Combinatorial design of nonsymmetrical cyclic urea inhibitors of aspartic protease of HIV-1.
Frecer V, Burello E, Miertus S.
Bioorg Med Chem · research support, non-u.s. gov't; journal article · DOI 10.1016/j.bmc.2005.06.026 PUBLICATION REGISTRY
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Publikationer som ChEBI hänvisar till för XV638. Visa hela publikationsregistret
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4 hitsCounteracting HIV-1 protease drug resistance: structural analysis of mutant proteases complexed with XV638 and SD146, cyclic urea amides with broad specificities.
Ala PJ, Huston EE, Klabe RM, Jadhav PK, Lam PY, Chang CH.
Biochemistry · journal article · DOI 10.1021/bi980386eMolecular recognition of cyclic urea HIV-1 protease inhibitors.
Ala PJ, DeLoskey RJ, Huston EE, Jadhav PK, Lam PY, Eyermann CJ, Hodge CN, Schadt MC, Lewandowski FA, Weber PC, McCabe DD, Duke JL, Chang CH.
J Biol Chem · journal article · DOI 10.1074/jbc.273.20.12325Cyclic urea amides: HIV-1 protease inhibitors with low nanomolar potency against both wild type and protease inhibitor resistant mutants of HIV.
Jadhav PK, Ala P, Woerner FJ, Chang CH, Garber SS, Anton ED, Bacheler LT.
J Med Chem · journal article · DOI 10.1021/jm960586t