AG490 suppresses EPO-mediated activation of JAK2-STAT but enhances blood flow recovery in rats with critical limb ischemia.
Chai HT, Yip HK, Sun CK, Hsu SY, Leu S.
J Inflamm (Lond) · research-article; journal article · DOI 10.1186/s12950-016-0126-3 PUBLICATION REGISTRY
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12 hitsAnoikis-resistant cholangiocarcinoma cells display aggressive characteristics and increase STAT3 activation.
Huyen NT, Prachayasittikul V, Chan-On W.
J Hepatobiliary Pancreat Sci · journal article · DOI 10.1002/jhbp.354Combined administration of propranolol + AG490 offers better effects on portal hypertensive rats with cirrhosis.
Wang D, Wang Q, Yin J, Dong R, Wang Q, Du X, Lu J.
J Gastroenterol Hepatol · journal article · DOI 10.1111/jgh.13207High Glucose Induces Down-Regulated GRIM-19 Expression to Activate STAT3 Signaling and Promote Cell Proliferation in Cell Culture.
Li YG, Han BB, Li F, Yu JW, Dong ZF, Niu GM, Qing YW, Li JB, Wei M, Zhu W.
PLoS One · research support, non-u.s. gov't; research-article; journal article · DOI 10.1371/journal.pone.0153659Isolation and Expression Analysis of STAT Members from Synechogobius hasta and Their Roles in Leptin Affecting Lipid Metabolism.
Wu K, Tan XY, Wei CC, You WJ, Zhuo MQ, Song YF.
Int J Mol Sci · research support, non-u.s. gov't; research-article; journal article · DOI 10.3390/ijms17030406Protective mechanisms of berberine against experimental autoimmune myocarditis in a rat model.
Liu X, Zhang X, Ye L, Yuan H.
Biomed Pharmacother · research support, non-u.s. gov't; journal article · DOI 10.1016/j.biopha.2016.02.015Areca nut components stimulate ADAM17, IL-1α, PGE2 and 8-isoprostane production in oral keratinocyte: role of reactive oxygen species, EGF and JAK signaling.
Chang MC, Chan CP, Chen YJ, Hsien HC, Chang YC, Yeung SY, Jeng PY, Cheng RH, Hahn LJ, Jeng JH.
Oncotarget · research-article; journal article · DOI 10.18632/oncotarget.7621IL-6 mediates the signal pathway of JAK-STAT3-VEGF-C promoting growth, invasion and lymphangiogenesis in gastric cancer.
Zhao G, Zhu G, Huang Y, Zheng W, Hua J, Yang S, Zhuang J, Ye J.
Oncol Rep · research support, non-u.s. gov't; journal article · DOI 10.3892/or.2016.4544Leptin/LepRb in the Ventral Tegmental Area Mediates Anxiety-Related Behaviors.
Liu J, Guo M, Lu XY.
Int J Neuropsychopharmacol · research support, non-u.s. gov't; research-article; journal article; research support, n.i.h., extramural · DOI 10.1093/ijnp/pyv115The second window of desflurane-induced preconditioning is mediated by STAT3: role of Pim-1 kinase.
Stumpner J, Tischer-Zeitz T, Lotz C, Umminger J, Neuwirth A, Smul TM, Redel A, Kehl F, Roewer N, Lange M.
Acta Anaesthesiol Scand · research support, non-u.s. gov't; journal article · DOI 10.1111/aas.12587Novel protein kinase signaling systems regulating lifespan identified by small molecule library screening using Drosophila.
Spindler SR, Li R, Dhahbi JM, Yamakawa A, Sauer F.
PLoS One · research support, non-u.s. gov't; research-article; journal article · DOI 10.1371/journal.pone.0029782JAK2 tyrosine kinase inhibitor tyrphostin AG490 downregulates the mitogen-activated protein kinase (MAPK) and signal transducer and activator of transcription (STAT) pathways and induces apoptosis in myeloma cells.
De Vos J, Jourdan M, Tarte K, Jasmin C, Klein B.
Br J Haematol · research support, non-u.s. gov't; journal article · DOI 10.1046/j.1365-2141.2000.02127.x