DNA adduct formation of the food carcinogen 2-amino-3-methylimidazo[4,5- f]quinoline at the C-8 and N2 atoms of guanine.
Turesky RJ, Markovic J.
Chem Res Toxicol · journal article · DOI 10.1021/tx00042a007 PUBLICATION REGISTRY
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7 hitsEffects of human and rat glutathione S-transferases on the covalent DNA binding of the N-acetoxy derivatives of heterocyclic amine carcinogens in vitro: a possible mechanism of organ specificity in their carcinogenesis.
Lin D, Meyer DJ, Ketterer B, Lang NP, Kadlubar FF.
Cancer Res · journal article32P-postlabeling analysis of IQ, MeIQx and PhIP adducts formed in vitro in DNA and polynucleotides and found in vivo in hepatic DNA from IQ-, MeIQx- and PhIP-treated monkeys.
Snyderwine EG, Davis CD, Nouso K, Roller PP, Schut HA.
Carcinogenesis · research support, non-u.s. gov't; journal article · DOI 10.1093/carcin/14.7.138932P-postlabelling studies on the DNA adducts of the food mutagens/carcinogens IQ and PhIP--adduct formation in a chemical system, and by rat and human metabolism.
Kerdar RS, Fasshauer I, Probst M, Blum M, Meyer UA, Wild D.
IARC Sci Publ · research support, non-u.s. gov't; journal articleQuantitation of 2-amino-3-methylimidazo[4,5-f]quinoline and 2-amino-3,8-dimethylimidazo[4,5-f]quinoxaline DNA adducts in specific sequences using alkali or uvrABC excinuclease.
Nouso K, Bohr VA, Schut HA, Snyderwine EG.
Mol Carcinog · research support, non-u.s. gov't; journal article · DOI 10.1002/mc.2940070211Characterization of DNA adducts formed in vitro by reaction of N-hydroxy-2-amino-3-methylimidazo[4,5-f]quinoline and N-hydroxy-2-amino-3,8-dimethylimidazo[4,5-f]quinoxaline at the C-8 and N2 atoms of guanine.
Turesky RJ, Rossi SC, Welti DH, Lay JO, Kadlubar FF.
Chem Res Toxicol · journal article · DOI 10.1021/tx00028a005Reaction of N-hydroxylamine and N-acetoxy derivatives of 2-amino-3-methylimidazolo[4,5-f]quinoline with DNA. Synthesis and identification of N-(deoxyguanosin-8-yl)-IQ.
Snyderwine EG, Roller PP, Adamson RH, Sato S, Thorgeirsson SS.
Carcinogenesis · research support, non-u.s. gov't; journal article · DOI 10.1093/carcin/9.6.1061