Cytotoxic constituents from Hyptis verticillata.
Novelo M, Cruz JG, Hernández L, Pereda-Miranda R, Chai H, Mar W, Pezzuto JM.
J Nat Prod · research support, non-u.s. gov't; journal article · DOI 10.1021/np50100a011 PUBLICATION REGISTRY
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Publikationer som ChEBI hänvisar till för vinblastine. Visa hela publikationsregistret
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50 hitsDrug absorption limited by P-glycoprotein-mediated secretory drug transport in human intestinal epithelial Caco-2 cell layers.
Hunter J, Hirst BH, Simmons NL.
Pharm Res · research support, non-u.s. gov't; journal article · DOI 10.1023/a:1018972102702Bisamides from Aglaia species: structure analysis and potential to reverse drug resistance with cultured cells.
Saifah E, Puripattanavong J, Likhitwitayawuid K, Cordell GA, Chai H, Pezzuto JM.
J Nat Prod · research support, u.s. gov't, p.h.s.; journal article · DOI 10.1021/np50094a004Transport of digoxin by human P-glycoprotein expressed in a porcine kidney epithelial cell line (LLC-PK1).
Tanigawara Y, Okamura N, Hirai M, Yasuhara M, Ueda K, Kioka N, Komano T, Hori R.
J Pharmacol Exp Ther · journal article · DOI 10.1016/s0022-3565(25)10423-0Metabolism of the Catharanthus alkaloids: from Streptomyces griseus to monoamine oxidase B.
Rosazza JP, Duffel MW, el-Marakby S, Ahn SH.
J Nat Prod · research support, u.s. gov't, p.h.s.; review; journal article · DOI 10.1021/np50081a001DNA as an affinity probe useful in the detection and isolation of biologically active natural products.
Pezzuto JM, Che CT, McPherson DD, Zhu JP, Topcu G, Erdelmeier CA, Cordell GA.
J Nat Prod · research support, u.s. gov't, p.h.s.; research support, non-u.s. gov't; journal article · DOI 10.1021/np50078a006New alpha-amino phosphonic acid derivatives of vinblastine: chemistry and antitumor activity.
Lavielle G, Hautefaye P, Schaeffer C, Boutin JA, Cudennec CA, Pierré A.
J Med Chem · journal article · DOI 10.1021/jm00111a012Evaluation of natural products as inhibitors of human immunodeficiency virus type 1 (HIV-1) reverse transcriptase.
Tan GT, Pezzuto JM, Kinghorn AD, Hughes SH.
J Nat Prod · research support, u.s. gov't, p.h.s.; research support, non-u.s. gov't; journal article · DOI 10.1021/np50073a012ATP-dependent primary active transport of cysteinyl leukotrienes across liver canalicular membrane. Role of the ATP-dependent transport system for glutathione S-conjugates.
Ishikawa T, Müller M, Klünemann C, Schaub T, Keppler D.
J Biol Chem · journal article · DOI 10.1016/s0021-9258(17)30655-5Vinblastine and vincristine are inhibitors of monoamine oxidase B.
Son JK, Rosazza PN, Duffel MW.
J Med Chem · research support, u.s. gov't, p.h.s.; journal article · DOI 10.1021/jm00169a002Structure-activity relationships of antineoplastic agents in multidrug resistance.
Selassie CD, Hansch C, Khwaja TA.
J Med Chem · journal article · DOI 10.1021/jm00169a014Chalcones: a new class of antimitotic agents.
Edwards ML, Stemerick DM, Sunkara PS.
J Med Chem · comparative study; journal article · DOI 10.1021/jm00169a021In vitro metabolic transformations of vinblastine: oxidations catalyzed by human ceruloplasmin.
Elmarakby SA, Duffel MW, Rosazza JP.
J Med Chem · research support, u.s. gov't, p.h.s.; journal article · DOI 10.1021/jm00129a023A mammalian cell agar-diffusion assay for the detection of toxic compounds.
Burres NS, Hunter JE, Wright AE.
J Nat Prod · journal article · DOI 10.1021/np50063a010In vitro metabolic transformations of vinblastine: oxidations catalyzed by peroxidase.
Elmarakby SA, Duffel MW, Goswami A, Sariaslani FS, Rosazza JP.
J Med Chem · research support, u.s. gov't, p.h.s.; journal article · DOI 10.1021/jm00123a030Vinblastin-23-oyl amino acid derivatives: chemistry, physicochemical data, toxicity, and antitumor activities against P388 and L1210 leukemias.
Bhushana Rao KS, Collard MP, Dejonghe JP, Atassi G, Hannart JA, Trouet A.
J Med Chem · comparative study; research support, non-u.s. gov't; journal article · DOI 10.1021/jm00146a017Bis(bioreductive) alkylating agents: synthesis and biological activity in a nude mouse human carcinoma model.
Witiak DT, Kamat PL, Allison DL, Liebowitz SM, Glaser R, Holliday JE, Moeschberger ML, Schaller JP.
J Med Chem · research support, u.s. gov't, p.h.s.; research support, non-u.s. gov't; journal article · DOI 10.1021/jm00366a004UV-mediated genotoxicity of furanoquinoline and of certain tryptophan-derived alkaloids.
Towers GH, Abramowski Z.
J Nat Prod · research support, non-u.s. gov't; journal article · DOI 10.1021/np50028a027Catharanthus alkaloids, XXXVIII. Confirming structural evidence and antineoplastic activity of the bisindole alkaloids leurosine-N'b-oxide (pleurosine), roseadine and vindolicine from Catharanthus roseus.
El-Sayed A, Handy GA, Cordell GA.
J Nat Prod · research support, u.s. gov't, p.h.s.; research support, non-u.s. gov't; journal article · DOI 10.1021/np50028a016Catharanthus alkaloids. XXXVI. Isolation of vincaleukoblastine (VLB) and periformyline from Catharanthus trichophyllus and pericyclivine from Catharanthus roseus.
Mukhopadhyay S, Cordell GA.
J Nat Prod · research support, u.s. gov't, p.h.s.; journal article · DOI 10.1021/np50015a017