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Publikationer som ChEBI hänvisar till för milnacipran. Visa hela publikationsregistret

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Publications in the selection

17 hits

Bibliografisk träff 2023-07-19

A preclinical secondary pharmacology resource illuminates target-adverse drug reaction associations of marketed drugs.

Sutherland JJ, Yonchev D, Fekete A, Urban L.

Nat Commun · research support, non-u.s. gov't; research-article; journal article · DOI 10.1038/s41467-023-40064-9

Bibliografisk träff 2021-02-19

Identification of Novel High-Affinity Substrates of OCT1 Using Machine Learning-Guided Virtual Screening and Experimental Validation.

Jensen O, Brockmöller J, Dücker C.

J Med Chem · journal article · DOI 10.1021/acs.jmedchem.0c02047

Bibliografisk träff 2019-06-03

Mapping human microbiome drug metabolism by gut bacteria and their genes.

Zimmermann M, Zimmermann-Kogadeeva M, Wegmann R, Goodman AL.

Nature · research support, non-u.s. gov't; research-article; journal article; research support, n.i.h., extramural · DOI 10.1038/s41586-019-1291-3

Bibliografisk träff 2016-10-29

Discovery of SMP-304, a novel benzylpiperidine derivative with serotonin transporter inhibitory activity and 5-HT<sub>1A</sub> weak partial agonistic activity showing the antidepressant-like effect.

Yoshinaga H, Masumoto S, Koyama K, Kinomura N, Matsumoto Y, Kato T, Baba S, Matsumoto K, Horisawa T, Oki H, Yabuuchi K, Kodo T.

Bioorg Med Chem · journal article · DOI 10.1016/j.bmc.2016.10.034

Bibliografisk träff 2016-03-03

DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.

Chen M, Suzuki A, Thakkar S, Yu K, Hu C, Tong W.

Drug Discov Today · review; journal article · DOI 10.1016/j.drudis.2016.02.015

Bibliografisk träff 2013-05-07

Discovery of a potent, dual serotonin and norepinephrine reuptake inhibitor.

Dreyfus N, Myers JK, Badescu VO, de Frutos O, de la Puente ML, Ding C, Filla SA, Fynboe K, Gernert DL, Heinz BA, Hemrick-Luecke SK, Johnson KW, Johnson MP, López P, Love PL, Martin LJ, Masquelin T, McCoy MJ, Mendiola J, Morrow D, Muhlhauser M, Pascual G, Perun TJ, Pfeifer LA, Phebus LA, Richards SJ, Rincón JA, Seest EP, Shah J, Shaojuan J, Simmons RM, Stephenson GA, Tromiczak EG, Thompson LK, Walter MW, Weber WW, Zarrinmayeh H, Thomas CE, Joshi E, Iyengar S, Johansson AM.

ACS Med Chem Lett · rapid-communication; journal article · DOI 10.1021/ml400049p

Bibliografisk träff 2012-12-22

A novel class of 3-(phenoxy-phenyl-methyl)-pyrrolidines as potent and balanced norepinephrine and serotonin reuptake inhibitors: synthesis and structure-activity relationships.

Van Orden LJ, Van Dyke PM, Saito DR, Church TJ, Chang R, Smith JA, Martin WJ, Jaw-Tsai S, Stangeland EL.

Bioorg Med Chem Lett · journal article · DOI 10.1016/j.bmcl.2012.12.061

Bibliografisk träff 2012-05-31

Excretion and metabolism of milnacipran in humans after oral administration of milnacipran hydrochloride.

Li F, Chin C, Wangsa J, Ho J.

Drug Metab Dispos · clinical trial; research support, non-u.s. gov't; journal article · DOI 10.1124/dmd.112.045120

Bibliografisk träff 2010-11-23

Control and measurement of plasma pH in equilibrium dialysis: influence on drug plasma protein binding.

Curran RE, Claxton CR, Hutchison L, Harradine PJ, Martin IJ, Littlewood P.

Drug Metab Dispos · research support, non-u.s. gov't; journal article · DOI 10.1124/dmd.110.036988

Bibliografisk träff 2010-10-21

Experimental solubility profiling of marketed CNS drugs, exploring solubility limit of CNS discovery candidate.

Alelyunas YW, Empfield JR, McCarthy D, Spreen RC, Bui K, Pelosi-Kilby L, Shen C.

Bioorg Med Chem Lett · journal article · DOI 10.1016/j.bmcl.2010.10.068

Bibliografisk träff 2008-11-01

Characterization of thien-2-yl 1S,2R-milnacipran analogues as potent norepinephrine/serotonin transporter inhibitors for the treatment of neuropathic pain.

Dyck B, Tamiya J, Jovic F, Pick RR, Bradbury MJ, O'Brien J, Wen J, Johns M, Madan A, Fleck BA, Foster AC, Li B, Zhang M, Tran JA, Vickers T, Grey J, Saunders J, Chen C.

J Med Chem · journal article · DOI 10.1021/jm8009537

Bibliografisk träff 2008-04-25

Studies on a series of milnacipran analogs containing a heteroaromatic group as potent norepinephrine and serotonin transporter inhibitors.

Vickers T, Dyck B, Tamiya J, Zhang M, Jovic F, Grey J, Fleck BA, Aparicio A, Johns M, Jin L, Tang H, Foster AC, Chen C.

Bioorg Med Chem Lett · journal article · DOI 10.1016/j.bmcl.2008.04.045

Bibliografisk träff 2008-04-15

Identification of 1S,2R-milnacipran analogs as potent norepinephrine and serotonin transporter inhibitors.

Tamiya J, Dyck B, Zhang M, Phan K, Fleck BA, Aparicio A, Jovic F, Tran JA, Vickers T, Grey J, Foster AC, Chen C.

Bioorg Med Chem Lett · journal article · DOI 10.1016/j.bmcl.2008.04.025

Bibliografisk träff 2008-01-09

Studies on the SAR and pharmacophore of milnacipran derivatives as monoamine transporter inhibitors.

Chen C, Dyck B, Fleck BA, Foster AC, Grey J, Jovic F, Mesleh M, Phan K, Tamiya J, Vickers T, Zhang M.

Bioorg Med Chem Lett · journal article · DOI 10.1016/j.bmcl.2008.01.011

Bibliografisk träff 2007-09-01

Hologram QSAR model for the prediction of human oral bioavailability.

Moda TL, Montanari CA, Andricopulo AD.

Bioorg Med Chem · research support, non-u.s. gov't; journal article · DOI 10.1016/j.bmc.2007.08.060

Bibliografisk träff 2005-10-01

Designed multiple ligands. An emerging drug discovery paradigm.

Morphy R, Rankovic Z.

J Med Chem · review; journal article · DOI 10.1021/jm058225d

Bibliografisk träff 2004-08-01

[Drug-induced liver injury; fourteenth updated edition of the bibliographic database of liver injuries and related drugs].

Biour M, Ben Salem C, Chazouillères O, Grangé JD, Serfaty L, Poupon R.

Gastroenterol Clin Biol · bibliography; journal article · DOI 10.1016/s0399-8320(04)95062-2