Perfluorohexyloctane Ophthalmic Solution: A Review in Dry Eye Disease.
Zhuang-Yan A, Syed YY.
Drugs · review; journal article · DOI 10.1007/s40265-024-02016-5 PUBLICATION REGISTRY
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32 hitsManaging Dry Eye Disease with Novel Medications: Mechanism, Study Validity, Safety, Efficacy, and Practical Application.
Wong JC, Barak A.
Pharmacy (Basel) · review-article; review; journal article · DOI 10.3390/pharmacy12010019Perfluorohexyloctane ophthalmic solution (Miebo) for dry eye disease.
Författaruppgift saknas
Med Lett Drugs Ther · journal article · DOI 10.58347/tml.2024.1694cLong-Term Safety and Efficacy of Perfluorohexyloctane Ophthalmic Solution for the Treatment of Patients With Dry Eye Disease: The KALAHARI Study.
Protzko EE, Segal BA, Korenfeld MS, Krösser S, Vittitow JL.
Cornea · clinical trial, phase iii; research-article; multicenter study; randomized controlled trial; journal article · DOI 10.1097/ico.0000000000003418A review of the first anti-evaporative prescription treatment for dry eye disease: perfluorohexyloctane ophthalmic solution.
Sheppard JD, Evans DG, Protzko EE.
Am J Manag Care · research support, non-u.s. gov't; review; journal article · DOI 10.37765/ajmc.2023.89464Further contribution to the discussion on perfluorohexyloctane eye drops in dry eye disease.
Jung V, Krösser S, Burian G, Grillenberger R, Korward J, Roesky C.
Sci Total Environ · letter · DOI 10.1016/j.scitotenv.2023.168040Influence of perfluorohexyloctane (Evotears®) on higher order aberrations.
Saad A, Frings A.
Int Ophthalmol · research-article; journal article · DOI 10.1007/s10792-023-02905-wPerfluorohexyloctane in dry eye disease: A systematic review of its efficacy and safety as a novel therapeutic agent.
Ballesteros-Sánchez A, De-Hita-Cantalejo C, Sánchez-González MC, Jansone-Langine Z, de Sotomayor MA, Culig J, Sánchez-González JM.
Ocul Surf · systematic review; journal article · DOI 10.1016/j.jtos.2023.10.001Addressing excessive evaporation: an unmet need in dry eye disease.
Karpecki PM, Nichols KK, Sheppard JD.
Am J Manag Care · research support, non-u.s. gov't; journal article · DOI 10.37765/ajmc.2023.89448Perfluorohexyloctane: Do we really need a PFAS for the treatment of Dry Eye Disease?
García-Blasco C, Domingo-Echaburu S, Orive G, Lertxundi U.
Sci Total Environ · journal article · DOI 10.1016/j.scitotenv.2023.165936Topical ocular protein delivery based on protein powder suspensions in semifluorinated alkanes.
Marschall C, Filster J, Witt M, Hauptmeier B, Frieß W.
Eur J Pharm Biopharm · journal article · DOI 10.1016/j.ejpb.2023.06.014In Vitro Inhibition of Evaporation with Perfluorohexyloctane, an Eye Drop for Dry Eye Disease.
Vittitow J, Kissling R, DeCory H, Borchman D.
Curr Ther Res Clin Exp · research-article; journal article · DOI 10.1016/j.curtheres.2023.100704Oxygen-Carrying Capacity of Perfluorohexyloctane, a Novel Eye Drop for Dry Eye Disease.
Stolowich N, Vittitow J, Kissling R, Borchman D.
Curr Ther Res Clin Exp · brief-report; journal article · DOI 10.1016/j.curtheres.2023.100705[Topical application of perfluorohexyloctane eye drops-Compatible with sustainability?]
Ibelshäuser I.
Ophthalmologie · letter · DOI 10.1007/s00347-023-01866-wWill the Long-Named Perfluorohexyloctane Produce Long-lasting Improvements in Patients With Meibomian Gland Disease?
Seitzman GD, Lietman TM.
JAMA Ophthalmol · comment; journal article · DOI 10.1001/jamaophthalmol.2023.0399Perfluorohexyloctane Eye Drops for Dry Eye Disease Associated With Meibomian Gland Dysfunction in Chinese Patients: A Randomized Clinical Trial.
Tian L, Gao Z, Zhu L, Shi X, Zhao S, Gu H, Xu G, Wang L, Dai H, Zhang H, Jin X, Ma K, Xu Y, Ma L, Pei C, Ke B, Krösser S, Zhang Y, Jie Y.
JAMA Ophthalmol · research support, non-u.s. gov't; research-article; journal article · DOI 10.1001/jamaophthalmol.2023.0270NOV03 for Signs and Symptoms of Dry Eye Disease Associated With Meibomian Gland Dysfunction: The Randomized Phase 3 MOJAVE Study.
Sheppard JD, Kurata F, Epitropoulos AT, Krösser S, Vittitow JL, MOJAVE Study Group.
Am J Ophthalmol · clinical trial, phase iii; research support, non-u.s. gov't; randomized controlled trial; journal article · DOI 10.1016/j.ajo.2023.03.008Dry Eye Disease Associated with Meibomian Gland Dysfunction: Focus on Tear Film Characteristics and the Therapeutic Landscape.
Sheppard JD, Nichols KK.
Ophthalmol Ther · review-article; review; journal article · DOI 10.1007/s40123-023-00669-1The influence of a mineral oil cationic nanoemulsion or perfluorohexyloctane on the tear film lipid layer and higher order aberrations.
Habbe KJ, Frings A, Saad A, Geerling G.
PLoS One · clinical trial; research support, non-u.s. gov't; research-article; journal article · DOI 10.1371/journal.pone.0279977NOV03 for Dry Eye Disease Associated with Meibomian Gland Dysfunction: Results of the Randomized Phase 3 GOBI Study.
Tauber J, Berdy GJ, Wirta DL, Krösser S, Vittitow JL, GOBI Study Group.
Ophthalmology · clinical trial, phase iii; multicenter study; randomized controlled trial; journal article · DOI 10.1016/j.ophtha.2022.12.021Use of Perfluorohexyloctane for Preservation of Rat Liver After Circulatory Death and a Prolonged Cold Preservation Model for Hepatocyte Transplantation.
Matsumura M, Imura T, Inagaki A, Ogasawara H, Miyagi S, Ohashi K, Unno M, Kamei T, Goto M.
Transpl Int · letter · DOI 10.3389/ti.2022.10659Deciphering the Action of Perfluorohexyloctane Eye Drops to Reduce Ocular Discomfort and Pain.
Delicado-Miralles M, Velasco E, Díaz-Tahoces A, Gallar J, Acosta MC, Aracil-Marco A.
Front Med (Lausanne) · research-article; journal article · DOI 10.3389/fmed.2021.709712A Randomized Clinical Study (SEECASE) to Assess Efficacy, Safety, and Tolerability of NOV03 for Treatment of Dry Eye Disease.
Tauber J, Wirta DL, Sall K, Majmudar PA, Willen D, Krösser S, SEECASE study group.
Cornea · clinical trial, phase ii; comparative study; research-article; multicenter study; randomized controlled trial; journal article · DOI 10.1097/ico.0000000000002622VEGF Trap<sub>R1R2</sub> Suspended in the Semifluorinated Alkane F6H8 Inhibits Inflammatory Corneal Hem- and Lymphangiogenesis.
Le VNH, Hos D, Hou Y, Witt M, Barkovskiy M, Bock F, Cursiefen C.
Transl Vis Sci Technol · research-article; journal article · DOI 10.1167/tvst.9.11.15Effects and safety of perfluorohexyloctane on the eye surface and corneal endothelium.
Mateo Orobia AJ, Blasco-Martinez A, Rodríguez-Ausín P, Pablo Júlvez LE, Güemes Villahoz N, Del Prado Sanz E, Satué Palacián M, Benítez-Del-Castillo JM.
Arch Soc Esp Oftalmol (Engl Ed) · journal article · DOI 10.1016/j.oftal.2020.05.016Interactions of Perfluorohexyloctane With Polyethylene and Polypropylene Pharmaceutical Packaging Materials.
Falk YZ, Runnsjö A, Pettigrew A, Scherer D, Engblom J, Kocherbitov V.
J Pharm Sci · research support, non-u.s. gov't; journal article · DOI 10.1016/j.xphs.2020.03.026Influence of Perfluorohexyloctane Eye Drops on Tear Film Thickness in Patients with Mild to Moderate Dry Eye Disease: A Randomized Controlled Clinical Trial.
Schmidl D, Bata AM, Szegedi S, Aranha Dos Santos V, Stegmann H, Fondi K, Krösser S, Werkmeister RM, Schmetterer L, Garhöfer G.
J Ocul Pharmacol Ther · research support, non-u.s. gov't; randomized controlled trial; journal article · DOI 10.1089/jop.2019.0092Impact of different emulsifiers on biocompatibility and inflammatory potential of Perfluorohexyloctane (F6H8) emulsions for new intravenous drug delivery systems.
Tsagogiorgas C, Anger F, Beck G, Breedijk A, Yard B, Hoeger S.
Drug Des Devel Ther · research-article; journal article · DOI 10.2147/dddt.s195954Preclinical studies evaluating the effect of semifluorinated alkanes on ocular surface and tear fluid dynamics.
Agarwal P, Khun D, Krösser S, Eickhoff K, Wells FS, Willmott GR, Craig JP, Rupenthal ID.
Ocul Surf · research support, non-u.s. gov't; journal article · DOI 10.1016/j.jtos.2019.02.010Evaluation of pharmacokinetic properties and anaesthetic effects of propofol in a new perfluorohexyloctane (F6H8) emulsion in rats--A comparative study.
Tsagogiorgas C, Theisinger S, Heesch E, Krebs J, Holm R, Beck G, Yard B.
Int J Pharm · comparative study; research support, non-u.s. gov't; journal article · DOI 10.1016/j.ijpharm.2015.03.037