Evolution and function of carbohydrate reserve biosynthesis in parasitic protists.
Ralton JE, Sernee MF, McConville MJ.
Trends Parasitol · research support, non-u.s. gov't; review; journal article · DOI 10.1016/j.pt.2021.06.005 PUBLICATION REGISTRY
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10 hitsUntargeted metabolomics to understand the basis of phenotypic differences in amphotericin B-resistant <i>Leishmania</i> parasites.
Pountain AW, Barrett MP.
Wellcome Open Res · research-article; journal article · DOI 10.12688/wellcomeopenres.15452.1Mannogen-ing Central Carbon Metabolism by Leishmania.
Zhang K, Beverley SM.
Trends Parasitol · article-commentary; comment; journal article; research support, n.i.h., extramural · DOI 10.1016/j.pt.2019.10.001A Family of Dual-Activity Glycosyltransferase-Phosphorylases Mediates Mannogen Turnover and Virulence in Leishmania Parasites.
Sernee MF, Ralton JE, Nero TL, Sobala LF, Kloehn J, Vieira-Lara MA, Cobbold SA, Stanton L, Pires DEV, Hanssen E, Males A, Ward T, Bastidas LM, van der Peet PL, Parker MW, Ascher DB, Williams SJ, Davies GJ, McConville MJ.
Cell Host Microbe · journal article · DOI 10.1016/j.chom.2019.08.009Gluconeogenesis in Leishmania mexicana: contribution of glycerol kinase, phosphoenolpyruvate carboxykinase, and pyruvate phosphate dikinase.
Rodriguez-Contreras D, Hamilton N.
J Biol Chem · research support, non-u.s. gov't; research-article; journal article · DOI 10.1074/jbc.m114.569434Discovery of inhibitors of Leishmania β-1,2-mannosyltransferases using a click-chemistry-derived guanosine monophosphate library.
van der Peet P, Ralton JE, McConville MJ, Williams SJ.
PLoS One · research support, non-u.s. gov't; research-article; journal article · DOI 10.1371/journal.pone.0032642Isotopomer profiling of Leishmania mexicana promastigotes reveals important roles for succinate fermentation and aspartate uptake in tricarboxylic acid cycle (TCA) anaplerosis, glutamate synthesis, and growth.
Saunders EC, Ng WW, Chambers JM, Ng M, Naderer T, Krömer JO, Likic VA, McConville MJ.
J Biol Chem · research support, non-u.s. gov't; research-article; journal article · DOI 10.1074/jbc.m110.213553Use of click chemistry to define the substrate specificity of Leishmania beta-1,2-mannosyltransferases.
van der Peet P, Gannon CT, Walker I, Dinev Z, Angelin M, Tam S, Ralton JE, McConville MJ, Williams SJ.
Chembiochem · research support, non-u.s. gov't; journal article · DOI 10.1002/cbic.200600159Leishmania beta-1,2-mannan is assembled on a mannose-cyclic phosphate primer.
Sernee MF, Ralton JE, Dinev Z, Khairallah GN, O'Hair RA, Williams SJ, McConville MJ.
Proc Natl Acad Sci U S A · research support, non-u.s. gov't; research-article; journal article · DOI 10.1073/pnas.0603539103Evidence that intracellular beta1-2 mannan is a virulence factor in Leishmania parasites.
Ralton JE, Naderer T, Piraino HL, Bashtannyk TA, Callaghan JM, McConville MJ.
J Biol Chem · research support, non-u.s. gov't; journal article · DOI 10.1074/jbc.m307660200