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Publikationer i urvalet

6 träffar

Bibliografisk träff 2015-09-14

GITR subverts Foxp3(+) Tregs to boost Th9 immunity through regulation of histone acetylation.

Xiao X, Shi X, Fan Y, Zhang X, Wu M, Lan P, Minze L, Fu YX, Ghobrial RM, Liu W, Li XC.

Nat Commun · research-article; journal article; research support, n.i.h., extramural · DOI 10.1038/ncomms9266

Bibliografisk träff 2015-07-01

Galectin-9 in Combination With EX-527 Prolongs the Survival of Cardiac Allografts in Mice After Cardiac Transplantation.

Tao YF, Lin F, Yan XY, Gao XG, Teng F, Fu ZR, Wang ZX.

Transplant Proc · research support, non-u.s. gov't; journal article · DOI 10.1016/j.transproceed.2015.04.091

Bibliografisk träff 2015-03-01

An exploratory double-blind, randomized clinical trial with selisistat, a SirT1 inhibitor, in patients with Huntington's disease.

Süssmuth SD, Haider S, Landwehrmeyer GB, Farmer R, Frost C, Tripepi G, Andersen CA, Di Bacco M, Lamanna C, Diodato E, Massai L, Diamanti D, Mori E, Magnoni L, Dreyhaupt J, Schiefele K, Craufurd D, Saft C, Rudzinska M, Ryglewicz D, Orth M, Brzozy S, Baran A, Pollio G, Andre R, Tabrizi SJ, Darpo B, Westerberg G, PADDINGTON Consortium.

Br J Clin Pharmacol · research support, non-u.s. gov't; research-article; multicenter study; randomized controlled trial; journal article · DOI 10.1111/bcp.12512

Bibliografisk träff 2015-03-01

Safety, pharmacokinetics, pharmacogenomics and QT concentration-effect modelling of the SirT1 inhibitor selisistat in healthy volunteers.

Westerberg G, Chiesa JA, Andersen CA, Diamanti D, Magnoni L, Pollio G, Darpo B, Zhou M.

Br J Clin Pharmacol · research-article; randomized controlled trial; journal article · DOI 10.1111/bcp.12513

Bibliografisk träff 2014-08-05

Sirtuin inhibitor Ex-527 causes neural tube defects, ventral edema formations, and gastrointestinal malformations in Xenopus laevis embryos.

Ohata Y, Matsukawa S, Moriyama Y, Michiue T, Morimoto K, Sato Y, Kuroda H.

Dev Growth Differ · journal article · DOI 10.1111/dgd.12145

Bibliografisk träff 2013-07-09

Ex-527 inhibits Sirtuins by exploiting their unique NAD+-dependent deacetylation mechanism.

Gertz M, Fischer F, Nguyen GT, Lakshminarasimhan M, Schutkowski M, Weyand M, Steegborn C.

Proc Natl Acad Sci U S A · research support, non-u.s. gov't; research-article; journal article · DOI 10.1073/pnas.1303628110