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Publikationsdata från Europe PMC och PubMed. Följ källhänvisningar från ämnesregistret till originalpublikationerna.

Publikationer som ChEBI hänvisar till för tipifarnib. Visa hela publikationsregistret

A publication hit is not a conclusion. Publikationslistan visar bibliografiska uppgifter. Eventuella forskningsutdrag visas separat med originalunderlag. En källhänvisning visar inte i sig effekt, dosering eller säkerhet.

Publications in the selection

12 hits

Bibliografisk träff 2018-05-14

Tipifarnib Inhibits HRAS-Driven Dedifferentiated Thyroid Cancers.

Untch BR, Dos Anjos V, Garcia-Rendueles MER, Knauf JA, Krishnamoorthy GP, Saqcena M, Bhanot UK, Socci ND, Ho AL, Ghossein R, Fagin JA.

Cancer Res · research support, non-u.s. gov't; research-article; journal article; research support, n.i.h., extramural · DOI 10.1158/0008-5472.can-17-1925

Bibliografisk träff 2018-01-27

A phase II study of tipifarnib and gemcitabine in metastatic breast cancer.

Yam C, Murthy RK, Valero V, Szklaruk J, Shroff GS, Stalzer CJ, Buzdar AU, Murray JL, Yang W, Hortobagyi GN, Moulder SL, Arun B.

Invest New Drugs · clinical trial, phase ii; journal article; research support, n.i.h., extramural · DOI 10.1007/s10637-018-0564-2

Bibliografisk träff 2017-10-07

Phase I study of sorafenib and tipifarnib for recurrent glioblastoma: NABTC 05-02.

Nghiemphu PL, Ebiana VA, Wen P, Gilbert M, Abrey LE, Lieberman F, DeAngelis LM, Robins HI, Yung WKA, Chang S, Drappatz J, Mehta MP, Levin VA, Aldape K, Dancey JE, Wright JJ, Prados M, Kuhn J, Cloughesy TF.

J Neurooncol · research-article; clinical trial, phase i; journal article · DOI 10.1007/s11060-017-2624-4

Bibliografisk träff 2017-03-01

Tipifarnib prevents development of hypoxia-induced pulmonary hypertension.

Duluc L, Ahmetaj-Shala B, Mitchell J, Abdul-Salam VB, Mahomed AS, Aldabbous L, Oliver E, Iannone L, Dubois OD, Storck EM, Tate EW, Zhao L, Wilkins MR, Wojciak-Stothard B.

Cardiovasc Res · research support, non-u.s. gov't; research-article; journal article · DOI 10.1093/cvr/cvw258

Bibliografisk träff 2015-08-25

Effect of Farnesyltransferase Inhibitor R115777 on Mitochondria of Plasmodium falciparum.

Ha YR, Hwang BG, Hong Y, Yang HW, Lee SJ.

Korean J Parasitol · research support, non-u.s. gov't; research-article; journal article · DOI 10.3347/kjp.2015.53.4.421

Bibliografisk träff 2014-02-04

Phase 2 randomized, flexible crossover, double-blinded, placebo-controlled trial of the farnesyltransferase inhibitor tipifarnib in children and young adults with neurofibromatosis type 1 and progressive plexiform neurofibromas.

Widemann BC, Dombi E, Gillespie A, Wolters PL, Belasco J, Goldman S, Korf BR, Solomon J, Martin S, Salzer W, Fox E, Patronas N, Kieran MW, Perentesis JP, Reddy A, Wright JJ, Kim A, Steinberg SM, Balis FM.

Neuro Oncol · clinical trial, phase ii; research support, n.i.h., intramural; research-article; randomized controlled trial; research support, u.s. gov't, non-p.h.s.; journal article · DOI 10.1093/neuonc/nou004

Bibliografisk träff 2013-04-22

Farnesyltransferase inhibitor R115777 protects against vascular disease in uremic mice.

Nikolov IG, Joki N, Galmiche A, Nguyen-Khoa T, Guerrera IC, Guillonneau F, Ivanovski O, Phan O, Maizel J, Marçon F, Benchitrit J, Lucas A, Edelman A, Lacour B, Drüeke TB, Massy ZA.

Atherosclerosis · research support, non-u.s. gov't; journal article · DOI 10.1016/j.atherosclerosis.2013.02.041

Bibliografisk träff 2011-12-31

Tipifarnib and tanespimycin show synergic proapoptotic activity in U937 cells.

Krzykowska-Petitjean K, Małecki J, Bentke A, Ostrowska B, Laidler P.

J Cancer Res Clin Oncol · brief-report; research support, non-u.s. gov't; journal article · DOI 10.1007/s00432-011-1131-9

Retracted publication 2006-08-02

Prevention of mouse lung tumors and modulation of DNA methylation by combined treatment with budesonide and R115777 (Zarnestra MT).

Alyaqoub FS, Tao L, Kramer PM, Steele VE, Lubet RA, Gunning WT, Pereira MA.

Carcinogenesis · retracted publication; research support, non-u.s. gov't; journal article; research support, n.i.h., extramural · DOI 10.1093/carcin/bgl136

Bibliografisk träff 2005-09-01

Biomarkers of anticancer activity of R115777 (Tipifarnib, Zarnestra) in human breast cancer models in vitro.

Izbicka E, Campos D, Carrizales G, Patnaik A.

Anticancer Res · journal article

Bibliografisk träff 2003-01-01

Farnesyl protein transferase inhibitor ZARNESTRA R115777 - history of a discovery.

Venet M, End D, Angibaud P.

Curr Top Med Chem · review; journal article · DOI 10.2174/1568026033452050

Bibliografisk träff 2002-07-01

Evaluation of accelerator mass spectrometry in a human mass balance and pharmacokinetic study-experience with 14C-labeled (R)-6-[amino(4- chlorophenyl)(1-methyl-1H-imidazol-5-yl)methyl]-4-(3-chlorophenyl)-1- methyl-2(1H)-quinolinone (R115777), a farnesyl transferase inhibitor.

Garner RC, Goris I, Laenen AA, Vanhoutte E, Meuldermans W, Gregory S, Garner JV, Leong D, Whattam M, Calam A, Snel CA.

Drug Metab Dispos · research support, non-u.s. gov't; evaluation study; journal article · DOI 10.1124/dmd.30.7.823