The location, physiology, pathology of hippocampus Melatonin MT<sub>2</sub> receptor and MT<sub>2</sub>-selective modulators.
Feng Y, Jiang X, Liu W, Lu H.
Eur J Med Chem · review; journal article · DOI 10.1016/j.ejmech.2023.115888 PUBLICATION REGISTRY
Go to research.
Publikationsdata från Europe PMC och PubMed. Följ källhänvisningar från ämnesregistret till originalpublikationerna.
Publikationer som ChEBI hänvisar till för agomelatine. Visa hela publikationsregistret
A publication hit is not a conclusion. Publikationslistan visar bibliografiska uppgifter. Eventuella forskningsutdrag visas separat med originalunderlag. En källhänvisning visar inte i sig effekt, dosering eller säkerhet.
Publications in the selection
27 hitsA preclinical secondary pharmacology resource illuminates target-adverse drug reaction associations of marketed drugs.
Sutherland JJ, Yonchev D, Fekete A, Urban L.
Nat Commun · research support, non-u.s. gov't; research-article; journal article · DOI 10.1038/s41467-023-40064-9Development of indolealkylamine derivatives as potential multi-target agents for COVID-19 treatment.
Chauhan J, Cecon E, Labani N, Gbahou F, Real F, Bomsel M, Dubey KD, Das R, Dam J, Jockers R, Sen S.
Eur J Med Chem · research-article; journal article · DOI 10.1016/j.ejmech.2023.115152Synthesis and biological evaluation of paeoveitol D derivatives as new melatonin receptor agonists with antidepressant activities.
Li TZ, Hu J, Sun JJ, Huang XY, Geng CA, Liu SB, Zhang XM, Chen JJ.
RSC Med Chem · research-article; journal article · DOI 10.1039/d2md00156jDiscovery of <b>ACH-000143</b>: A Novel Potent and Peripherally Preferred Melatonin Receptor Agonist that Reduces Liver Triglycerides and Steatosis in Diet-Induced Obese Rats.
Ferreira MA, Azevedo H, Mascarello A, Segretti ND, Russo E, Russo V, Guimarães CRW.
J Med Chem · research support, non-u.s. gov't; journal article · DOI 10.1021/acs.jmedchem.0c00627Quinazoline and phthalazine derivatives as novel melatonin receptor ligands analogues of agomelatine.
Bolteau R, Descamps F, Ettaoussi M, Caignard DH, Delagrange P, Melnyk P, Yous S.
Eur J Med Chem · journal article · DOI 10.1016/j.ejmech.2020.112078Synthesis and biological evaluation of magnolol derivatives as melatonergic receptor agonists with potential use in depression.
Yang TH, Ma YB, Geng CA, Yan DX, Huang XY, Li TZ, Zhang XM, Chen JJ.
Eur J Med Chem · journal article · DOI 10.1016/j.ejmech.2018.07.027Synthesis and biological evaluation of new naphtho- and quinolinocyclopentane derivatives as potent melatoninergic (MT<sub>1</sub>/MT<sub>2</sub>) and serotoninergic (5-HT<sub>2C</sub>) dual ligands.
Duroux R, Rami M, Landagaray E, Ettaoussi M, Caignard DH, Delagrange P, Melnyk P, Yous S.
Eur J Med Chem · journal article · DOI 10.1016/j.ejmech.2017.10.025New quinolinic derivatives as melatonergic ligands: Synthesis and pharmacological evaluation.
Landagaray E, Ettaoussi M, Rami M, Boutin JA, Caignard DH, Delagrange P, Melnyk P, Berthelot P, Yous S.
Eur J Med Chem · journal article · DOI 10.1016/j.ejmech.2016.12.013Melatonergic ligands: Design, synthesis and pharmacological evaluation of novel series of naphthofuranic derivatives.
Landagaray E, Ettaoussi M, Duroux R, Boutin JA, Caignard DH, Delagrange P, Melnyk P, Berthelot P, Yous S.
Eur J Med Chem · research support, non-u.s. gov't; journal article · DOI 10.1016/j.ejmech.2015.12.047Novel N-Acetyl Bioisosteres of Melatonin: Melatonergic Receptor Pharmacology, Physicochemical Studies, and Phenotypic Assessment of Their Neurogenic Potential.
de la Fuente Revenga M, Fernández-Sáez N, Herrera-Arozamena C, Morales-García JA, Alonso-Gil S, Pérez-Castillo A, Caignard DH, Rivara S, Rodríguez-Franco MI.
J Med Chem · research support, non-u.s. gov't; journal article · DOI 10.1021/acs.jmedchem.5b00245Synthesis and biological evaluation of novel naphthalene compounds as potential antidepressant agents.
Ang W, Chen G, Xiong L, Chang Y, Pi W, Liu Y, Li C, Zheng J, Zhou L, Yang B, Deng Y, Yang S, Luo Y, Wei Y.
Eur J Med Chem · research support, non-u.s. gov't; journal article · DOI 10.1016/j.ejmech.2014.05.061Synthesis and evaluation of amide side-chain modified Agomelatine analogues as potential antidepressant-like agents.
Chang Y, Pi W, Ang W, Liu Y, Li C, Zheng J, Xiong L, Yang T, Luo Y.
Bioorg Med Chem Lett · research support, non-u.s. gov't; journal article · DOI 10.1016/j.bmcl.2014.02.065A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
Morgan RE, van Staden CJ, Chen Y, Kalyanaraman N, Kalanzi J, Dunn RT, Afshari CA, Hamadeh HK.
Toxicol Sci · journal article · DOI 10.1093/toxsci/kft176Synthesis of new N-(arylcyclopropyl)acetamides and N-(arylvinyl)acetamides as conformationally-restricted ligands for melatonin receptors.
Morellato L, Lefas-Le Gall M, Langlois M, Caignard DH, Renard P, Delagrange P, Mathé-Allainmat M.
Bioorg Med Chem Lett · journal article · DOI 10.1016/j.bmcl.2012.11.069Design, synthesis and pharmacological evaluation of new series of naphthalenic analogues as melatoninergic (MT1/MT2) and serotoninergic 5-HT2C dual ligands (I).
Ettaoussi M, Sabaouni A, Rami M, Boutin JA, Delagrange P, Renard P, Spedding M, Caignard DH, Berthelot P, Yous S.
Eur J Med Chem · research support, non-u.s. gov't; journal article · DOI 10.1016/j.ejmech.2012.01.027Design and synthesis of 4-arylpiperidinyl amide and N-arylpiperdin-3-yl-cyclopropane carboxamide derivatives as novel melatonin receptor ligands.
Li G, Zhou H, Jiang Y, Keim H, Topiol SW, Poda SB, Ren Y, Chandrasena G, Doller D.
Bioorg Med Chem Lett · journal article · DOI 10.1016/j.bmcl.2010.12.068Design, synthesis and pharmacological evaluation of novel naphthalenic derivatives as selective MT(1) melatoninergic ligands.
Mésangeau C, Pérès B, Descamps-François C, Chavatte P, Audinot V, Coumailleau S, Boutin JA, Delagrange P, Bennejean C, Renard P, Caignard DH, Berthelot P, Yous S.
Bioorg Med Chem · research support, non-u.s. gov't; journal article · DOI 10.1016/j.bmc.2010.04.008Synthesis of 3-phenylnaphthalenic derivatives as new selective MT(2) melatoninergic ligands.
Poissonnier-Durieux S, Ettaoussi M, Pérès B, Boutin JA, Audinot V, Bennejean C, Delagrange P, Caignard DH, Renard P, Berthelot P, Lesieur D, Yous S.
Bioorg Med Chem · journal article · DOI 10.1016/j.bmc.2008.08.052Design and synthesis of naphthalenic dimers as selective MT1 melatoninergic ligands.
Descamps-François C, Yous S, Chavatte P, Audinot V, Bonnaud A, Boutin JA, Delagrange P, Bennejean C, Renard P, Lesieur D.
J Med Chem · journal article · DOI 10.1021/jm0255872Synthesis of phenalene and acenaphthene derivatives as new conformationally restricted ligands for melatonin receptors.
Jellimann C, Mathé-Allainmat M, Andrieux J, Kloubert S, Boutin JA, Nicolas JP, Bennejean C, Delagrange P, Langlois M.
J Med Chem · journal article · DOI 10.1021/jm000922cMelatonergic properties of the (+)- and (-)-enantiomers of N-(4-methoxy-2,3-dihydro-1H-phenalen-2-yl)amide derivatives.
Jellimann C, Mathé-Allainmat M, Andrieux J, Renard P, Delagrange P, Langlois M.
J Med Chem · journal article · DOI 10.1021/jm9804937Melatonin receptor ligands: synthesis of new melatonin derivatives and comprehensive comparative molecular field analysis (CoMFA) study.
Mor M, Rivara S, Silva C, Bordi F, Plazzi PV, Spadoni G, Diamantini G, Balsamini C, Tarzia G, Fraschini F, Lucini V, Nonno R, Stankov BM.
J Med Chem · research support, non-u.s. gov't; journal article · DOI 10.1021/jm9810093Three-dimensional quantitative structure-activity relationship of melatonin receptor ligands: a comparative molecular field analysis study.
Sicsic S, Serraz I, Andrieux J, Brémont B, Mathé-Allainmat M, Poncet A, Shen S, Langlois M.
J Med Chem · research support, non-u.s. gov't; journal article · DOI 10.1021/jm960680+Design and synthesis of new naphthalenic derivatives as ligands for 2-[125I]iodomelatonin binding sites.
Langlois M, Brémont B, Shen S, Poncet A, Andrieux J, Sicsic S, Serraz I, Mathé-Allainmat M, Renard P, Delagrange P.
J Med Chem · journal article · DOI 10.1021/jm00012a004Synthesis and structure-activity relationships of novel naphthalenic and bioisosteric related amidic derivatives as melatonin receptor ligands.
Depreux P, Lesieur D, Mansour HA, Morgan P, Howell HE, Renard P, Caignard DH, Pfeiffer B, Delagrange P, Guardiola B.
J Med Chem · comparative study; journal article · DOI 10.1021/jm00046a006Novel naphthalenic ligands with high affinity for the melatonin receptor.
Yous S, Andrieux J, Howell HE, Morgan PJ, Renard P, Pfeiffer B, Lesieur D, Guardiola-Lemaitre B.
J Med Chem · journal article · DOI 10.1021/jm00086a018