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Publikationer som ChEBI hänvisar till för torin 2. Visa hela publikationsregistret

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Publikationer i urvalet

11 träffar

Bibliografisk träff 2016-01-01

Torin2 Potentiates Anticancer Effects on Adult T-Cell Leukemia/Lymphoma by Inhibiting Mammalian Target of Rapamycin.

Watanabe T, Sato A, Kobayashi-Watanabe N, Sueoka-Aragane N, Kimura S, Sueoka E.

Anticancer Res · comparative study; research support, non-u.s. gov't; journal article

Bibliografisk träff 2015-07-23

The novel mTOR inhibitor Torin-2 induces autophagy and downregulates the expression of UHRF1 to suppress hepatocarcinoma cell growth.

Wang C, Wang X, Su Z, Fei H, Liu X, Pan Q.

Oncol Rep · journal article · DOI 10.3892/or.2015.4146

Bibliografisk träff 2015-07-01

Torin2 targets dysregulated pathways in anaplastic thyroid cancer and inhibits tumor growth and metastasis.

Sadowski SM, Boufraqech M, Zhang L, Mehta A, Kapur P, Zhang Y, Li Z, Shen M, Kebebew E.

Oncotarget · research support, n.i.h., intramural; research-article; journal article · DOI 10.18632/oncotarget.3833

Bibliografisk träff 2015-05-26

Dual Targeting of mTOR Activity with Torin2 Potentiates Anticancer Effects of Cisplatin in Epithelial Ovarian Cancer.

Hussain AR, Al-Romaizan M, Ahmed M, Thangavel S, Al-Dayel F, Beg S, Uddin S, Siraj AK, Al-Kuraya KS.

Mol Med · research support, non-u.s. gov't; research-article; journal article · DOI 10.2119/molmed.2014.00238

Bibliografisk träff 2014-10-01

Activity of the novel mTOR inhibitor Torin-2 in B-precursor acute lymphoblastic leukemia and its therapeutic potential to prevent Akt reactivation.

Simioni C, Cani A, Martelli AM, Zauli G, Tabellini G, McCubrey J, Capitani S, Neri LM.

Oncotarget · research support, non-u.s. gov't; research-article; journal article · DOI 10.18632/oncotarget.2490

Bibliografisk träff 2014-05-06

mTORC1 and JNK coordinate phosphorylation of the p70S6K1 autoinhibitory domain in skeletal muscle following functional overloading.

Martin TD, Dennis MD, Gordon BS, Kimball SR, Jefferson LS.

Am J Physiol Endocrinol Metab · research-article; journal article; research support, n.i.h., extramural · DOI 10.1152/ajpendo.00064.2014

Bibliografisk träff 2014-03-25

Interleukin-6 secretion by astrocytes is dynamically regulated by PI3K-mTOR-calcium signaling.

Codeluppi S, Fernandez-Zafra T, Sandor K, Kjell J, Liu Q, Abrams M, Olson L, Gray NS, Svensson CI, Uhlén P.

PLoS One · research support, non-u.s. gov't; research-article; journal article · DOI 10.1371/journal.pone.0092649

Bibliografisk träff 2014-02-28

High prevalence of mTOR complex activity can be targeted using Torin2 in papillary thyroid carcinoma.

Ahmed M, Hussain AR, Bavi P, Ahmed SO, Al Sobhi SS, Al-Dayel F, Uddin S, Al-Kuraya KS.

Carcinogenesis · journal article · DOI 10.1093/carcin/bgu051

Bibliografisk träff 2014-02-14

Inactivation of mTor arrests bovine oocytes in the metaphase-I stage, despite reversible inhibition of 4E-BP1 phosphorylation.

Mayer S, Wrenzycki C, Tomek W.

Mol Reprod Dev · research support, non-u.s. gov't; journal article · DOI 10.1002/mrd.22305

Bibliografisk träff 2013-05-01

mTOR kinase structure, mechanism and regulation.

Yang H, Rudge DG, Koos JD, Vaidialingam B, Yang HJ, Pavletich NP.

Nature · research support, non-u.s. gov't; research-article; journal article · DOI 10.1038/nature12122

Bibliografisk träff 2013-02-22

Characterization of Torin2, an ATP-competitive inhibitor of mTOR, ATM, and ATR.

Liu Q, Xu C, Kirubakaran S, Zhang X, Hur W, Liu Y, Kwiatkowski NP, Wang J, Westover KD, Gao P, Ercan D, Niepel M, Thoreen CC, Kang SA, Patricelli MP, Wang Y, Tupper T, Altabef A, Kawamura H, Held KD, Chou DM, Elledge SJ, Janne PA, Wong KK, Sabatini DM, Gray NS.

Cancer Res · research support, non-u.s. gov't; research-article; journal article; research support, n.i.h., extramural · DOI 10.1158/0008-5472.can-12-1702