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Publikationer i urvalet

13 träffar

Bibliografisk träff 2010-12-22

Soraphen A, an inhibitor of acetyl CoA carboxylase activity, interferes with fatty acid elongation.

Jump DB, Torres-Gonzalez M, Olson LK.

Biochem Pharmacol · research support, non-u.s. gov't; research-article; journal article; research support, n.i.h., extramural · DOI 10.1016/j.bcp.2010.12.014

Bibliografisk träff 2009-01-01

Asymmetric total synthesis of soraphen A: a flexible alkyne strategy.

Trost BM, Sieber JD, Qian W, Dhawan R, Ball ZT.

Angew Chem Int Ed Engl · research support, non-u.s. gov't; research-article; journal article; research support, n.i.h., extramural · DOI 10.1002/anie.200901907

Bibliografisk träff 2006-11-01

On the biosynthetic origin of methoxymalonyl-acyl carrier protein, the substrate for incorporation of "glycolate" units into ansamitocin and soraphen A.

Wenzel SC, Williamson RM, Grünanger C, Xu J, Gerth K, Martinez RA, Moss SJ, Carroll BJ, Grond S, Unkefer CJ, Müller R, Floss HG.

J Am Chem Soc · research support, non-u.s. gov't; journal article; research support, n.i.h., extramural · DOI 10.1021/ja064408t

Bibliografisk träff 2006-06-01

Studies toward soraphen A: an aldol-metathesis avenue to the macrocyclic framework.

Vincent G, Mansfield DJ, Vors JP, Ciufolini MA.

Org Lett · research support, non-u.s. gov't; journal article · DOI 10.1021/ol060882s

Bibliografisk träff 2004-12-01

A mechanism for the potent inhibition of eukaryotic acetyl-coenzyme A carboxylase by soraphen A, a macrocyclic polyketide natural product.

Shen Y, Volrath SL, Weatherly SC, Elich TD, Tong L.

Mol Cell · research support, u.s. gov't, p.h.s.; journal article · DOI 10.1016/j.molcel.2004.11.034

Bibliografisk träff 2004-08-01

Heterologous production of the antifungal polyketide antibiotic soraphen A of Sorangium cellulosum So ce26 in Streptomyces lividans.

Zirkle R, Ligon JM, Molnár I.

Microbiology (Reading) · journal article · DOI 10.1099/mic.0.27138-0

Bibliografisk träff 2004-04-01

A new dominant selection marker for transformation of Pichia pastoris to soraphen A resistance.

Wan H, Sjölinder M, Schairer HU, Leclerque A.

J Microbiol Methods · research support, non-u.s. gov't; journal article · DOI 10.1016/j.mimet.2003.11.013

Bibliografisk träff 2004-01-01

Cloning, sequence analysis and disruption of the mglA gene involved in swarming motility of Sorangium cellulosum So ce26, a producer of the antifungal polyketide antibiotic soraphen A.

Zirkle R, Ligon JM, Molnár I.

J Biosci Bioeng · journal article · DOI 10.1016/s1389-1723(04)70202-9

Bibliografisk träff 2003-06-01

Investigation of the early stages in soraphen A biosynthesis.

Hill AM, Thompson BL, Harris JP, Segret R.

Chem Commun (Camb) · research support, non-u.s. gov't; journal article · DOI 10.1039/b303542p

Bibliografisk träff 2002-02-01

Characterization of the biosynthetic gene cluster for the antifungal polyketide soraphen A from Sorangium cellulosum So ce26.

Ligon J, Hill S, Beck J, Zirkle R, Molnár I, Zawodny J, Money S, Schupp T.

Gene · journal article · DOI 10.1016/s0378-1119(02)00396-7

Bibliografisk träff 1998-12-01

Isolation and characterisation of the acetyl-CoA carboxylase gene from Aspergillus nidulans.

Morrice J, MacKenzie DA, Parr AJ, Archer DB.

Curr Genet · research support, non-u.s. gov't; journal article · DOI 10.1007/s002940050410

Bibliografisk träff 1995-07-01

A Sorangium cellulosum (myxobacterium) gene cluster for the biosynthesis of the macrolide antibiotic soraphen A: cloning, characterization, and homology to polyketide synthase genes from actinomycetes.

Schupp T, Toupet C, Cluzel B, Neff S, Hill S, Beck JJ, Ligon JM.

J Bacteriol · research-article; journal article · DOI 10.1128/jb.177.13.3673-3679.1995

Bibliografisk träff 1994-02-01

Identification of the yeast ACC1 gene product (acetyl-CoA carboxylase) as the target of the polyketide fungicide soraphen A.

Vahlensieck HF, Pridzun L, Reichenbach H, Hinnen A.

Curr Genet · journal article · DOI 10.1007/bf00309532