PUBLICATION REGISTRY

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Publikationsdata från Europe PMC och PubMed. Följ källhänvisningar från ämnesregistret till originalpublikationerna.

Publikationer som ChEBI hänvisar till för trametinib. Visa hela publikationsregistret

A publication hit is not a conclusion. Publikationslistan visar bibliografiska uppgifter. Eventuella forskningsutdrag visas separat med originalunderlag. En källhänvisning visar inte i sig effekt, dosering eller säkerhet.

Publications in the selection

35 hits

Bibliografisk träff 2012-12-17

Phase II study of the MEK1/MEK2 inhibitor Trametinib in patients with metastatic BRAF-mutant cutaneous melanoma previously treated with or without a BRAF inhibitor.

Kim KB, Kefford R, Pavlick AC, Infante JR, Ribas A, Sosman JA, Fecher LA, Millward M, McArthur GA, Hwu P, Gonzalez R, Ott PA, Long GV, Gardner OS, Ouellet D, Xu Y, DeMarini DJ, Le NT, Patel K, Lewis KD.

J Clin Oncol · clinical trial, phase ii; research support, non-u.s. gov't; research-article; multicenter study; journal article · DOI 10.1200/jco.2012.43.5966

Bibliografisk träff 2012-12-01

Identification and characterization of a novel chemotype MEK inhibitor able to alter the phosphorylation state of MEK1/2.

Yoshida T, Kakegawa J, Yamaguchi T, Hantani Y, Okajima N, Sakai T, Watanabe Y, Nakamura M.

Oncotarget · comparative study; research-article; journal article · DOI 10.18632/oncotarget.747

Bibliografisk träff 2012-10-03

Cutaneous effects of BRAF inhibitor therapy: a case series.

Mattei PL, Alora-Palli MB, Kraft S, Lawrence DP, Flaherty KT, Kimball AB.

Ann Oncol · research support, non-u.s. gov't; journal article · DOI 10.1093/annonc/mds292

Bibliografisk träff 2012-01-14

Suppressive effect of an orally active MEK1/2 inhibitor in two different animal models for rheumatoid arthritis: a comparison with leflunomide.

Yamaguchi T, Kakefuda R, Tanimoto A, Watanabe Y, Tajima N.

Inflamm Res · comparative study; journal article · DOI 10.1007/s00011-011-0431-5

Bibliografisk träff 2011-04-26

Antitumor activities of JTP-74057 (GSK1120212), a novel MEK1/2 inhibitor, on colorectal cancer cell lines in vitro and in vivo.

Yamaguchi T, Kakefuda R, Tajima N, Sowa Y, Sakai T.

Int J Oncol · journal article · DOI 10.3892/ijo.2011.1015