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Publications in the selection

14 hits

Bibliografisk träff 2023-07-19

A preclinical secondary pharmacology resource illuminates target-adverse drug reaction associations of marketed drugs.

Sutherland JJ, Yonchev D, Fekete A, Urban L.

Nat Commun · research support, non-u.s. gov't; research-article; journal article · DOI 10.1038/s41467-023-40064-9

Bibliografisk träff 2022-08-06

Design, synthesis, and antitumor study of a series of novel 1-Oxa-4-azaspironenone derivatives.

Yin H, Chen Y, Zhong Q, Zheng S, Wang G, He L.

Bioorg Med Chem Lett · research-article; journal article · DOI 10.1016/j.bmcl.2022.128925

Bibliografisk träff 2022-04-16

Design, synthesis, and evaluation of a novel series of mono-indolylbenzoquinones derivatives for the potential treatment of breast cancer.

Jia J, Yin H, Chen C, Hu M, Zhong Q, Zheng S, Zhang W, Li H, Xu L, Wang G, He L.

Eur J Med Chem · research-article; journal article · DOI 10.1016/j.ejmech.2022.114375

Bibliografisk träff 2020-11-21

Synthesis and anticancer activity evaluation of naphthalene-substituted triazole spirodienones.

Luo L, Jia JJ, Zhong Q, Zhong X, Zheng S, Wang G, He L.

Eur J Med Chem · research-article; journal article · DOI 10.1016/j.ejmech.2020.113039

Bibliografisk träff 2020-10-08

Comprehensive review for anticancer hybridized multitargeting HDAC inhibitors.

Bass AKA, El-Zoghbi MS, Nageeb EM, Mohamed MFA, Badr M, Abuo-Rahma GEA.

Eur J Med Chem · review; journal article · DOI 10.1016/j.ejmech.2020.112904

Bibliografisk träff 2020-09-17

Paradigm shift of "classical" HDAC inhibitors to "hybrid" HDAC inhibitors in therapeutic interventions.

Vaidya GN, Rana P, Venkatesh A, Chatterjee DR, Contractor D, Satpute DP, Nagpure M, Jain A, Kumar D.

Eur J Med Chem · review; journal article · DOI 10.1016/j.ejmech.2020.112844

Bibliografisk träff 2020-07-21

Design, synthesis, biological evaluation, QSAR analysis and molecular modelling of new thiazol-benzimidazoles as EGFR inhibitors.

Srour AM, Ahmed NS, Abd El-Karim SS, Anwar MM, El-Hallouty SM.

Bioorg Med Chem · journal article · DOI 10.1016/j.bmc.2020.115657

Bibliografisk träff 2020-02-19

Designing Chimeric Molecules for Drug Discovery by Leveraging Chemical Biology.

Borsari C, Trader DJ, Tait A, Costi MP.

J Med Chem · research support, non-u.s. gov't; review-article; review; journal article · DOI 10.1021/acs.jmedchem.9b01456

Bibliografisk träff 2018-06-20

Discovery of Novel Topoisomerase II Inhibitors by Medicinal Chemistry Approaches.

Hu W, Huang XS, Wu JF, Yang L, Zheng YT, Shen YM, Li ZY, Li X.

J Med Chem · research support, non-u.s. gov't; review; journal article · DOI 10.1021/acs.jmedchem.7b01202

Bibliografisk träff 2016-03-03

DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.

Chen M, Suzuki A, Thakkar S, Yu K, Hu C, Tong W.

Drug Discov Today · review; journal article · DOI 10.1016/j.drudis.2016.02.015

Bibliografisk träff 2015-01-08

Interaction of human organic anion transporter polypeptides 1B1 and 1B3 with antineoplastic compounds.

Marada VV, Flörl S, Kühne A, Burckhardt G, Hagos Y.

Eur J Med Chem · research support, non-u.s. gov't; journal article · DOI 10.1016/j.ejmech.2015.01.011

Bibliografisk träff 2011-03-03

Bivalent bendamustine and melphalan derivatives as anticancer agents.

Scutaru AM, Wenzel M, Gust R.

Eur J Med Chem · research support, non-u.s. gov't; journal article · DOI 10.1016/j.ejmech.2011.02.008

Bibliografisk träff 2010-01-01

Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.

Fourches D, Barnes JC, Day NC, Bradley P, Reed JZ, Tropsha A.

Chem Res Toxicol · research-article; research support, u.s. gov't, non-p.h.s.; journal article; research support, n.i.h., extramural · DOI 10.1021/tx900326k

Bibliografisk träff 2008-10-04

Quantitative structure-activity relationship and complex network approach to monoamine oxidase A and B inhibitors.

Santana L, González-Díaz H, Quezada E, Uriarte E, Yáñez M, Viña D, Orallo F.

J Med Chem · research support, non-u.s. gov't; journal article · DOI 10.1021/jm800656v