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Publikationer i urvalet

26 träffar

Bibliografisk träff 2024-06-18

Endocannabinoid Receptor 2 Function is Associated with Tumor-Associated Macrophage Accumulation and Increases in T Cell Number to Initiate a Potent Antitumor Response in a Syngeneic Murine Model of Glioblastoma.

Duan J, Chen J, Lin Y, Lin SL, Wu J.

Cannabis Cannabinoid Res · research support, non-u.s. gov't; research-article; journal article · DOI 10.1089/can.2024.0063

Bibliografisk träff 2023-10-22

β-Caryophyllene Inhibits Oxaliplatin-Induced Peripheral Neuropathy in Mice: Role of Cannabinoid Type 2 Receptors, Oxidative Stress and Neuroinflammation.

Agnes JP, Dos Santos B, das Neves RN, Luciano VMM, Benvenutti L, Goldoni FC, Schran RG, Santin JR, Quintão NLM, Zanotto-Filho A.

Antioxidants (Basel) · research-article; journal article · DOI 10.3390/antiox12101893

Bibliografisk träff 2023-10-03

Evaluation of [18F]RoSMA-18-d6 as a CB2 PET Radioligand in Nonhuman Primates.

Haider A, Haider A, Wang L, Gobbi L, Li Y, Chaudhary A, Zhou X, Chen J, Zhao C, Rong J, Xiao Z, Hou L, Elghazawy NH, Sippl W, Davenport AT, Daunais JB, Ahmed H, Crowe R, Honer M, Rominger A, Grether U, Liang SH, Ametamey SM.

ACS Chem Neurosci · research support, non-u.s. gov't; journal article · DOI 10.1021/acschemneuro.3c00222

Bibliografisk träff 2023-01-25

CB2R agonist GW405833 alleviates acute liver failure in mice via inhibiting HIF-1α-mediated reprogramming of glycometabolism and macrophage proliferation.

Cai SL, Fan XG, Wu J, Wang Y, Hu XW, Pei SY, Zheng YX, Chen J, Huang Y, Li N, Huang ZB.

Acta Pharmacol Sin · research-article; journal article · DOI 10.1038/s41401-022-01037-8

Bibliografisk träff 2022-05-05

Activation of cannabinoid receptors in breast cancer cells improves osteoblast viability in cancer-bone interaction model while reducing breast cancer cell survival and migration.

Khunluck T, Lertsuwan K, Chutoe C, Sooksawanwit S, Inson I, Teerapornpuntakit J, Tohtong R, Charoenphandhu N.

Sci Rep · research support, non-u.s. gov't; research-article; journal article · DOI 10.1038/s41598-022-11116-9

Bibliografisk träff 2022-04-01

A CB2 Receptor Agonist Reduces the Production of Inflammatory Mediators and Improves Locomotor Activity in Experimental Autoimmune Encephalomyelitis.

Parastouei K, Aarabi MH, Hamidi GA, Nasehi Z, Kabiri-Arani S, Jozi F, Shahaboddin ME.

Rep Biochem Mol Biol · research-article; journal article · DOI 10.52547/rbmb.11.1.1

Bibliografisk träff 2021-09-01

Protective effect of cannabinoids on gastric mucosal lesions induced by water immersion restrain stress in rats.

Elgohary R, Abdelsalam RM, Abdel-Salam OM, Khattab MM, Salem NA, El-Khyat ZA, Morsy FA.

Iran J Basic Med Sci · research-article; journal article · DOI 10.22038/ijbms.2021.54338.12213

Bibliografisk träff 2020-01-07

Design and synthesis of fluorescent ligands for the detection of cannabinoid type 2 receptor (CB2R).

Spinelli F, Giampietro R, Stefanachi A, Riganti C, Kopecka J, Abatematteo FS, Leonetti F, Colabufo NA, Mangiatordi GF, Nicolotti O, Perrone MG, Brea J, Loza MI, Infantino V, Abate C, Contino M.

Eur J Med Chem · journal article · DOI 10.1016/j.ejmech.2020.112037

Bibliografisk träff 2019-12-02

Cannabinoid receptor 2 promotes the intracellular degradation of HMGB1 via the autophagy-lysosome pathway in macrophage.

Zhou H, Du R, Li G, Bai Z, Ma J, Mao C, Wang J, Gui H.

Int Immunopharmacol · journal article · DOI 10.1016/j.intimp.2019.106007

Bibliografisk träff 2019-09-17

Indole compounds with N-ethyl morpholine moieties as CB2 receptor agonists for anti-inflammatory management of pain: synthesis and biological evaluation.

Li J, Ji J, Xu R, Li Z.

Medchemcomm · research-article; journal article · DOI 10.1039/c9md00173e

Bibliografisk träff 2019-03-27

Protective effects of specific cannabinoid receptor 2 agonist GW405833 on concanavalin A-induced acute liver injury in mice.

Huang ZB, Zheng YX, Li N, Cai SL, Huang Y, Wang J, Hu XW, Wang Y, Wu J, Fan XG.

Acta Pharmacol Sin · research-article; journal article · DOI 10.1038/s41401-019-0213-0

Bibliografisk träff 2018-11-01

Modulation of gastric acid secretion by cannabinoids in rats.

Salama RAA, Abdelsalam RM, Abdel-Salam OME, Khattab MM, Salem NA, El-Khyat ZA, Morsy FA, Eldenshary EDS.

J Biochem Mol Toxicol · journal article · DOI 10.1002/jbt.22256

Bibliografisk träff 2018-09-18

The exogenous administration of CB2 specific agonist, GW405833, inhibits inflammation by reducing cytokine production and oxidative stress.

Parlar A, Arslan SO, Doğan MF, Çam SA, Yalçin A, Elibol E, Özer MK, Üçkardeş F, Kara H.

Exp Ther Med · research-article; journal article · DOI 10.3892/etm.2018.6753

Bibliografisk träff 2017-06-07

Cannabinoid CB2 Agonist GW405833 Suppresses Inflammatory and Neuropathic Pain through a CB1 Mechanism that is Independent of CB2 Receptors in Mice.

Li AL, Carey LM, Mackie K, Hohmann AG.

J Pharmacol Exp Ther · research support, non-u.s. gov't; research-article; journal article; research support, n.i.h., extramural · DOI 10.1124/jpet.117.241901

Bibliografisk träff 2016-12-07

Two Janus Cannabinoids That Are Both CB2 Agonists and CB1 Antagonists.

Dhopeshwarkar A, Murataeva N, Makriyannis A, Straiker A, Mackie K.

J Pharmacol Exp Ther · research-article; journal article · DOI 10.1124/jpet.116.236539

Bibliografisk träff 2016-07-19

Cannabinoid receptor subtype 2 (CB2R) agonist, GW405833 reduces agonist-induced Ca(2+) oscillations in mouse pancreatic acinar cells.

Huang Z, Wang H, Wang J, Zhao M, Sun N, Sun F, Shen J, Zhang H, Xia K, Chen D, Gao M, Hammer RP, Liu Q, Xi Z, Fan X, Wu J.

Sci Rep · research support, non-u.s. gov't; research-article; journal article · DOI 10.1038/srep29757

Bibliografisk träff 2016-01-05

Effect of cannabinoids on CGRP release in the isolated rat lumbar spinal cord.

Milne M, Ashton JC.

Neurosci Lett · research support, non-u.s. gov't; journal article · DOI 10.1016/j.neulet.2015.12.060

Bibliografisk träff 2014-04-12

The cannabinoid CB2 receptor agonist GW405833 does not ameliorate brain damage induced by hypoxia-ischemia in rats.

Rivers-Auty JR, Smith PF, Ashton JC.

Neurosci Lett · journal article · DOI 10.1016/j.neulet.2014.03.077

Bibliografisk träff 2013-05-28

Cannabinoid receptor 2 protects against acute experimental sepsis in mice.

Gui H, Sun Y, Luo ZM, Su DF, Dai SM, Liu X.

Mediators Inflamm · research support, non-u.s. gov't; research-article; journal article · DOI 10.1155/2013/741303

Bibliografisk träff 2011-06-16

Synthesis, in vitro and in vivo evaluation of fluorine-18 labelled FE-GW405833 as a PET tracer for type 2 cannabinoid receptor imaging.

Evens N, Vandeputte C, Muccioli GG, Lambert DM, Baekelandt V, Verbruggen AM, Debyser Z, Van Laere K, Bormans GM.

Bioorg Med Chem · research support, non-u.s. gov't; evaluation study; journal article · DOI 10.1016/j.bmc.2011.06.033

Bibliografisk träff 2010-09-21

Paradoxical effects of the cannabinoid CB2 receptor agonist GW405833 on rat osteoarthritic knee joint pain.

Schuelert N, Zhang C, Mogg AJ, Broad LM, Hepburn DL, Nisenbaum ES, Johnson MP, McDougall JJ.

Osteoarthritis Cartilage · research support, non-u.s. gov't; journal article · DOI 10.1016/j.joca.2010.09.005

Bibliografisk träff 2009-06-22

Constitutive activity of cannabinoid-2 (CB2) receptors plays an essential role in the protean agonism of (+)AM1241 and L768242.

Mancini I, Brusa R, Quadrato G, Foglia C, Scandroglio P, Silverman LS, Tulshian D, Reggiani A, Beltramo M.

Br J Pharmacol · comparative study; research support, non-u.s. gov't; research-article; journal article · DOI 10.1111/j.1476-5381.2009.00154.x

Bibliografisk träff 2009-04-03

Depression-like behaviour in rats with mononeuropathy is reduced by the CB2-selective agonist GW405833.

Hu B, Doods H, Treede RD, Ceci A.

Pain · journal article · DOI 10.1016/j.pain.2009.02.018

Bibliografisk träff 2005-11-28

A role for cannabinoid receptors, but not endogenous opioids, in the antinociceptive activity of the CB2-selective agonist, GW405833.

Whiteside GT, Gottshall SL, Boulet JM, Chaffer SM, Harrison JE, Pearson MS, Turchin PI, Mark L, Garrison AE, Valenzano KJ.

Eur J Pharmacol · journal article · DOI 10.1016/j.ejphar.2005.10.043

Bibliografisk träff 2005-04-01

Pharmacological and pharmacokinetic characterization of the cannabinoid receptor 2 agonist, GW405833, utilizing rodent models of acute and chronic pain, anxiety, ataxia and catalepsy.

Valenzano KJ, Tafesse L, Lee G, Harrison JE, Boulet JM, Gottshall SL, Mark L, Pearson MS, Miller W, Shan S, Rabadi L, Rotshteyn Y, Chaffer SM, Turchin PI, Elsemore DA, Toth M, Koetzner L, Whiteside GT.

Neuropharmacology · comparative study; journal article · DOI 10.1016/j.neuropharm.2004.12.008

Bibliografisk träff 2002-04-01

CB1 and CB2 cannabinoid receptors are implicated in inflammatory pain.

Clayton N, Marshall FH, Bountra C, O'Shaughnessy CT.

Pain · journal article · DOI 10.1016/s0304-3959(01)00454-7

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Publikationer i urvalet

Endocannabinoid Receptor 2 Function is Associated with Tumor-Associated Macrophage Accumulation and Increases in T Cell Number to Initiate a Potent Antitumor Response in a Syngeneic Murine Model of Glioblastoma.

β-Caryophyllene Inhibits Oxaliplatin-Induced Peripheral Neuropathy in Mice: Role of Cannabinoid Type 2 Receptors, Oxidative Stress and Neuroinflammation.

Evaluation of [<sup>18</sup>F]RoSMA-18-d<sub>6</sub> as a CB2 PET Radioligand in Nonhuman Primates.

CB2R agonist GW405833 alleviates acute liver failure in mice via inhibiting HIF-1α-mediated reprogramming of glycometabolism and macrophage proliferation.

Activation of cannabinoid receptors in breast cancer cells improves osteoblast viability in cancer-bone interaction model while reducing breast cancer cell survival and migration.

A CB2 Receptor Agonist Reduces the Production of Inflammatory Mediators and Improves Locomotor Activity in Experimental Autoimmune Encephalomyelitis.

Protective effect of cannabinoids on gastric mucosal lesions induced by water immersion restrain stress in rats.

Design and synthesis of fluorescent ligands for the detection of cannabinoid type 2 receptor (CB2R).

Cannabinoid receptor 2 promotes the intracellular degradation of HMGB1 via the autophagy-lysosome pathway in macrophage.

Indole compounds with <i>N</i>-ethyl morpholine moieties as CB2 receptor agonists for anti-inflammatory management of pain: synthesis and biological evaluation.

Protective effects of specific cannabinoid receptor 2 agonist GW405833 on concanavalin A-induced acute liver injury in mice.

Modulation of gastric acid secretion by cannabinoids in rats.

The exogenous administration of CB2 specific agonist, GW405833, inhibits inflammation by reducing cytokine production and oxidative stress.

Cannabinoid CB<sub>2</sub> Agonist GW405833 Suppresses Inflammatory and Neuropathic Pain through a CB<sub>1</sub> Mechanism that is Independent of CB<sub>2</sub> Receptors in Mice.

Two Janus Cannabinoids That Are Both CB2 Agonists and CB1 Antagonists.

Cannabinoid receptor subtype 2 (CB2R) agonist, GW405833 reduces agonist-induced Ca(2+) oscillations in mouse pancreatic acinar cells.

Effect of cannabinoids on CGRP release in the isolated rat lumbar spinal cord.

The cannabinoid CB2 receptor agonist GW405833 does not ameliorate brain damage induced by hypoxia-ischemia in rats.

Cannabinoid receptor 2 protects against acute experimental sepsis in mice.

Synthesis, in vitro and in vivo evaluation of fluorine-18 labelled FE-GW405833 as a PET tracer for type 2 cannabinoid receptor imaging.

Paradoxical effects of the cannabinoid CB2 receptor agonist GW405833 on rat osteoarthritic knee joint pain.

Constitutive activity of cannabinoid-2 (CB2) receptors plays an essential role in the protean agonism of (+)AM1241 and L768242.

Depression-like behaviour in rats with mononeuropathy is reduced by the CB2-selective agonist GW405833.

A role for cannabinoid receptors, but not endogenous opioids, in the antinociceptive activity of the CB2-selective agonist, GW405833.

Pharmacological and pharmacokinetic characterization of the cannabinoid receptor 2 agonist, GW405833, utilizing rodent models of acute and chronic pain, anxiety, ataxia and catalepsy.

CB1 and CB2 cannabinoid receptors are implicated in inflammatory pain.