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Publikationer i urvalet

50 träffar

Bibliografisk träff 2021-04-26

A naphthalimide-polyamine conjugate preferentially accumulates in hepatic carcinoma metastases as a lysosome-targeted antimetastatic agent.

Ma J, Li L, Yue K, Zhang Z, Su S, Chen Y, Yu L, Zhang P, Ma R, Li Y, Ma Y, Jia H, Wang C, Wang J, Xie S.

Eur J Med Chem · journal article · DOI 10.1016/j.ejmech.2021.113469

Bibliografisk träff 2020-10-17

Design, synthesis and antitumor evaluation of new 1,8-naphthalimide derivatives targeting nuclear DNA.

Liang GB, Wei JH, Jiang H, Huang RZ, Qin JT, Wang HL, Wang HS, Zhang Y.

Eur J Med Chem · journal article · DOI 10.1016/j.ejmech.2020.112951

Bibliografisk träff 2019-12-23

A review of currently identified small molecule modulators of microRNA function.

Van Meter EN, Onyango JA, Teske KA.

Eur J Med Chem · review; journal article · DOI 10.1016/j.ejmech.2019.112008

Bibliografisk träff 2018-11-08

Design and synthesis of DNA-intercalative naphthalimide-benzothiazole/cinnamide derivatives: cytotoxicity evaluation and topoisomerase-IIα inhibition.

Sankara Rao N, Nagesh N, Lakshma Nayak V, Sunkari S, Tokala R, Kiranmai G, Regur P, Shankaraiah N, Kamal A, Kamal A.

Medchemcomm · research-article; journal article · DOI 10.1039/c8md00395e

Bibliografisk träff 2018-09-24

l,8-Naphthalimide based DNA intercalators and anticancer agents. A systematic review from 2007 to 2017.

Tomczyk MD, Walczak KZ.

Eur J Med Chem · systematic review; journal article · DOI 10.1016/j.ejmech.2018.09.055

Bibliografisk träff 2018-07-23

Discovery of the Polyamine Conjugate with Benzo[ cd]indol-2(1 H)-one as a Lysosome-Targeted Antimetastatic Agent.

Li J, Tian R, Ge C, Chen Y, Liu X, Wang Y, Yang Y, Luo W, Dai F, Wang S, Chen S, Xie S, Wang C.

J Med Chem · journal article · DOI 10.1021/acs.jmedchem.8b00694

Bibliografisk träff 2018-07-06

Synthesis and biological evaluation of novel asymmetric naphthalene diimide derivatives as anticancer agents depending on ROS generation.

Xu X, Wang S, Chang Y, Ge C, Li X, Feng Y, Xie S, Wang C, Dai F, Luo W.

Medchemcomm · research-article; journal article · DOI 10.1039/c8md00265g

Bibliografisk träff 2018-01-09

Lysosomes-targeting imaging and anticancer properties of novel bis-naphthalimide derivatives.

Rong RX, Wang SS, Liu X, Li RF, Wang KR, Cao ZR, Li XL.

Bioorg Med Chem Lett · research support, non-u.s. gov't; journal article · DOI 10.1016/j.bmcl.2018.01.008

Bibliografisk träff 2017-11-11

Synthesis and biological evaluation of novel alkylated polyamine analogues as potential anticancer agents.

Li M, Wang Y, Ge C, Chang L, Wang C, Tian Z, Wang S, Dai F, Zhao L, Xie S.

Eur J Med Chem · journal article · DOI 10.1016/j.ejmech.2017.10.069

Bibliografisk träff 2017-06-29

Discovery of potent molecular chimera (CM358) to treat human metastatic melanoma.

Gilad Y, Tuchinsky H, Ben-David G, Minnes R, Gancz A, Senderowitz H, Luboshits G, Firer MA, Gellerman G.

Eur J Med Chem · journal article · DOI 10.1016/j.ejmech.2017.06.066

Bibliografisk träff 2017-02-21

Design, Synthesis, and Biological Evaluation of Mitochondria-Targeted Flavone-Naphthalimide-Polyamine Conjugates with Antimetastatic Activity.

Dai F, Li Q, Wang Y, Ge C, Feng C, Xie S, He H, Xu X, Wang C.

J Med Chem · research support, non-u.s. gov't; journal article · DOI 10.1021/acs.jmedchem.6b01846

Bibliografisk träff 2017-02-13

5-Ethynylarylnaphthalimides as antitumor agents: Synthesis and biological evaluation.

Quintana-Espinoza P, Martín-Acosta P, Amesty Á, Martín-Rodríguez P, Lorenzo-Castrillejo I, Fernández-Pérez L, Machín F, Estévez-Braun A.

Bioorg Med Chem · journal article · DOI 10.1016/j.bmc.2017.02.024

Bibliografisk träff 2016-11-30

Synthesis of novel C4-benzazole naphthalimide derivatives with potent anti-tumor properties against murine melanoma.

Lu YT, Chen TL, Chang KS, Chang CM, Wei TY, Liu JW, Hsiao CA, Shih TL.

Bioorg Med Chem · research support, non-u.s. gov't; journal article · DOI 10.1016/j.bmc.2016.11.057

Bibliografisk träff 2015-07-15

Antiproliferative and apoptosis-inducing activities of novel naphthalimide-cyclam conjugates through dual topoisomerase (topo) I/II inhibition.

Tan S, Sun D, Lyu J, Sun X, Wu F, Li Q, Yang Y, Liu J, Wang X, Chen Z, Li H, Qian X, Xu Y.

Bioorg Med Chem · research support, non-u.s. gov't; journal article · DOI 10.1016/j.bmc.2015.07.011

Bibliografisk träff 2015-04-17

Effect of intercalator substituent and nucleotide sequence on the stability of DNA- and RNA-naphthalimide complexes.

Johnson CA, Hudson GA, Hardebeck LK, Jolley EA, Ren Y, Lewis M, Znosko BM.

Bioorg Med Chem · research support, non-u.s. gov't; research support, u.s. gov't, non-p.h.s.; journal article · DOI 10.1016/j.bmc.2015.04.030

Bibliografisk träff 2014-05-05

Synthesis, cytotoxicity, DNA binding and topoisomerase II inhibition of cassiarin A derivatives.

Luesakul U, Palaga T, Krusong K, Ngamrojanavanich N, Vilaivan T, Puthong S, Muangsin N.

Bioorg Med Chem Lett · research support, non-u.s. gov't; journal article · DOI 10.1016/j.bmcl.2014.04.107

Bibliografisk träff 2013-12-14

Synthesis, anticancer activity and DNA-binding properties of novel 4-pyrazolyl-1,8-naphthalimide derivatives.

Li S, Xu S, Tang Y, Ding S, Zhang J, Wang S, Zhou G, Zhou C, Li X.

Bioorg Med Chem Lett · research support, non-u.s. gov't; journal article · DOI 10.1016/j.bmcl.2013.12.014

Bibliografisk träff 2013-08-29

Synthesis and study of antiproliferative, antitopoisomerase II, DNA-intercalating and DNA-damaging activities of arylnaphthalimides.

Quintana-Espinoza P, García-Luis J, Amesty A, Martín-Rodríguez P, Lorenzo-Castrillejo I, Ravelo AG, Fernández-Pérez L, Machín F, Estévez-Braun A.

Bioorg Med Chem · research support, non-u.s. gov't; journal article · DOI 10.1016/j.bmc.2013.08.039

Bibliografisk träff 2013-08-11

Synthesis, in vitro evaluation and molecular modelling of naphthalimide analogue as anticancer agents.

Verma M, Luxami V, Paul K.

Eur J Med Chem · research support, non-u.s. gov't; journal article · DOI 10.1016/j.ejmech.2013.07.027

Bibliografisk träff 2013-05-14

Naphthalimides exhibit in vitro antiproliferative and antiangiogenic activities by inhibiting both topoisomerase II (topo II) and receptor tyrosine kinases (RTKs).

Wang X, Chen Z, Tong L, Tan S, Zhou W, Peng T, Han K, Ding J, Xie H, Xu Y.

Eur J Med Chem · research support, non-u.s. gov't; journal article · DOI 10.1016/j.ejmech.2013.05.002

Bibliografisk träff 2013-01-03

Oxo-heterocyclic fused naphthalimides as antitumor agents: synthesis and biological evaluation.

Tan S, Yin H, Chen Z, Qian X, Xu Y.

Eur J Med Chem · research support, non-u.s. gov't; journal article · DOI 10.1016/j.ejmech.2012.12.039

Bibliografisk träff 2012-03-28

Nonhematotoxic naphthalene diimide modified by polyamine: synthesis and biological evaluation.

Wang Y, Zhang X, Zhao J, Xie S, Wang C.

J Med Chem · research support, non-u.s. gov't; journal article · DOI 10.1021/jm300168w

Bibliografisk träff 2012-03-01

Selenium-containing naphthalimides as anticancer agents: design, synthesis and bioactivity.

Zhao L, Li J, Li Y, Liu J, Wirth T, Li Z.

Bioorg Med Chem · research support, non-u.s. gov't; journal article · DOI 10.1016/j.bmc.2012.02.049

Bibliografisk träff 2011-11-20

Unprecedented synthesis, in vitro and in vivo anti-cancer evaluation of novel triazolonaphthalimide derivatives.

Li S, Zhong W, Li Z, Meng X.

Eur J Med Chem · research support, non-u.s. gov't; journal article · DOI 10.1016/j.ejmech.2011.11.025

Bibliografisk träff 2011-10-04

Design, synthesis and biological evaluation of substituted 11H-benzo[a]carbazole-5-carboxamides as novel antitumor agents.

Wang YQ, Li XH, He Q, Chen Y, Xie YY, Ding J, Miao ZH, Yang CH.

Eur J Med Chem · research support, non-u.s. gov't; journal article · DOI 10.1016/j.ejmech.2011.09.050

Bibliografisk träff 2011-03-12

Small molecule inhibitor of the RPA70 N-terminal protein interaction domain discovered using in silico and in vitro methods.

Glanzer JG, Liu S, Oakley GG.

Bioorg Med Chem · research support, non-u.s. gov't; research-article; journal article; research support, n.i.h., extramural · DOI 10.1016/j.bmc.2011.03.012

Bibliografisk träff 2011-02-03

The novel anti-tumor agents of 4-triazol-1,8-naphthalimides: synthesis, cytotoxicity, DNA intercalation and photocleavage.

Li X, Lin Y, Wang Q, Yuan Y, Zhang H, Qian X.

Eur J Med Chem · research support, non-u.s. gov't; journal article · DOI 10.1016/j.ejmech.2011.01.050

Bibliografisk träff 2010-11-30

5-Non-amino aromatic substituted naphthalimides as potential antitumor agents: Synthesis via Suzuki reaction, antiproliferative activity, and DNA-binding behavior.

Xie L, Cui J, Qian X, Xu Y, Liu J, Xu R.

Bioorg Med Chem · research support, non-u.s. gov't; journal article · DOI 10.1016/j.bmc.2010.11.055

Bibliografisk träff 2010-03-01

A new class of naphthalimide-based antitumor agents that inhibit topoisomerase II and induce lysosomal membrane permeabilization and apoptosis.

Chen Z, Liang X, Zhang H, Xie H, Liu J, Xu Y, Zhu W, Wang Y, Wang X, Tan S, Kuang D, Qian X.

J Med Chem · research support, non-u.s. gov't; journal article · DOI 10.1021/jm100025u

Bibliografisk träff 2009-07-16

Novel naphthalimide derivatives as potential apoptosis-inducing agents: design, synthesis and biological evaluation.

Wu A, Xu Y, Qian X, Wang J, Liu J.

Eur J Med Chem · research support, non-u.s. gov't; journal article · DOI 10.1016/j.ejmech.2009.07.011