Using network pharmacology to discover potential drugs for hypertrophic scars.
Zhang Y, Li X, Yu Q, Lv X, Li C, Wang L, Liu Y, Wang Q, Yang Z, Fu X, Xiao R.
Br J Dermatol · journal article · DOI 10.1093/bjd/ljae234 PUBLICATION REGISTRY
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Publications in the selection
34 hitsHepatocyte growth factor promotes retinal pigment epithelium cell activity through MET/AKT signaling pathway.
Zhou SR, Zhu YS, Yuan WT, Pan XY, Wang T, Chen XD.
Int J Ophthalmol · research-article; journal article · DOI 10.18240/ijo.2024.05.03Hypoxia preconditioning of human amniotic mesenchymal stem cells enhances proliferation and migration and promotes their homing via the HGF/C-MET signaling axis to augment the repair of acute liver failure.
Wang Q, Li Y, Yuan H, Peng L, Dai Z, Sun Y, Liu R, Li W, Li J, Zhu C.
Tissue Cell · journal article · DOI 10.1016/j.tice.2024.102326The anti-tumor effects of AZD4547 on ovarian cancer cells: differential responses based on c-Met and FGF19/FGFR4 expression.
Lee YY, Ryu JY, Cho YJ, Choi JY, Choi JJ, Choi CH, Sa JK, Hwang JR, Lee JW.
Cancer Cell Int · research-article; journal article · DOI 10.1186/s12935-024-03235-2β<sub>2</sub>-adrenergic receptor promotes liver regeneration partially through crosstalk with c-met.
Tao X, Chen C, Chen Y, Zhang L, Hu J, Yu H, Liang M, Fu Q, Huang K.
Cell Death Dis · research support, non-u.s. gov't; research-article; journal article · DOI 10.1038/s41419-022-04998-0EGFR Alterations Influence the Cetuximab Treatment Response and c-MET Tyrosine-Kinase Inhibitor Sensitivity in Experimental Head and Neck Squamous Cell Carcinomas.
Nelhűbel GA, Cserepes M, Szabó B, Türk D, Kárpáti A, Kenessey I, Rásó E, Barbai T, Hegedűs Z, László V, Szokol B, Dobos J, Őrfi L, Tóvári J.
Pathol Oncol Res · research-article; journal article · DOI 10.3389/pore.2021.620256Hepatocyte growth factor overexpression promotes osteoclastogenesis and exacerbates bone loss in CIA mice.
Huang C, Zheng Y, Bai J, Shi C, Shi X, Shan H, Zhou X.
J Orthop Translat · research-article; journal article · DOI 10.1016/j.jot.2020.10.011CUL4B promotes aggressive phenotypes of renal cell carcinoma via upregulating c-Met expression.
Chen S, Wang Y, Chen L, Xia Y, Cui J, Wang W, Jiang X, Wang J, Zhu Y, Sun S, Zou Y, Gong Y, Shi B.
Int J Biochem Cell Biol · research support, non-u.s. gov't; journal article · DOI 10.1016/j.biocel.2020.105887Inhibition of c-MET increases the antitumour activity of PARP inhibitors in gastric cancer models.
Koustas E, Karamouzis MV, Sarantis P, Schizas D, Papavassiliou AG.
J Cell Mol Med · research support, non-u.s. gov't; research-article; journal article · DOI 10.1111/jcmm.15655Delayed recanalization after MCAO ameliorates ischemic stroke by inhibiting apoptosis via HGF/c-Met/STAT3/Bcl-2 pathway in rats.
Tang H, Gamdzyk M, Huang L, Gao L, Lenahan C, Kang R, Tang J, Xia Y, Zhang JH.
Exp Neurol · retracted publication; research support, non-u.s. gov't; journal article; research support, n.i.h., extramural · DOI 10.1016/j.expneurol.2020.113359Suppression of c-MET overcomes erlotinib resistance in tongue cancer cells.
Huang K, Liu D.
Onco Targets Ther · research-article; journal article · DOI 10.2147/ott.s167936Met receptor inhibitor SU11274 localizes in the endoplasmic reticulum.
Wiest EJ, Smith HJ, Hollingsworth MA.
Biochem Biophys Res Commun · research-article; research support, u.s. gov't, non-p.h.s.; journal article; research support, n.i.h., extramural · DOI 10.1016/j.bbrc.2018.05.034Differential responsiveness of MET inhibition in non-small-cell lung cancer with altered CBL.
Tan YC, Mirzapoiazova T, Won BM, Zhu L, Srivastava MK, Vokes EE, Husain AN, Batra SK, Sharma S, Salgia R.
Sci Rep · research-article; journal article · DOI 10.1038/s41598-017-09078-4Tyrosine kinase inhibitor SU11274 increased tumorigenicity and enriched for melanoma-initiating cells by bioenergetic modulation.
Kucerova L, Demkova L, Skolekova S, Bohovic R, Matuskova M.
BMC Cancer · research support, non-u.s. gov't; research-article; journal article · DOI 10.1186/s12885-016-2341-yElevated hepatocyte growth factor expression as an autocrine c-Met activation mechanism in acquired resistance to sorafenib in hepatocellular carcinoma cells.
Firtina Karagonlar Z, Koc D, Iscan E, Erdal E, Atabey N.
Cancer Sci · research support, non-u.s. gov't; research-article; journal article · DOI 10.1111/cas.12891SU11274 suppresses proliferation and motility of pancreatic cancer cells.
Tomizawa M, Shinozaki F, Motoyoshi Y, Sugiyama T, Yamamoto S, Ishige N.
Oncol Lett · research-article; journal article · DOI 10.3892/ol.2015.3452Co-culture of hepatocellular carcinoma cells and human umbilical endothelial cells damaged by SU11274.
Tomizawa M, Shinozaki F, Motoyoshi Y, Sugiyama T, Yamamoto S, Ishige N.
Biomed Rep · research-article; journal article · DOI 10.3892/br.2014.361Effect of c-Met inhibitor SU11274 on human colon cancer cell growth.
Gao SH, Liu C, Wei J, Feng Y.
Chin Med J (Engl) · research support, non-u.s. gov't; journal articlec-Met inhibitors.
Mughal A, Aslam HM, Sheikh A, Khan AM, Saleem S.
Infect Agent Cancer · letter; journal article · DOI 10.1186/1750-9378-8-13Study of critical role of c-Met and its inhibitor SU11274 in colorectal carcinoma.
Gao W, Bing X, Li M, Yang Z, Li Y, Chen H.
Med Oncol · research support, non-u.s. gov't; journal article · DOI 10.1007/s12032-013-0546-3Synergistic effect of afatinib with su11274 in non-small cell lung cancer cells resistant to gefitinib or erlotinib.
Chen G, Noor A, Kronenberger P, Teugels E, Umelo IA, De Grève J.
PLoS One · research support, non-u.s. gov't; research-article; journal article · DOI 10.1371/journal.pone.0059708Sorting nexin 2-mediated membrane trafficking of c-Met contributes to sensitivity of molecular-targeted drugs.
Ogi S, Fujita H, Kashihara M, Yamamoto C, Sonoda K, Okamoto I, Nakagawa K, Ohdo S, Tanaka Y, Kuwano M, Ono M.
Cancer Sci · research support, non-u.s. gov't; research-article; journal article · DOI 10.1111/cas.12117c-Met inhibitor SU11274 enhances the response of the prostate cancer cell line DU145 to ionizing radiation.
Yu H, Li X, Sun S, Gao X, Zhou D.
Biochem Biophys Res Commun · research support, non-u.s. gov't; journal article · DOI 10.1016/j.bbrc.2012.09.117Activated O2(•−) and H2O2 mediated cell survival in SU11274-treated non-small-cell lung cancer A549 cells via c-Met-PI3K-Akt and c-Met-Grb2/SOS-Ras-p38 pathways.
Liu Y, Shi QF, Ye YC, Tashiro S, Onodera S, Ikejima T.
J Pharmacol Sci · journal article · DOI 10.1254/jphs.12048fpActivation of ERK-p53 and ERK-mediated phosphorylation of Bcl-2 are involved in autophagic cell death induced by the c-Met inhibitor SU11274 in human lung cancer A549 cells.
Liu Y, Yang Y, Ye YC, Shi QF, Chai K, Tashiro S, Onodera S, Ikejima T.
J Pharmacol Sci · research support, non-u.s. gov't; journal article · DOI 10.1254/jphs.11181fpInhibition of phosphorylated c-Met in rhabdomyosarcoma cell lines by a small molecule inhibitor SU11274.
Hou J, Dong J, Sun L, Geng L, Wang J, Zheng J, Li Y, Bridge J, Hinrichs SH, Ding SJ.
J Transl Med · research support, non-u.s. gov't; research-article; journal article; research support, n.i.h., extramural · DOI 10.1186/1479-5876-9-64Effect of c-Met inhibitor SU11274 on hepatocellular carcinoma cell growth.
Inagaki Y, Qi F, Gao J, Qu X, Hasegawa K, Sugawara Y, Tang W, Kokudo N.
Biosci Trends · research support, non-u.s. gov't; journal article · DOI 10.5582/bst.2011.v5.2.52Inhibition of c-Met with the specific small molecule tyrosine kinase inhibitor SU11274 decreases growth and metastasis formation of experimental human melanoma.
Kenessey I, Keszthelyi M, Krámer Z, Berta J, Adám A, Dobos J, Mildner M, Flachner B, Cseh S, Barna G, Szokol B, Orfi L, Kéri G, Döme B, Klepetko W, Tímár J, Tóvári J.
Curr Cancer Drug Targets · journal article · DOI 10.2174/156800910791190184Differential inhibition sensitivities of MET mutants to the small molecule inhibitor SU11274.
Zimmer Y, Vaseva AV, Medová M, Streit B, Blank-Liss W, Greiner RH, Schiering N, Aebersold DM.
Cancer Lett · research support, non-u.s. gov't; journal article · DOI 10.1016/j.canlet.2009.08.017Dual MET-EGFR combinatorial inhibition against T790M-EGFR-mediated erlotinib-resistant lung cancer.
Tang Z, Du R, Jiang S, Wu C, Barkauskas DS, Richey J, Molter J, Lam M, Flask C, Gerson S, Dowlati A, Liu L, Lee Z, Halmos B, Wang Y, Kern JA, Ma PC.
Br J Cancer · research support, non-u.s. gov't; research-article; research support, u.s. gov't, non-p.h.s.; journal article; research support, n.i.h., extramural · DOI 10.1038/sj.bjc.6604559