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Publikationer i urvalet

24 träffar

Bibliografisk träff 2016-03-01

Cariprazine in the treatment of schizophrenia: a proof-of-concept trial.

Durgam S, Litman RE, Papadakis K, Li D, Németh G, Laszlovszky I.

Int Clin Psychopharmacol · research support, non-u.s. gov't; research-article; multicenter study; randomized controlled trial; journal article · DOI 10.1097/yic.0000000000000110

Bibliografisk träff 2015-12-11

The dopamine D₃-preferring D₂/D₃ dopamine receptor partial agonist, cariprazine, reverses behavioural changes in a rat neurodevelopmental model for schizophrenia.

Watson DJG, King MV, Gyertyán I, Kiss B, Adham N, Fone KCF.

Eur Neuropsychopharmacol · research support, non-u.s. gov't; journal article · DOI 10.1016/j.euroneuro.2015.12.020

Bibliografisk träff 2015-12-01

Cariprazine in acute exacerbation of schizophrenia: a fixed-dose, phase 3, randomized, double-blind, placebo- and active-controlled trial.

Durgam S, Cutler AJ, Lu K, Migliore R, Ruth A, Laszlovszky I, Németh G, Meltzer HY.

J Clin Psychiatry · clinical trial, phase iii; research support, non-u.s. gov't; multicenter study; randomized controlled trial; journal article · DOI 10.4088/jcp.15m09997

Bibliografisk träff 2015-11-19

Effects of cariprazine, a novel antipsychotic, on cognitive deficit and negative symptoms in a rodent model of schizophrenia symptomatology.

Neill JC, Grayson B, Kiss B, Gyertyán I, Ferguson P, Adham N.

Eur Neuropsychopharmacol · research support, non-u.s. gov't; journal article · DOI 10.1016/j.euroneuro.2015.11.016

Bibliografisk träff 2015-11-06

An 8-Week Randomized, Double-Blind, Placebo-Controlled Evaluation of the Safety and Efficacy of Cariprazine in Patients With Bipolar I Depression.

Durgam S, Earley W, Lipschitz A, Guo H, Laszlovszky I, Németh G, Vieta E, Calabrese JR, Yatham LN.

Am J Psychiatry · research support, non-u.s. gov't; multicenter study; randomized controlled trial; journal article · DOI 10.1176/appi.ajp.2015.15020164

Bibliografisk träff 2015-11-02

New developments in the management of schizophrenia and bipolar disorder: potential use of cariprazine.

Werner FM, Coveñas R.

Ther Clin Risk Manag · review-article; review; journal article · DOI 10.2147/tcrm.s64915

Bibliografisk träff 2015-11-01

Cariprazine: First Global Approval.

McCormack PL.

Drugs · journal article · DOI 10.1007/s40265-015-0494-7

Bibliografisk träff 2015-10-16

[Psychopharmacology of anxiety and depression: Historical aspects, current treatments and perspectives].

Javelot H.

Ann Pharm Fr · review; journal article · DOI 10.1016/j.pharma.2015.09.001

Bibliografisk träff 2015-09-05

Effect of cariprazine across the symptoms of mania in bipolar I disorder: Analyses of pooled data from phase II/III trials.

Vieta E, Durgam S, Lu K, Ruth A, Debelle M, Zukin S.

Eur Neuropsychopharmacol · clinical trial, phase iii; clinical trial, phase ii; research support, non-u.s. gov't; multicenter study; randomized controlled trial; journal article · DOI 10.1016/j.euroneuro.2015.08.020

Bibliografisk träff 2015-08-01

Efficacy and Safety of Cariprazine in Acute Exacerbation of Schizophrenia: Results From an International, Phase III Clinical Trial.

Kane JM, Zukin S, Wang Y, Lu K, Ruth A, Nagy K, Laszlovszky I, Durgam S.

J Clin Psychopharmacol · clinical trial, phase iii; research support, non-u.s. gov't; multicenter study; randomized controlled trial; journal article · DOI 10.1097/jcp.0000000000000346

Bibliografisk träff 2015-06-27

Cariprazine delays ouabain-evoked epileptiform spikes and loss of activity in rat hippocampal slices.

El-Mallakh RS, Payne RS, Schurr A, Gao Y, Lei Z, Kiss B, Gyertyán I, Adham N.

Psychiatry Res · research support, non-u.s. gov't; journal article · DOI 10.1016/j.psychres.2015.05.114

Bibliografisk träff 2015-03-01

Efficacy and safety of low- and high-dose cariprazine in acute and mixed mania associated with bipolar I disorder: a double-blind, placebo-controlled study.

Calabrese JR, Keck PE, Starace A, Lu K, Ruth A, Laszlovszky I, Németh G, Durgam S.

J Clin Psychiatry · clinical trial, phase iii; research support, non-u.s. gov't; multicenter study; randomized controlled trial; journal article · DOI 10.4088/jcp.14m09081

Bibliografisk träff 2015-01-01

Serotonin 5-HT1A Receptors and Antipsychotics - An Update in Light of New Concepts and Drugs.

McCreary AC, Newman-Tancredi A.

Curr Pharm Des · review; journal article · DOI 10.2174/1381612821666150605105215

Bibliografisk träff 2014-12-02

Cariprazine exerts antimanic properties and interferes with dopamine D2 receptor β-arrestin interactions.

Gao Y, Peterson S, Masri B, Hougland MT, Adham N, Gyertyán I, Kiss B, Caron MG, El-Mallakh RS.

Pharmacol Res Perspect · research-article; journal article · DOI 10.1002/prp2.73

Bibliografisk träff 2014-11-24

Cariprazine in the treatment of acute mania in bipolar I disorder: a double-blind, placebo-controlled, phase III trial.

Sachs GS, Greenberg WM, Starace A, Lu K, Ruth A, Laszlovszky I, Németh G, Durgam S.

J Affect Disord · clinical trial, phase iii; research support, non-u.s. gov't; randomized controlled trial; journal article · DOI 10.1016/j.jad.2014.11.018

Bibliografisk träff 2014-09-01

Attenuation of anhedonia by cariprazine in the chronic mild stress model of depression.

Papp M, Gruca P, Lasoń-Tyburkiewicz M, Adham N, Kiss B, Gyertyán I.

Behav Pharmacol · comparative study; research support, non-u.s. gov't; journal article · DOI 10.1097/fbp.0000000000000070

Bibliografisk träff 2014-07-24

The efficacy and tolerability of cariprazine in acute mania associated with bipolar I disorder: a phase II trial.

Durgam S, Starace A, Li D, Migliore R, Ruth A, Németh G, Laszlovszky I.

Bipolar Disord · research support, non-u.s. gov't; multicenter study; randomized controlled trial; journal article · DOI 10.1111/bdi.12238

Bibliografisk träff 2014-06-30

Safety of antipsychotic drugs: focus on therapeutic and adverse effects.

Werner FM, Coveñas R.

Expert Opin Drug Saf · review; journal article · DOI 10.1517/14740338.2014.935761

Bibliografisk träff 2014-01-10

An evaluation of the safety and efficacy of cariprazine in patients with acute exacerbation of schizophrenia: a phase II, randomized clinical trial.

Durgam S, Starace A, Li D, Migliore R, Ruth A, Németh G, Laszlovszky I.

Schizophr Res · clinical trial, phase ii; research support, non-u.s. gov't; multicenter study; randomized controlled trial; journal article · DOI 10.1016/j.schres.2013.11.041

Bibliografisk träff 2013-11-08

Long-term effects of cariprazine exposure on dopamine receptor subtypes.

Choi YK, Adham N, Kiss B, Gyertyán I, Tarazi FI.

CNS Spectr · research support, non-u.s. gov't; journal article · DOI 10.1017/s1092852913000680

Bibliografisk träff 2013-09-01

Clinical potential of cariprazine in the treatment of acute mania.

Altınbaş K, Guloksuz S, Oral ET.

Psychiatr Danub · review; journal article

Bibliografisk träff 2013-08-08

A new generation of antipsychotics: pharmacology and clinical utility of cariprazine in schizophrenia.

Caccia S, Invernizzi RW, Nobili A, Pasina L.

Ther Clin Risk Manag · review-article; journal article · DOI 10.2147/tcrm.s35137

Bibliografisk träff 2012-11-09

Cariprazine (RGH-188), a D₃-preferring dopamine D₃/D₂ receptor partial agonist antipsychotic candidate demonstrates anti-abuse potential in rats.

Román V, Gyertyán I, Sághy K, Kiss B, Szombathelyi Z.

Psychopharmacology (Berl) · journal article · DOI 10.1007/s00213-012-2906-7

Bibliografisk träff 2012-04-04

Discovery of cariprazine (RGH-188): a novel antipsychotic acting on dopamine D3/D2 receptors.

Agai-Csongor E, Domány G, Nógrádi K, Galambos J, Vágó I, Keserű GM, Greiner I, Laszlovszky I, Gere A, Schmidt E, Kiss B, Vastag M, Tihanyi K, Sághy K, Laszy J, Gyertyán I, Zájer-Balázs M, Gémesi L, Kapás M, Szombathelyi Z.

Bioorg Med Chem Lett · journal article · DOI 10.1016/j.bmcl.2012.03.104