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Publikationer i urvalet

11 träffar

Bibliografisk träff 2015-10-09

Genome-wide analysis of differentially expressed miRNA in PLX4720-resistant and parental human thyroid cancer cell lines.

Varmeh S, Vanden Borre P, Gunda V, Brauner E, Holm T, Wang Y, Sadreyev RI, Parangi S.

Surgery · research support, non-u.s. gov't; research-article; journal article; research support, n.i.h., extramural · DOI 10.1016/j.surg.2015.06.046

Bibliografisk träff 2015-09-07

B-Raf inhibition in conjunctival melanoma cell lines with PLX 4720.

Riechardt AI, Maier AK, Nonnenmacher A, Reichhart N, Keilholz U, Kociok N, Strauss O, Joussen AM, Gundlach E.

Br J Ophthalmol · research support, non-u.s. gov't; journal article · DOI 10.1136/bjophthalmol-2015-306689

Bibliografisk träff 2014-12-29

Mutated BRAF Emerges as a Major Effector of Recurrence in a Murine Melanoma Model After Treatment With Immunomodulatory Agents.

Zaidi S, Blanchard M, Shim K, Ilett E, Rajani K, Parrish C, Boisgerault N, Kottke T, Thompson J, Celis E, Pulido J, Selby P, Pandha H, Melcher A, Harrington K, Vile R.

Mol Ther · research support, non-u.s. gov't; research-article; journal article; research support, n.i.h., extramural · DOI 10.1038/mt.2014.253

Bibliografisk träff 2014-01-01

Differential effects of the oncogenic BRAF inhibitor PLX4032 (vemurafenib) and its progenitor PLX4720 on ABCB1 function.

Michaelis M, Rothweiler F, Nerreter T, Van Rikxoort M, Sharifi M, Wiese M, Ghafourian T, Cinatl J.

J Pharm Pharm Sci · research support, non-u.s. gov't; journal article · DOI 10.18433/j3tw24

Bibliografisk träff 2012-09-02

Differential inhibitory effects of two Raf-targeting drugs, sorafenib and PLX4720, on the growth of multidrug-resistant cells.

Eum KH, Ahn SK, Kang H, Lee M.

Mol Cell Biochem · research support, non-u.s. gov't; journal article · DOI 10.1007/s11010-012-1446-0

Bibliografisk träff 2012-08-03

BH3-only protein silencing contributes to acquired resistance to PLX4720 in human melanoma.

Shao Y, Aplin AE.

Cell Death Differ · research-article; journal article; research support, n.i.h., extramural · DOI 10.1038/cdd.2012.94

Bibliografisk träff 2011-06-27

Selective BRAFV600E inhibitor PLX4720, requires TRAIL assistance to overcome oncogenic PIK3CA resistance.

Oikonomou E, Koc M, Sourkova V, Andera L, Pintzas A.

PLoS One · research support, non-u.s. gov't; research-article; journal article · DOI 10.1371/journal.pone.0021632

Bibliografisk träff 2011-02-25

Targeting BRAFV600E with PLX4720 displays potent antimigratory and anti-invasive activity in preclinical models of human thyroid cancer.

Nucera C, Nehs MA, Nagarkatti SS, Sadow PM, Mekel M, Fischer AH, Lin PS, Bollag GE, Lawler J, Hodin RA, Parangi S.

Oncologist · research support, non-u.s. gov't; research-article; journal article; research support, n.i.h., extramural · DOI 10.1634/theoncologist.2010-0317

Bibliografisk träff 2010-12-01

Thyroidectomy with neoadjuvant PLX4720 extends survival and decreases tumor burden in an orthotopic mouse model of anaplastic thyroid cancer.

Nehs MA, Nagarkatti S, Nucera C, Hodin RA, Parangi S.

Surgery · research-article; journal article; research support, n.i.h., extramural · DOI 10.1016/j.surg.2010.09.001

Bibliografisk träff 2010-11-18

MEK-independent survival of B-RAFV600E melanoma cells selected for resistance to apoptosis induced by the RAF inhibitor PLX4720.

Jiang CC, Lai F, Thorne RF, Yang F, Liu H, Hersey P, Zhang XD.

Clin Cancer Res · research support, non-u.s. gov't; journal article · DOI 10.1158/1078-0432.ccr-10-2225

Bibliografisk träff 2010-09-06

Hyperactivation of MEK-ERK1/2 signaling and resistance to apoptosis induced by the oncogenic B-RAF inhibitor, PLX4720, in mutant N-RAS melanoma cells.

Kaplan FM, Shao Y, Mayberry MM, Aplin AE.

Oncogene · research support, non-u.s. gov't; research-article; journal article; research support, n.i.h., extramural · DOI 10.1038/onc.2010.408