EO.

J Med Chem · comparative study; journal article · DOI 10.1021/jm00213a018