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Publikationer i urvalet

11 träffar

Bibliografisk träff 2015-08-17

Cardiotoxin III Inhibits Hepatocyte Growth Factor-Induced Epithelial-Mesenchymal Transition and Suppresses Invasion of MDA-MB-231 Cells.

Tsai PC, Fu YS, Chang LS, Lin SR.

J Biochem Mol Toxicol · research support, non-u.s. gov't; journal article · DOI 10.1002/jbt.21735

Bibliografisk träff 2014-05-04

MET inhibitor PHA-665752 suppresses the hepatocyte growth factor-induced cell proliferation and radioresistance in nasopharyngeal carcinoma cells.

Liu T, Li Q, Sun Q, Zhang Y, Yang H, Wang R, Chen L, Wang W.

Biochem Biophys Res Commun · research support, non-u.s. gov't; journal article · DOI 10.1016/j.bbrc.2014.04.147

Bibliografisk träff 2013-05-07

Celastrol exerts synergistic effects with PHA-665752 and inhibits tumor growth of c-Met-deficient hepatocellular carcinoma in vivo.

Jiang HL, Jin JZ, Wu D, Xu D, Lin GF, Yu H, Ma DY, Liang J.

Mol Biol Rep · journal article · DOI 10.1007/s11033-013-2501-y

Bibliografisk träff 2011-05-09

MET inhibition in tumor cells by PHA665752 impairs homologous recombination repair of DNA double strand breaks.

Medová M, Aebersold DM, Zimmer Y.

Int J Cancer · research support, non-u.s. gov't; journal article · DOI 10.1002/ijc.26058

Bibliografisk träff 2010-09-01

Molecular predictors of sensitivity to the MET inhibitor PHA665752 in lung carcinoma cells.

Matsubara D, Ishikawa S, Oguni S, Aburatani H, Fukayama M, Niki T.

J Thorac Oncol · research support, non-u.s. gov't; journal article · DOI 10.1097/jto.0b013e3181e2a409

Bibliografisk träff 2009-11-25

PHA665752, a small-molecule inhibitor of c-Met, inhibits hepatocyte growth factor-stimulated migration and proliferation of c-Met-positive neuroblastoma cells.

Crosswell HE, Dasgupta A, Alvarado CS, Watt T, Christensen JG, De P, Durden DL, Findley HW.

BMC Cancer · research support, non-u.s. gov't; research-article; journal article; research support, n.i.h., extramural · DOI 10.1186/1471-2407-9-411

Bibliografisk träff 2008-08-01

Small molecule c-MET inhibitor PHA665752: effect on cell growth and motility in papillary thyroid carcinoma.

Chattopadhyay C, El-Naggar AK, Williams MD, Clayman GL.

Head Neck · research support, non-u.s. gov't; journal article; research support, n.i.h., extramural · DOI 10.1002/hed.20816

Bibliografisk träff 2008-04-01

A selective small molecule inhibitor of c-Met, PHA-665752, reverses lung premalignancy induced by mutant K-ras.

Yang Y, Wislez M, Fujimoto N, Prudkin L, Izzo JG, Uno F, Ji L, Hanna AE, Langley RR, Liu D, Johnson FM, Wistuba I, Kurie JM.

Mol Cancer Ther · research-article; journal article; research support, n.i.h., extramural · DOI 10.1158/1535-7163.mct-07-2045

Bibliografisk träff 2007-04-01

A selective small molecule inhibitor of c-Met, PHA665752, inhibits tumorigenicity and angiogenesis in mouse lung cancer xenografts.

Puri N, Khramtsov A, Ahmed S, Nallasura V, Hetzel JT, Jagadeeswaran R, Karczmar G, Salgia R.

Cancer Res · research support, non-u.s. gov't; journal article; research support, n.i.h., extramural · DOI 10.1158/0008-5472.can-06-4416

Bibliografisk träff 2006-02-06

Amplification of MET may identify a subset of cancers with extreme sensitivity to the selective tyrosine kinase inhibitor PHA-665752.

Smolen GA, Sordella R, Muir B, Mohapatra G, Barmettler A, Archibald H, Kim WJ, Okimoto RA, Bell DW, Sgroi DC, Christensen JG, Settleman J, Haber DA.

Proc Natl Acad Sci U S A · research support, non-u.s. gov't; research-article; journal article; research support, n.i.h., extramural · DOI 10.1073/pnas.0508776103

Bibliografisk träff 2005-03-01

A selective small molecule c-MET Inhibitor, PHA665752, cooperates with rapamycin.

Ma PC, Schaefer E, Christensen JG, Salgia R.

Clin Cancer Res · research support, u.s. gov't, p.h.s.; research support, non-u.s. gov't; journal article; research support, n.i.h., extramural · DOI 10.1158/1078-0432.ccr-04-1708