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Publikationer som ChEBI hänvisar till för RGFP966. Visa hela publikationsregistret

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Publications in the selection

29 hits

Bibliografisk träff 2024-05-04

Histone deacetylase 3-specific inhibitor RGFP966 attenuates oxidative stress and inflammation after traumatic brain injury by activating the Nrf2 pathway.

Xu L, An T, Jia B, Wu Q, Shen J, Jin J, Liu J, Li C.

Burns Trauma · research-article; journal article · DOI 10.1093/burnst/tkad062

Bibliografisk träff 2024-05-01

Histone deacetylase-3 regulates the expression of the amyloid precursor protein and its inhibition promotes neuroregenerative pathways in Alzheimer's disease models.

Davis N, Taylor B, Abelleira-Hervas L, Karimian-Marnani N, Aleksynas R, Syed N, Di Giovanni S, Palmisano I, Sastre M.

FASEB J · research support, non-u.s. gov't; journal article · DOI 10.1096/fj.202301762rr

Bibliografisk träff 2023-11-22

Histone deacetylase 3 inhibition alleviates 2,4-dinitrochlorobenzene-induced atopic dermatitis via epigenetically upregulating Nrf2/HO-1 signaling pathway.

Zhou W, Zeng D, Liu S, Huang Y, Lv F, Zhou W.

Int Immunopharmacol · journal article · DOI 10.1016/j.intimp.2023.111107

Bibliografisk träff 2023-10-20

HDAC3 aberration-incurred GPX4 suppression drives renal ferroptosis and AKI-CKD progression.

Zhang L, Chen F, Dong J, Wang R, Bi G, Xu D, Zhang Y, Deng Y, Lin W, Yang Z, Cao W.

Redox Biol · research-article; journal article · DOI 10.1016/j.redox.2023.102939

Bibliografisk träff 2023-10-01

HDAC3 Contributes to Ischemic Stroke by Regulating Interferon Pathway.

Wang J, Yang M, Chen Y, Liu Y, Zhang H, Tian R, Zhao W, Zhu H, Wang S.

J Integr Neurosci · journal article · DOI 10.31083/j.jin2206156

Bibliografisk träff 2023-09-12

HDAC3 inhibition protects against peripheral and central alterations in an animal model of obesity.

Machado FR, Boeira SP, Bortolotto VC, Araujo SM, Poetini MR, Viana CE, Prigol M, Souza LC, de Gomes MG.

Pharmacol Rep · journal article · DOI 10.1007/s43440-023-00528-7

Bibliografisk träff 2023-07-12

RGFP966 exerts neuroprotective effect via HDAC3/Nrf2 pathway after surgical brain injury in rats.

Gu HP, Wu XF, Gong YT, Mu-Yao Wu, Shi MY, Sun YM, Dang BQ, Chen G.

Heliyon · research-article; journal article · DOI 10.1016/j.heliyon.2023.e18160

Bibliografisk träff 2022-12-21

Histone deacetylase 3 inhibitor attenuates diabetic retinopathy in mice.

Jiang Y, Luo B.

J Neurophysiol · journal article · DOI 10.1152/jn.00477.2022

Bibliografisk träff 2022-10-18

Histone Deacetylase 3 Inhibition Decreases Cerebral Edema and Protects the Blood-Brain Barrier After Stroke.

Lu H, Ashiqueali R, Lin CI, Walchale A, Clendaniel V, Matheson R, Fisher M, Lo EH, Selim M, Shehadah A.

Mol Neurobiol · research-article; journal article · DOI 10.1007/s12035-022-03083-z

Bibliografisk träff 2022-09-28

Histone Deacetylase 3 Governs β-Estradiol-ERα-Involved Endometrial Tumorigenesis via Inhibition of STING Transcription.

Chen G, Yan Q, Liu L, Wen X, Zeng H, Yin S.

Cancers (Basel) · research-article; journal article · DOI 10.3390/cancers14194718

Bibliografisk träff 2022-08-10

HDAC3 Inhibitor RGFP966 Ameliorated Neuroinflammation in the Cuprizone-Induced Demyelinating Mouse Model and LPS-Stimulated BV2 Cells by Downregulating the P2X7R/STAT3/NF-κB65/NLRP3 Activation.

Sun W, Zhang N, Liu B, Yang J, Loers G, Siebert HC, Wen M, Zheng X, Wang Z, Han J, Zhang R.

ACS Chem Neurosci · research support, non-u.s. gov't; journal article · DOI 10.1021/acschemneuro.1c00826

Bibliografisk träff 2021-10-16

RGFP966 is protective against lipopolysaccharide-induced depressive-like behaviors in mice by inhibiting neuroinflammation and microglial activation.

Bian HT, Xiao L, Liang L, Xie YP, Wang HL, Wang GH.

Int Immunopharmacol · journal article · DOI 10.1016/j.intimp.2021.108259

Bibliografisk träff 2021-02-18

HDAC3 inhibitor RGFP966 controls bacterial growth and modulates macrophage signaling during Mycobacterium tuberculosis infection.

Campo M, Heater S, Peterson GJ, Simmons JD, Skerrett SJ, Mayanja-Kizza H, Stein CM, Boom WH, Hawn TR.

Tuberculosis (Edinb) · research support, non-u.s. gov't; research-article; journal article; research support, n.i.h., extramural · DOI 10.1016/j.tube.2021.102062

Bibliografisk träff 2021-01-30

RGFP966, a selective HDAC3 inhibitor, ameliorates allergic and inflammatory responses in an OVA-induced allergic rhinitis mouse model.

Zhang W, Sun X, Ba G, Tang R, Lin H.

Int Immunopharmacol · journal article · DOI 10.1016/j.intimp.2021.107400

Bibliografisk träff 2020-12-24

Systemic HDAC3 inhibition ameliorates impairments in synaptic plasticity caused by simulated galactic cosmic radiation exposure in male mice.

Keiser AA, Kramár EA, Dong T, Shanur S, Pirodan M, Ru N, Acharya MM, Baulch JE, Limoli CL, Wood MA.

Neurobiol Learn Mem · research-article; research support, u.s. gov't, non-p.h.s.; journal article; research support, n.i.h., extramural · DOI 10.1016/j.nlm.2020.107367

Bibliografisk träff 2020-10-08

Corrigendum to "RGFP966, a histone deacetylase 3 inhibitor, promotes glioma stem cell differentiation by blocking TGF-β signaling via SMAD7" [Biochem. Pharmacol. 180 (2020) 114118].

Liang H, Wang Q, Wang D, Zheng H, Kalvakolanu DV, Lu H, Wen N, Chen X, Xu L, Ren J, Guo B, Zhang L.

Biochem Pharmacol · published erratum · DOI 10.1016/j.bcp.2020.114223

Bibliografisk träff 2020-09-01

RGFP966 inactivation of the YAP pathway attenuates cardiac dysfunction induced by prolonged hypothermic preservation.

Zheng XH, Wang LL, Zheng MZ, Zhong JJ, Chen YY, Shen YL.

J Zhejiang Univ Sci B · research-article; journal article · DOI 10.1631/jzus.b2000026

Bibliografisk träff 2020-08-13

Histone deacetylase 3-selective inhibitor RGFP966 ameliorates impaired glucose tolerance through β-cell protection.

Lei L, Bai G, Wang X, Liu S, Xia J, Wu S, Huan Y, Shen Z.

Toxicol Appl Pharmacol · research support, non-u.s. gov't; journal article · DOI 10.1016/j.taap.2020.115189

Bibliografisk träff 2020-06-23

RGFP966, a histone deacetylase 3 inhibitor, promotes glioma stem cell differentiation by blocking TGF-β signaling via SMAD7.

Liang H, Wang Q, Wang D, Zheng H, Kalvakolanu DV, Lu H, Wen N, Chen X, Xu L, Ren J, Guo B, Zhang L.

Biochem Pharmacol · research support, non-u.s. gov't; journal article · DOI 10.1016/j.bcp.2020.114118

Bibliografisk träff 2020-01-10

RGFP966 Suppresses Tumor Growth and Migration Through Inhibition of EGFR Expression in Hepatocellular Carcinoma Cells in vitro.

Yu X, Yang F, Jiang H, Fan L.

Drug Des Devel Ther · research-article; journal article · DOI 10.2147/dddt.s234871

Bibliografisk träff 2019-11-26

The HDAC3 inhibitor RGFP966 ameliorated ischemic brain damage by downregulating the AIM2 inflammasome.

Zhang MJ, Zhao QC, Xia MX, Chen J, Chen YT, Cao X, Liu Y, Yuan ZQ, Wang XY, Xu Y.

FASEB J · research support, non-u.s. gov't; journal article · DOI 10.1096/fj.201900394rrr

Retracted publication 2018-11-05

Inhibition of HDAC3 reverses Alzheimer's disease-related pathologies in vitro and in the 3xTg-AD mouse model.

Janczura KJ, Volmar CH, Sartor GC, Rao SJ, Ricciardi NR, Lambert G, Brothers SP, Wahlestedt C.

Proc Natl Acad Sci U S A · retracted publication; research support, non-u.s. gov't; research-article; journal article; research support, n.i.h., extramural · DOI 10.1073/pnas.1805436115

Bibliografisk träff 2018-05-31

Inhibition of histone deacetylase 3 via RGFP966 facilitates cortical plasticity underlying unusually accurate auditory associative cue memory for excitatory and inhibitory cue-reward associations.

Shang A, Bylipudi S, Bieszczad KM.

Behav Brain Res · research support, non-u.s. gov't; journal article; research support, n.i.h., extramural · DOI 10.1016/j.bbr.2018.05.036

Bibliografisk träff 2017-12-06

Targeting HDAC3 Activity with RGFP966 Protects Against Retinal Ganglion Cell Nuclear Atrophy and Apoptosis After Optic Nerve Injury.

Schmitt HM, Schlamp CL, Nickells RW.

J Ocul Pharmacol Ther · research support, non-u.s. gov't; research-article; journal article; research support, n.i.h., extramural · DOI 10.1089/jop.2017.0059

Bibliografisk träff 2017-09-05

HDAC3 Inhibitor RGFP966 Modulates Neuronal Memory for Vocal Communication Signals in a Songbird Model.

Phan ML, Gergues MM, Mahidadia S, Jimenez-Castillo J, Vicario DS, Bieszczad KM.

Front Syst Neurosci · research-article; journal article · DOI 10.3389/fnsys.2017.00065

Bibliografisk träff 2016-03-31

The Effects of Pharmacological Inhibition of Histone Deacetylase 3 (HDAC3) in Huntington's Disease Mice.

Jia H, Wang Y, Morris CD, Jacques V, Gottesfeld JM, Rusche JR, Thomas EA.

PLoS One · research-article; journal article; research support, n.i.h., extramural · DOI 10.1371/journal.pone.0152498

Bibliografisk träff 2016-03-16

HDAC 3-selective inhibitor RGFP966 demonstrates anti-inflammatory properties in RAW 264.7 macrophages and mouse precision-cut lung slices by attenuating NF-κB p65 transcriptional activity.

Leus NG, van der Wouden PE, van den Bosch T, Hooghiemstra WTR, Ourailidou ME, Kistemaker LE, Bischoff R, Gosens R, Haisma HJ, Dekker FJ.

Biochem Pharmacol · research support, non-u.s. gov't; research-article; journal article · DOI 10.1016/j.bcp.2016.03.010

Bibliografisk träff 2015-09-01

Histone Deacetylase Inhibition via RGFP966 Releases the Brakes on Sensory Cortical Plasticity and the Specificity of Memory Formation.

Bieszczad KM, Bechay K, Rusche JR, Jacques V, Kudugunti S, Miao W, Weinberger NM, McGaugh JL, Wood MA.

J Neurosci · research support, non-u.s. gov't; research-article; journal article; research support, n.i.h., extramural · DOI 10.1523/jneurosci.0914-15.2015

Bibliografisk träff 2013-01-07

HDAC3-selective inhibitor enhances extinction of cocaine-seeking behavior in a persistent manner.

Malvaez M, McQuown SC, Rogge GA, Astarabadi M, Jacques V, Carreiro S, Rusche JR, Wood MA.

Proc Natl Acad Sci U S A · research support, non-u.s. gov't; research-article; journal article; research support, n.i.h., extramural · DOI 10.1073/pnas.1213364110