PUBLICATION REGISTRY

Go to research.

Publikationsdata från Europe PMC och PubMed. Följ källhänvisningar från ämnesregistret till originalpublikationerna.

Publikationer som ChEBI hänvisar till för N-\{[3-(2-benzamido-4-methyl-1,3-thiazol-5-yl)-pyrazol-5-yl]carbonyl\}-G-dR-G-dD-dD-dD-NH2. Visa hela publikationsregistret

A publication hit is not a conclusion. Publikationslistan visar bibliografiska uppgifter. Eventuella forskningsutdrag visas separat med originalunderlag. En källhänvisning visar inte i sig effekt, dosering eller säkerhet.

Publications in the selection

22 hits

Bibliografisk träff 2017-07-04

Development of a series of novel 4-anlinoquinazoline derivatives possessing quinazoline skeleton: Design, synthesis, EGFR kinase inhibitory efficacy, and evaluation of anticancer activities in vitro.

Chang J, Ren H, Zhao M, Chong Y, Zhao W, He Y, Zhao Y, Zhang H, Qi C.

Eur J Med Chem · journal article · DOI 10.1016/j.ejmech.2017.07.005

Bibliografisk träff 2017-04-27

Compound 21 and Telmisartan combination mitigates type 2 diabetic nephropathy through amelioration of caspase mediated apoptosis.

Pandey A, Gaikwad AB.

Biochem Biophys Res Commun · journal article · DOI 10.1016/j.bbrc.2017.04.134

Bibliografisk träff 2017-03-01

Angiotensin II Type 2 Receptor Activation With Compound 21 Augments Islet Function and Regeneration in Streptozotocin-Induced Neonatal Rats and Human Pancreatic Progenitor Cells.

Wang L, Wang Y, Li XY, Leung PS.

Pancreas · research support, non-u.s. gov't; journal article · DOI 10.1097/mpa.0000000000000754

Bibliografisk träff 2017-02-10

Role of interleukin-10 in the neuroprotective effect of the Angiotensin Type 2 Receptor agonist, compound 21, after ischemia/reperfusion injury.

Fouda AY, Pillai B, Dhandapani KM, Ergul A, Fagan SC.

Eur J Pharmacol · research-article; journal article · DOI 10.1016/j.ejphar.2017.02.016

Bibliografisk träff 2016-05-11

The angiotensin II type 2 receptor agonist Compound 21 is protective in experimental diabetes-associated atherosclerosis.

Chow BS, Koulis C, Krishnaswamy P, Steckelings UM, Unger T, Cooper ME, Jandeleit-Dahm KA, Allen TJ.

Diabetologia · research support, non-u.s. gov't; journal article · DOI 10.1007/s00125-016-3977-5

Bibliografisk träff 2015-12-13

Central Infusion of Angiotensin II Type 2 Receptor Agonist Compound 21 Attenuates DOCA/NaCl-Induced Hypertension in Female Rats.

Dai SY, Zhang YP, Peng W, Shen Y, He JJ.

Oxid Med Cell Longev · research support, non-u.s. gov't; research-article; journal article · DOI 10.1155/2016/3981790

Bibliografisk träff 2015-06-29

Compound 21, a selective agonist of angiotensin AT2 receptors, prevents endothelial inflammation and leukocyte adhesion in vitro and in vivo.

Sampson AK, Irvine JC, Shihata WA, Dragoljevic D, Lumsden N, Huet O, Barnes T, Unger T, Steckelings UM, Jennings GL, Widdop RE, Chin-Dusting JP.

Br J Pharmacol · research support, non-u.s. gov't; research-article; journal article · DOI 10.1111/bph.13063

Bibliografisk träff 2015-03-16

AT2R agonist, compound 21, is reno-protective against type 1 diabetic nephropathy.

Koulis C, Chow BS, McKelvey M, Steckelings UM, Unger T, Thallas-Bonke V, Thomas MC, Cooper ME, Jandeleit-Dahm KA, Allen TJ.

Hypertension · research support, non-u.s. gov't; journal article · DOI 10.1161/hypertensionaha.115.05204

Bibliografisk träff 2015-01-24

Direct angiotensin II type 2 receptor stimulation by compound 21 prevents vascular dementia.

Iwanami J, Mogi M, Tsukuda K, Wang XL, Nakaoka H, Kan-no H, Chisaka T, Bai HY, Shan BS, Kukida M, Horiuchi M.

J Am Soc Hypertens · research support, non-u.s. gov't; journal article · DOI 10.1016/j.jash.2015.01.010

Bibliografisk träff 2015-01-01

Compound 21 is pro-angiogenic in the brain and results in sustained recovery after ischemic stroke.

Alhusban A, Fouda AY, Bindu Pillai, Ishrat T, Soliman S, Fagan SC.

J Hypertens · research support, non-u.s. gov't; research support, u.s. gov't, non-p.h.s.; journal article; research support, n.i.h., extramural · DOI 10.1097/hjh.0000000000000364

Bibliografisk träff 2014-11-14

Proinflammatory secreted phospholipase A2 type IIA (sPLA-IIA) induces integrin activation through direct binding to a newly identified binding site (site 2) in integrins αvβ3, α4β1, and α5β1.

Fujita M, Zhu K, Fujita CK, Zhao M, Lam KS, Kurth MJ, Takada YK, Takada Y.

J Biol Chem · research support, non-u.s. gov't; research-article; journal article; research support, n.i.h., extramural · DOI 10.1074/jbc.m114.579946

Bibliografisk träff 2014-09-03

Prevention of diabetic nephropathy by compound 21, selective agonist of angiotensin type 2 receptors, in Zucker diabetic fatty rats.

Castoldi G, di Gioia CR, Bombardi C, Maestroni S, Carletti R, Steckelings UM, Dahlöf B, Unger T, Zerbini G, Stella A.

Am J Physiol Renal Physiol · research support, non-u.s. gov't; journal article · DOI 10.1152/ajprenal.00247.2014

Bibliografisk träff 2014-07-01

Compound 21, a selective angiotensin II type 2 receptor agonist, downregulates lipopolysaccharide-stimulated tissue factor expression in human peripheral blood mononuclear cells.

Balia C, Petrini S, Scalise V, Neri T, Carnicelli V, Cianchetti S, Zucchi R, Celi A, Pedrinelli R.

Blood Coagul Fibrinolysis · research support, non-u.s. gov't; journal article · DOI 10.1097/mbc.0000000000000092

Bibliografisk träff 2014-04-21

Direct angiotensin AT2 receptor stimulation using a novel AT2 receptor agonist, compound 21, evokes neuroprotection in conscious hypertensive rats.

McCarthy CA, Vinh A, Miller AA, Hallberg A, Alterman M, Callaway JK, Widdop RE.

PLoS One · research support, non-u.s. gov't; research-article; journal article · DOI 10.1371/journal.pone.0095762

Bibliografisk träff 2014-03-31

Activation of central angiotensin type 2 receptors by compound 21 improves arterial baroreflex sensitivity in rats with heart failure.

Gao J, Zucker IH, Gao L.

Am J Hypertens · research-article; journal article; research support, n.i.h., extramural · DOI 10.1093/ajh/hpu044

Bibliografisk träff 2014-02-06

The angiotensin type 2 receptor agonist Compound 21 elicits cerebroprotection in endothelin-1 induced ischemic stroke.

Joseph JP, Mecca AP, Regenhardt RW, Bennion DM, Rodríguez V, Desland F, Patel NA, Pioquinto DJ, Unger T, Katovich MJ, Steckelings UM, Sumners C.

Neuropharmacology · research support, non-u.s. gov't; research-article; journal article; research support, n.i.h., extramural · DOI 10.1016/j.neuropharm.2014.01.044

Bibliografisk träff 2013-12-18

Possible synergistic effect of direct angiotensin II type 2 receptor stimulation by compound 21 with memantine on prevention of cognitive decline in type 2 diabetic mice.

Iwanami J, Mogi M, Tsukuda K, Jing F, Ohshima K, Wang XL, Nakaoka H, Kan-no H, Chisaka T, Bai HY, Min LJ, Horiuchi M.

Eur J Pharmacol · research support, non-u.s. gov't; journal article · DOI 10.1016/j.ejphar.2013.12.015

Bibliografisk träff 2013-09-16

Angiotensin II type 2 receptor-mediated and nitric oxide-dependent renal vasodilator response to compound 21 unmasked by angiotensin-converting enzyme inhibition in spontaneously hypertensive rats in vivo.

Brouwers S, Smolders I, Massie A, Dupont AG.

Hypertension · research support, non-u.s. gov't; journal article · DOI 10.1161/hypertensionaha.112.00762

Bibliografisk träff 2013-01-01

Protective effect of captopril, olmesartan, melatonin and compound 21 on doxorubicin-induced nephrotoxicity in rats.

Hrenák J, Arendášová K, Rajkovičová R, Aziriová S, Repová K, Krajčírovičová K, Celec P, Kamodyová N, Bárta A, Adamcová M, Paulis L, Simko F.

Physiol Res · comparative study; research support, non-u.s. gov't; journal article · DOI 10.33549/physiolres.932614

Bibliografisk träff 2012-10-24

Identification of inhibitors against interaction between pro-inflammatory sPLA2-IIA protein and integrin αvβ3.

Ye L, Dickerson T, Kaur H, Takada YK, Fujita M, Liu R, Knapp JM, Lam KS, Schore NE, Kurth MJ, Takada Y.

Bioorg Med Chem Lett · research support, non-u.s. gov't; research-article; research support, u.s. gov't, non-p.h.s.; journal article · DOI 10.1016/j.bmcl.2012.10.080

Bibliografisk träff 2012-07-16

Compound 21 induces vasorelaxation via an endothelium- and angiotensin II type 2 receptor-independent mechanism.

Verdonk K, Durik M, Abd-Alla N, Batenburg WW, van den Bogaerdt AJ, van Veghel R, Roks AJ, Danser AH, van Esch JH.

Hypertension · journal article · DOI 10.1161/hypertensionaha.112.196022

Bibliografisk träff 2011-12-19

Angiotensin type 2 receptor agonist compound 21 reduces vascular injury and myocardial fibrosis in stroke-prone spontaneously hypertensive rats.

Rehman A, Leibowitz A, Yamamoto N, Rautureau Y, Paradis P, Schiffrin EL.

Hypertension · research support, non-u.s. gov't; journal article · DOI 10.1161/hypertensionaha.111.180158