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Publikationer i urvalet

17 träffar

Bibliografisk träff 2024-04-04

Apigenin and Rutaecarpine reduce the burden of cellular senescence in bone marrow stromal stem cells.

Ali D, Okla M, Abuelreich S, Vishnubalaji R, Ditzel N, Hamam R, Kowal JM, Sayed A, Aldahmash A, Alajez NM, Kassem M.

Front Endocrinol (Lausanne) · research-article; journal article · DOI 10.3389/fendo.2024.1360054

Bibliografisk träff 2023-12-05

Loss of MTA2-mediated downregulation of PTK7 inhibits hepatocellular carcinoma metastasis progression by modulating the FAK-MMP7 axis.

Hu HM, Lee HL, Liu CJ, Hsieh YH, Chen YS, Hsueh KC.

Environ Toxicol · journal article · DOI 10.1002/tox.24073

Bibliografisk träff 2023-12-05

Inhibition of focal adhesion kinase 2 results in a macrophage polarization shift to M2 which attenuates local and systemic inflammation and reduces heterotopic ossification after polysystem extremity trauma.

Rowe CJ, Nwaolu U, Salinas D, Hong J, Nunez J, Lansford JL, McCarthy CF, Potter BK, Levi BH, Davis TA.

Front Immunol · research support, non-u.s. gov't; research-article; journal article · DOI 10.3389/fimmu.2023.1280884

Bibliografisk träff 2023-05-24

Focal adhesion kinase activation is involved in contractile stimulation-induced detrusor muscle contraction in mice.

Maher S, Bayachou M, Fu P, Hijaz A, Liu G.

Eur J Pharmacol · research-article; journal article · DOI 10.1016/j.ejphar.2023.175807

Bibliografisk träff 2022-11-28

Coordination of LMO7 with FAK Signaling Sustains Epithelial Integrity in Renal Epithelia Exposed to Osmotic Pressure.

Zhen YY, Wu CH, Chen HC, Chang EE, Lee JJ, Chen WY, Chang JM, Tseng PY, Wang YF, Hung CC.

Cells · research-article; journal article · DOI 10.3390/cells11233805

Bibliografisk träff 2021-01-25

Structure-kinetic relationship reveals the mechanism of selectivity of FAK inhibitors over PYK2.

Berger BT, Amaral M, Kokh DB, Nunes-Alves A, Musil D, Heinrich T, Schröder M, Neil R, Wang J, Navratilova I, Bomke J, Elkins JM, Müller S, Frech M, Wade RC, Knapp S.

Cell Chem Biol · research support, non-u.s. gov't; journal article · DOI 10.1016/j.chembiol.2021.01.003

Bibliografisk träff 2019-02-19

Characterization of in vitro metabolism of focal adhesion kinase inhibitors by LC/MS/MS.

Chi Q, Wang L, Xie D, Wang X.

J Pharm Biomed Anal · journal article · DOI 10.1016/j.jpba.2019.02.028

Bibliografisk träff 2019-01-30

Inhibition of FAK Signaling Elicits Lamin A/C-Associated Nuclear Deformity and Cellular Senescence.

Chuang HH, Wang PH, Niu SW, Zhen YY, Huang MS, Hsiao M, Yang CJ.

Front Oncol · research-article; journal article · DOI 10.3389/fonc.2019.00022

Bibliografisk träff 2018-10-23

Therapeutic Potential of Focal Adhesion Kinase Inhibition in Small Cell Lung Cancer.

Aboubakar Nana F, Lecocq M, Ladjemi MZ, Detry B, Dupasquier S, Feron O, Massion PP, Sibille Y, Pilette C, Ocak S.

Mol Cancer Ther · research support, non-u.s. gov't; research-article; research support, u.s. gov't, non-p.h.s.; journal article · DOI 10.1158/1535-7163.mct-18-0328

Bibliografisk träff 2018-06-30

Attenuation of murine acute lung injury by PF-573,228, an inhibitor of focal adhesion kinase.

Lederer PA, Zhou T, Chen W, Epshtein Y, Wang H, Mathew B, Jacobson JR.

Vascul Pharmacol · research-article; journal article · DOI 10.1016/j.vph.2018.06.017

Bibliografisk träff 2018-04-06

Inhibiting focal adhesion kinase (FAK) blocks IL-4 induced VCAM-1 expression and eosinophil recruitment in vitro and in vivo.

Aulakh GK, Petri B, Wojcik KM, Colarusso P, Lee JJ, Patel KD.

J Leukoc Biol · research support, non-u.s. gov't; journal article · DOI 10.1002/jlb.3ma1117-429r

Bibliografisk träff 2018-02-22

Focal adhesion kinase a potential therapeutic target for pancreatic cancer and malignant pleural mesothelioma.

Kanteti R, Mirzapoiazova T, Riehm JJ, Dhanasingh I, Mambetsariev B, Wang J, Kulkarni P, Kaushik G, Seshacharyulu P, Ponnusamy MP, Kindler HL, Nasser MW, Batra SK, Salgia R.

Cancer Biol Ther · research-article; journal article; research support, n.i.h., extramural · DOI 10.1080/15384047.2017.1416937

Bibliografisk träff 2017-11-28

FUS-CHOP Promotes Invasion in Myxoid Liposarcoma through a SRC/FAK/RHO/ROCK-Dependent Pathway.

Tornin J, Hermida-Prado F, Padda RS, Gonzalez MV, Alvarez-Fernandez C, Rey V, Martinez-Cruzado L, Estupiñan O, Menendez ST, Fernandez-Nevado L, Astudillo A, Rodrigo JP, Lucien F, Kim Y, Leong HS, Garcia-Pedrero JM, Rodriguez R.

Neoplasia · research support, non-u.s. gov't; research-article; journal article · DOI 10.1016/j.neo.2017.11.004

Bibliografisk träff 2017-05-01

Focal adhesion kinase inhibitor PF573228 and death receptor 5 agonist lexatumumab synergistically induce apoptosis in pancreatic carcinoma.

Zhao X, Sun W, Puszyk WM, Wallet S, Hochwald S, Robertson K, Liu C.

Tumour Biol · journal article · DOI 10.1177/1010428317699120

Bibliografisk träff 2016-09-01

PF573,228 inhibits vascular tumor cell growth, migration as well as angiogenesis, induces apoptosis and abrogates PRAS40 and S6RP phosphorylation.

Mabeta P.

Acta Pharm · journal article · DOI 10.1515/acph-2016-0031

Bibliografisk träff 2011-09-08

Evidence for activation of BK Ca channels by a known inhibitor of focal adhesion kinase, PF573228.

So EC, Wu KC, Liang CH, Chen JY, Wu SN.

Life Sci · research support, non-u.s. gov't; journal article · DOI 10.1016/j.lfs.2011.08.013

Bibliografisk träff 2007-03-28

Cellular characterization of a novel focal adhesion kinase inhibitor.

Slack-Davis JK, Martin KH, Tilghman RW, Iwanicki M, Ung EJ, Autry C, Luzzio MJ, Cooper B, Kath JC, Roberts WG, Parsons JT.

J Biol Chem · journal article · DOI 10.1074/jbc.m606695200