JWH133 inhibits MPP<sup>+</sup>-induced inflammatory response and iron influx in astrocytes.
Jia Y, Deng H, Qin Q, Ma Z.
Neurosci Lett · research support, non-u.s. gov't; journal article · DOI 10.1016/j.neulet.2020.134779 PUBLICATION REGISTRY
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37 hitsReduced cannabinoid 2 receptor activity increases susceptibility to induced seizures in mice.
Shapiro L, Wong JC, Escayg A.
Epilepsia · research support, non-u.s. gov't; research-article; journal article; research support, n.i.h., extramural · DOI 10.1111/epi.16388The ameliorating effect of cannabinoid type 2 receptor activation on brain, lung, liver and heart damage in cecal ligation and puncture-induced sepsis model in rats.
Çakır M, Tekin S, Okan A, Çakan P, Doğanyiğit Z.
Int Immunopharmacol · journal article · DOI 10.1016/j.intimp.2019.105978Paternal activation of CB<sub>2</sub> cannabinoid receptor impairs placental and embryonic growth via an epigenetic mechanism.
Innocenzi E, De Domenico E, Ciccarone F, Zampieri M, Rossi G, Cicconi R, Bernardini R, Mattei M, Grimaldi P.
Sci Rep · research support, non-u.s. gov't; research-article; journal article · DOI 10.1038/s41598-019-53579-3Cannabinoid receptor 2 activation decreases severity of cyclophosphamide-induced cystitis via regulating autophagy.
Liu Q, Wu Z, Liu Y, Chen L, Zhao H, Guo H, Zhu K, Wang W, Chen S, Zhou N, Li Y, Shi B.
Neurourol Urodyn · research support, non-u.s. gov't; journal article · DOI 10.1002/nau.24205The protective effect of cannabinoid type 2 receptor activation on renal ischemia-reperfusion injury.
Çakır M, Tekin S, Doğanyiğit Z, Çakan P, Kaymak E.
Mol Cell Biochem · journal article · DOI 10.1007/s11010-019-03616-6Selective Activation of Cannabinoid Receptor 2 Attenuates Myocardial Infarction via Suppressing NLRP3 Inflammasome.
Yu W, Jin G, Zhang J, Wei W.
Inflammation · journal article · DOI 10.1007/s10753-018-0945-xHypothalamic endocannabinoid signalling modulates aversive responses related to panic attacks.
Viana TG, Bastos JR, Costa RB, Hott SC, Mansur FS, Coimbra CC, Resstel LB, Aguiar DC, Moreira FA.
Neuropharmacology · research support, non-u.s. gov't; journal article · DOI 10.1016/j.neuropharm.2019.01.022Behavioral effects of psychostimulants in mutant mice with cell-type specific deletion of CB2 cannabinoid receptors in dopamine neurons.
Canseco-Alba A, Schanz N, Sanabria B, Zhao J, Lin Z, Liu QR, Onaivi ES.
Behav Brain Res · research support, n.i.h., intramural; research support, non-u.s. gov't; research-article; journal article; research support, n.i.h., extramural · DOI 10.1016/j.bbr.2018.11.043Cannabinoid type 2 receptor agonist JWH-133, attenuates Okadaic acid induced spatial memory impairment and neurodegeneration in rats.
Çakır M, Tekin S, Doğanyiğit Z, Erden Y, Soytürk M, Çiğremiş Y, Sandal S.
Life Sci · journal article · DOI 10.1016/j.lfs.2018.11.058Bortezomib and endocannabinoid/endovanilloid system: a synergism in osteosarcoma.
Punzo F, Tortora C, Di Pinto D, Pota E, Argenziano M, Di Paola A, Casale F, Rossi F.
Pharmacol Res · journal article · DOI 10.1016/j.phrs.2018.09.017CB2R agonist prevents nicotine induced lung fibrosis.
Wawryk-Gawda E, Chłapek K, Zarobkiewicz MK, Lis-Sochocka M, Chylińska-Wrzos P, Boguszewska-Czubara A, Sławiński MA, Franczak A, Jodłowska-Jędrych B, Biała G.
Exp Lung Res · journal article · DOI 10.1080/01902148.2018.1543368Cannabinoid receptor 2 agonist attenuates blood‑brain barrier damage in a rat model of intracerebral hemorrhage by activating the Rac1 pathway.
Wang Z, Li Y, Cai S, Li R, Cao G.
Int J Mol Med · journal article · DOI 10.3892/ijmm.2018.3834Pharmacological regulation of cannabinoid CB2 receptor modulates the reinforcing and motivational actions of ethanol.
Navarrete F, García-Gutiérrez MS, Manzanares J.
Biochem Pharmacol · research support, non-u.s. gov't; journal article · DOI 10.1016/j.bcp.2018.07.041A cannabinoid receptor 2 agonist reduces blood-brain barrier damage via induction of MKP-1 after intracerebral hemorrhage in rats.
Li L, Yun D, Zhang Y, Tao Y, Tan Q, Qiao F, Luo B, Liu Y, Fan R, Xian J, Yu A.
Brain Res · research support, non-u.s. gov't; journal article · DOI 10.1016/j.brainres.2018.06.006Involvement of the CB<sub>2</sub> cannabinoid receptor in cell growth inhibition and G0/G1 cell cycle arrest via the cannabinoid agonist WIN 55,212-2 in renal cell carcinoma.
Khan MI, Sobocińska AA, Brodaczewska KK, Zielniok K, Gajewska M, Kieda C, Czarnecka AM, Szczylik C.
BMC Cancer · research-article; journal article · DOI 10.1186/s12885-018-4496-1Activation of cannabinoid receptor type 2 by JWH133 alleviates bleomycin-induced pulmonary fibrosis in mice.
Fu Q, Zheng Y, Dong X, Wang L, Jiang CG.
Oncotarget · research-article; journal article · DOI 10.18632/oncotarget.21975Corrigendum to "A selective CB2R agonist (JWH133) restores neuronal circuit after Germinal Matrix Hemorrhage in the preterm via CX3CR1<sup>+</sup> microglia" [Neuropharm. 119 (2017) 157-169].
Tang J, Miao H, Jiang B, Chen Q, Tan L, Tao Y, Zhang J, Gao F, Feng H, Zhu G, Chen Z.
Neuropharmacology · journal article · DOI 10.1016/j.neuropharm.2017.06.033ACPA and JWH-133 modulate the vascular tone of superior mesenteric arteries through cannabinoid receptors, BK<sub>Ca</sub> channels, and nitric oxide dependent mechanisms.
López-Dyck E, Andrade-Urzúa F, Elizalde A, Ferrer-Villada T, Dagnino-Acosta A, Huerta M, Osuna-Calleros Z, Rangel-Sandoval C, Sánchez-Pastor E.
Pharmacol Rep · journal article · DOI 10.1016/j.pharep.2017.06.011Attenuation of Cocaine-Induced Conditioned Place Preference and Motor Activity via Cannabinoid CB2 Receptor Agonism and CB1 Receptor Antagonism in Rats.
Delis F, Polissidis A, Poulia N, Justinova Z, Nomikos GG, Goldberg SR, Antoniou K.
Int J Neuropsychopharmacol · research-article; journal article · DOI 10.1093/ijnp/pyw102A selective CB2R agonist (JWH133) restores neuronal circuit after Germinal Matrix Hemorrhage in the preterm via CX3CR1<sup>+</sup> microglia.
Tang J, Miao H, Jiang B, Chen Q, Tan L, Tao Y, Zhang J, Gao F, Feng H, Zhu G, Chen Z.
Neuropharmacology · journal article · DOI 10.1016/j.neuropharm.2017.01.027Cannabinoid Type-2 Receptor Drives Neurogenesis and Improves Functional Outcome After Stroke.
Bravo-Ferrer I, Cuartero MI, Zarruk JG, Pradillo JM, Hurtado O, Romera VG, Díaz-Alonso J, García-Segura JM, Guzmán M, Lizasoain I, Galve-Roperh I, Moro MA.
Stroke · journal article · DOI 10.1161/strokeaha.116.014793The Effect of Muscarinic Receptor Modulators on the Antinociception Induced by CB2 Receptor Agonist, JWH133 in Mice.
Alipour M, Fekrmandi F, Onsori S, Tabrizian P, Jafari MR.
Drug Res (Stuttg) · journal article · DOI 10.1055/s-0042-112365Functional Selectivity of CB2 Cannabinoid Receptor Ligands at a Canonical and Noncanonical Pathway.
Dhopeshwarkar A, Mackie K.
J Pharmacol Exp Ther · research-article; journal article; research support, n.i.h., extramural · DOI 10.1124/jpet.116.232561JWH-133, a Selective Cannabinoid CB₂ Receptor Agonist, Exerts Toxic Effects on Neuroblastoma SH-SY5Y Cells.
Wojcieszak J, Krzemień W, Zawilska JB.
J Mol Neurosci · research support, non-u.s. gov't; journal article · DOI 10.1007/s12031-016-0726-7Protective role of cannabinoid receptor 2 activation in galactosamine/lipopolysaccharide-induced acute liver failure through regulation of macrophage polarization and microRNAs.
Tomar S, Zumbrun EE, Nagarkatti M, Nagarkatti PS.
J Pharmacol Exp Ther · research-article; research support, u.s. gov't, non-p.h.s.; journal article; research support, n.i.h., extramural · DOI 10.1124/jpet.114.220368Evaluation of the effects of Eserine and JWH-133 on brain dysfunction associated with experimental endotoxemia.
Gamal M, Moawad J, Rashed L, El-Eraky W, Saleh D, Lehmann C, Sharawy N.
J Neuroimmunol · journal article · DOI 10.1016/j.jneuroim.2015.02.008Increase of mesenchymal stem cell migration by cannabidiol via activation of p42/44 MAPK.
Schmuhl E, Ramer R, Salamon A, Peters K, Hinz B.
Biochem Pharmacol · journal article · DOI 10.1016/j.bcp.2013.11.016Treatment with CB2 agonist JWH-133 reduces histological features associated with erectile dysfunction in hypercholesterolemic mice.
Fraga-Silva RA, Costa-Fraga FP, Montecucco F, Faye Y, Savergnini SQ, Lenglet S, Mach F, Steffens S, Stergiopulos N, dos Santos RA, da Silva RF.
Clin Dev Immunol · research support, non-u.s. gov't; research-article; journal article · DOI 10.1155/2013/263846Functional relevance of the cannabinoid receptor 2 - heme oxygenase pathway: a novel target for the attenuation of portal hypertension.
Steib CJ, Gmelin L, Pfeiler S, Schewe J, Brand S, Göke B, Gerbes AL.
Life Sci · research support, non-u.s. gov't; journal article · DOI 10.1016/j.lfs.2013.08.018