Fangchinoline inhibits the proliferation of SPC-A-1 lung cancer cells by blocking cell cycle progression.
Luo X, Peng JM, Su LD, Wang DY, Yu YJ.
Exp Ther Med · research-article; journal article · DOI 10.3892/etm.2015.2915 PUBLICATION REGISTRY
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21 hitsInhibition on Proteasome β1 Subunit Might Contribute to the Anti-Cancer Effects of Fangchinoline in Human Prostate Cancer Cells.
Li D, Lu Y, Sun P, Feng LX, Liu M, Hu LH, Wu WY, Jiang BH, Yang M, Qu XB, Guo DA, Liu X.
PLoS One · research support, non-u.s. gov't; research-article; journal article · DOI 10.1371/journal.pone.0141681Fangchinoline suppresses the growth and invasion of human glioblastoma cells by inhibiting the kinase activity of Akt and Akt-mediated signaling cascades.
Guo B, Xie P, Su J, Zhang T, Li X, Liang G.
Tumour Biol · journal article · DOI 10.1007/s13277-015-3990-1Fangchinoline targets PI3K and suppresses PI3K/AKT signaling pathway in SGC7901 cells.
Tian F, Ding D, Li D.
Int J Oncol · retracted publication; research-article; journal article · DOI 10.3892/ijo.2015.2959Ultra high performance liquid chromatography with tandem mass spectrometry method for the determination of tetrandrine and fangchinoline in rat plasma after oral administration of Fangji Huangqi Tang and Stephania tetrandra S. Moore extracts.
Wang X, Liu X, Cai H, Pei K, Cao G, Xu X, Shi F, Cai B.
J Sep Sci · research support, non-u.s. gov't; journal article · DOI 10.1002/jssc.201401384Simultaneous Determination of Fangchinoline and Tetrandrine in Qi-Fang-Xi-Bi-Granules by RP-HPLC.
Lu X, Zhang R, Fu F, Shen J, Nian H, Wu T.
J Chromatogr Sci · research support, non-u.s. gov't; journal article · DOI 10.1093/chromsci/bmv016Fangchinoline as a kinase inhibitor targets FAK and suppresses FAK-mediated signaling pathway in A549.
Guo B, Su J, Zhang T, Wang K, Li X.
J Drug Target · journal article · DOI 10.3109/1061186x.2014.992898Tetrandrine and fangchinoline, bisbenzylisoquinoline alkaloids from Stephania tetrandra can reverse multidrug resistance by inhibiting P-glycoprotein activity in multidrug resistant human cancer cells.
Sun YF, Wink M.
Phytomedicine · research support, non-u.s. gov't; journal article · DOI 10.1016/j.phymed.2014.04.029Fangchinoline inhibits cell proliferation via Akt/GSK-3beta/ cyclin D1 signaling and induces apoptosis in MDA-MB-231 breast cancer cells.
Wang CD, Yuan CF, Bu YQ, Wu XM, Wan JY, Zhang L, Hu N, Liu XJ, Zu Y, Liu GL, Song FZ.
Asian Pac J Cancer Prev · research support, non-u.s. gov't; journal article · DOI 10.7314/apjcp.2014.15.2.769Fangchinoline induces G1 arrest in breast cancer cells through cell-cycle regulation.
Xing Z, Zhang Y, Zhang X, Yang Y, Ma Y, Pang D.
Phytother Res · research support, non-u.s. gov't; journal article · DOI 10.1002/ptr.4936Fangchinoline induces G0/G1 arrest by modulating the expression of CDKN1A and CCND2 in K562 human chronic myelogenous leukemia cells.
Wang Y, Chen J, Wang L, Huang Y, Leng Y, Wang G.
Exp Ther Med · research-article; journal article · DOI 10.3892/etm.2013.924Simultaneous determination of fangchinoline and tetrandrine in Stephania tetrandra S. Moore by using 1-alkyl-3-methylimidazolium-based ionic liquids as the RP-HPLC mobile phase additives.
Tang Y, Sun A, Liu R, Zhang Y.
Anal Chim Acta · research support, non-u.s. gov't; journal article · DOI 10.1016/j.aca.2013.01.001Effect of fangchinoline on root resorption during rat orthodontic tooth movement.
Bao X, Hu M, Zhang Y, Machibya F, Zhang Y, Jiang H, Yu D.
Korean J Orthod · research-article; journal article · DOI 10.4041/kjod.2012.42.3.138Fangchinoline inhibits human immunodeficiency virus type 1 replication by interfering with gp160 proteolytic processing.
Wan Z, Lu Y, Liao Q, Wu Y, Chen X.
PLoS One · research support, non-u.s. gov't; research-article; journal article · DOI 10.1371/journal.pone.0039225Fangchinoline induces autophagic cell death via p53/sestrin2/AMPK signalling in human hepatocellular carcinoma cells.
Wang N, Pan W, Zhu M, Zhang M, Hao X, Liang G, Feng Y.
Br J Pharmacol · research support, non-u.s. gov't; research-article; journal article · DOI 10.1111/j.1476-5381.2011.01349.xFangchinoline inhibits breast adenocarcinoma proliferation by inducing apoptosis.
Xing ZB, Yao L, Zhang GQ, Zhang XY, Zhang YX, Pang D.
Chem Pharm Bull (Tokyo) · research support, non-u.s. gov't; journal article · DOI 10.1248/cpb.59.1476Fangchinoline induced G1/S arrest by modulating expression of p27, PCNA, and cyclin D in human prostate carcinoma cancer PC3 cells and tumor xenograft.
Wang CD, Huang JG, Gao X, Li Y, Zhou SY, Yan X, Zou A, Chang JL, Wang YS, Yang GX, He GY.
Biosci Biotechnol Biochem · research support, non-u.s. gov't; journal article · DOI 10.1271/bbb.90490Antioxidant activity of bisbenzylisoquinoline alkaloids from Stephania rotunda: cepharanthine and fangchinoline.
Gülçin I, Elias R, Gepdiremen A, Chea A, Topal F.
J Enzyme Inhib Med Chem · research support, non-u.s. gov't; journal article · DOI 10.3109/14756360902932792Ionic liquid-based ultrasound-assisted extraction of fangchinoline and tetrandrine from Stephaniae tetrandrae.
Zhang L, Geng Y, Duan W, Wang D, Fu M, Wang X.
J Sep Sci · research support, non-u.s. gov't; evaluation study; journal article · DOI 10.1002/jssc.200900413Fangchinoline inhibits glutamate release from rat cerebral cortex nerve terminals (synaptosomes).
Lin TY, Lu CW, Tien LT, Chuang SH, Wang YR, Chang WH, Wang SJ.
Neurochem Int · research support, non-u.s. gov't; journal article · DOI 10.1016/j.neuint.2009.02.001[Determination of tetrandrine and fangchinoline in Radix Stephaniae tetrandrae and its preparation by nonaqueous capillary chromatography].
Li YQ, Chen XG, Qi YX, Li K, Jia BX, Liu CH, Cao ML.
Zhongguo Zhong Yao Za Zhi · journal article