Antifungal activity of hypothemycin against Peronophythora litchii in vitro and in vivo.
Xu L, Xue J, Wu P, Wang D, Lin L, Jiang Y, Duan X, Wei X.
J Agric Food Chem · research support, non-u.s. gov't; journal article · DOI 10.1021/jf4030882 PUBLIKATIONSREGISTRET
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Publikationer i urvalet
11 träffarHypothemycin, a fungal natural product, identifies therapeutic targets in Trypanosoma brucei [corrected].
Nishino M, Choy JW, Gushwa NN, Oses-Prieto JA, Koupparis K, Burlingame AL, Renslo AR, McKerrow JH, Taunton J.
Elife · research-article; validation study; journal article; research support, n.i.h., extramural · DOI 10.7554/elife.00712Solid-state circular dichroism and hydrogen bonding, part 2: the case of hypothemycin re-investigated.
Pescitelli G.
Chirality · journal article · DOI 10.1002/chir.22008Enzymatic synthesis of resorcylic acid lactones by cooperation of fungal iterative polyketide synthases involved in hypothemycin biosynthesis.
Zhou H, Qiao K, Gao Z, Meehan MJ, Li JW, Zhao X, Dorrestein PC, Vederas JC, Tang Y.
J Am Chem Soc · research support, non-u.s. gov't; research-article; journal article; research support, n.i.h., extramural · DOI 10.1021/ja100060kThe resorcylic acid lactone hypothemycin selectively inhibits the mitogen-activated protein kinase kinase-extracellular signal-regulated kinase pathway in cells.
Fukazawa H, Ikeda Y, Fukuyama M, Suzuki T, Hori H, Okuda T, Uehara Y.
Biol Pharm Bull · comparative study; research support, non-u.s. gov't; journal article · DOI 10.1248/bpb.33.168Divergent syntheses of resorcylic acid lactones: L-783277, LL-Z1640-2, and hypothemycin.
Dakas PY, Jogireddy R, Valot G, Barluenga S, Winssinger N.
Chemistry · research support, non-u.s. gov't; journal article · DOI 10.1002/chem.200901373Genes for the biosynthesis of the fungal polyketides hypothemycin from Hypomyces subiculosus and radicicol from Pochonia chlamydosporia.
Reeves CD, Hu Z, Reid R, Kealey JT.
Appl Environ Microbiol · research-article; journal article · DOI 10.1128/aem.00478-08Semisynthesis and cytotoxicity of hypothemycin analogues.
Hearn BR, Sundermann K, Cannoy J, Santi DV.
ChemMedChem · journal article · DOI 10.1002/cmdc.200700128Hypothemycin inhibits the proliferative response and modulates the production of cytokines during T cell activation.
Camacho R, Staruch MJ, DaSilva C, Koprak S, Sewell T, Salituro G, Dumont FJ.
Immunopharmacology · journal article · DOI 10.1016/s0162-3109(99)00085-5Antitumor efficacy of hypothemycin, a new Ras-signaling inhibitor.
Tanaka H, Nishida K, Sugita K, Yoshioka T.
Jpn J Cancer Res · research-article; journal article · DOI 10.1111/j.1349-7006.1999.tb00688.xSuppression of oncogenic transformation by hypothemycin associated with accelerated cyclin D1 degradation through ubiquitin-proteasome pathway.
Sonoda H, Omi K, Hojo K, Nishida K, Omura S, Sugita K.
Life Sci · journal article · DOI 10.1016/s0024-3205(99)00259-3