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Publikationer som ChEBI hänvisar till för amrubicinol. Visa hela publikationsregistret

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Publications in the selection

19 hits

Bibliografisk träff 2019-10-03

Individual optimal dose of amrubicin to prevent severe neutropenia in Japanese patients with lung cancer.

Makino Y, Makihara-Ando R, Ogawa T, Sato H, Goto Y, Kanda S, Horinouchi H, Fujiwara Y, Ohe Y, Yamamoto N.

Cancer Sci · research-article; journal article · DOI 10.1111/cas.14194

Bibliografisk träff 2016-03-07

Simultaneous optimization of limited sampling points for pharmacokinetic analysis of amrubicin and amrubicinol in cancer patients.

Makino Y, Watanabe M, Makihara RA, Nokihara H, Yamamoto N, Ohe Y, Sugiyama E, Sato H, Hayashi Y.

Asia Pac J Clin Oncol · journal article · DOI 10.1111/ajco.12485

Bibliografisk träff 2013-02-12

Phase I study to assess the pharmacokinetics and the effect on cardiac repolarization of amrubicin and amrubicinol in patients with advanced solid tumors.

Chen N, Chawla SP, Chiorean EG, Read WL, Gorbaty M, Mita AC, Yung L, Bryan P, McNally R, Renschler MF, Sharma S.

Cancer Chemother Pharmacol · research support, non-u.s. gov't; multicenter study; clinical trial, phase i; journal article · DOI 10.1007/s00280-013-2093-1

Bibliografisk träff 2011-11-01

Pharmacokinetic and pharmacodynamic study on amrubicin and amrubicinol in Japanese patients with lung cancer.

Makino Y, Yamamoto N, Sato H, Ando R, Goto Y, Tanai C, Asahina H, Nokihara H, Sekine I, Kunitoh H, Ohe Y, Sugiyama E, Yokote N, Tamura T, Yamamoto H.

Cancer Chemother Pharmacol · research support, non-u.s. gov't; journal article · DOI 10.1007/s00280-011-1768-8

Bibliografisk träff 2010-12-03

Over-expression of MDR1 in amrubicinol-resistant lung cancer cells.

Takakuwa O, Oguri T, Ozasa H, Uemura T, Kasai D, Miyazaki M, Maeno K, Sato S.

Cancer Chemother Pharmacol · journal article · DOI 10.1007/s00280-010-1533-4

Bibliografisk träff 2010-03-01

Simple and sensitive HPLC method for determination of amrubicin and amrubicinol in human plasma: application to a clinical pharmacokinetic study.

Ando R, Makino Y, Tamura T, Yamamoto N, Nishigaki R, Kimura T, Yokote N, Yamamoto H.

Biomed Chromatogr · validation study; journal article · DOI 10.1002/bmc.1289

Bibliografisk träff 2009-08-21

Co-administration of irinotecan decreases the plasma concentration of an active metabolite of amrubicin, amrubicinol in rats.

Maeda Y, Hamada A, Sanematsu E, Sasaki JI, Yokoo K, Hira A, Saito H.

Cancer Chemother Pharmacol · research support, non-u.s. gov't; journal article · DOI 10.1007/s00280-009-1102-x

Bibliografisk träff 2009-07-01

Plasma concentration of amrubicinol in plateau phase in patients treated for 3 days with amrubicin is correlated with hematological toxicities.

Kimura T, Kudoh S, Mitsuoka S, Yoshimura N, Tanaka H, Asai K, Kyoh S, Tochino Y, Umekawa K, Hirata K.

Anticancer Drugs · clinical trial, phase ii; research support, non-u.s. gov't; clinical trial, phase i; journal article · DOI 10.1097/cad.0b013e32832b0585

Bibliografisk träff 2008-04-12

Pulse gradient, large-volume injection, high-throughput ultra-performance liquid chromatographic/tandem mass spectrometry bioanalysis for measurement of plasma amrubicin and its metabolite amrubicinol.

Li Y, Sun Y, Du F, Yuan K, Li C.

J Chromatogr A · research support, non-u.s. gov't; validation study; journal article · DOI 10.1016/j.chroma.2008.04.014

Bibliografisk träff 2007-10-30

Role of P-glycoprotein in accumulation and cytotoxicity of amrubicin and amrubicinol in MDR1 gene-transfected LLC-PK1 cells and human A549 lung adenocarcinoma cells.

Hira A, Watanabe H, Maeda Y, Yokoo K, Sanematsu E, Fujii J, Sasaki J, Hamada A, Saito H.

Biochem Pharmacol · research support, non-u.s. gov't; journal article · DOI 10.1016/j.bcp.2007.10.023

Bibliografisk träff 2006-11-01

Enhancement of radiosensitivity by topoisomerase II inhibitor, amrubicin and amrubicinol, in human lung adenocarcinoma A549 cells and kinetics of apoptosis and necrosis induction.

Hayashi S, Hatashita M, Matsumoto H, Shioura H, Kitai R, Kano E.

Int J Mol Med · research support, non-u.s. gov't; journal article · DOI 10.3892/ijmm.18.5.909

Bibliografisk träff 2006-09-21

Amrubicin induces apoptosis in human tumor cells mediated by the activation of caspase-3/7 preceding a loss of mitochondrial membrane potential.

Hanada M, Noguchi T, Yamaoka T.

Cancer Sci · research-article; journal article · DOI 10.1111/j.1349-7006.2006.00318.x

Bibliografisk träff 2006-04-01

The combination effect of amrubicin with cisplatin or irinotecan for small-cell lung cancer cells.

Takigawa N, Takeyama M, Shibayama T, Tada A, Kawata N, Okada C, Aoe K, Kozuki T, Hotta K, Tabata M, Kiura K, Ueoka H, Tanimoto M, Takahashi K.

Oncol Rep · journal article · DOI 10.3892/or.15.4.837

Bibliografisk träff 2006-02-01

Pharmacokinetics of amrubicin and its active metabolite amrubicinol in lung cancer patients.

Matsunaga Y, Hamada A, Okamoto I, Sasaki J, Moriyama E, Kishi H, Matsumoto M, Hira A, Watanabe H, Saito H.

Ther Drug Monit · clinical trial; research support, non-u.s. gov't; journal article · DOI 10.1097/01.ftd.0000185771.82620.ee

Bibliografisk träff 2005-12-01

Characterization of the enzymes involved in the in vitro metabolism of amrubicin hydrochloride.

Tani N, Yabuki M, Komuro S, Kanamaru H.

Xenobiotica · journal article · DOI 10.1080/00498250500342746

Bibliografisk träff 2005-09-01

Modification of thermosensitivity by amrubicin or amrubicinol in human lung adenocarcinoma A549 cells and the kinetics of apoptosis and necrosis induction.

Hayashi S, Hatashita M, Matsumoto H, Jin ZH, Shioura H, Kano E.

Int J Mol Med · comparative study; research support, non-u.s. gov't; journal article · DOI 10.3892/ijmm.16.3.381

Bibliografisk träff 2002-06-01

Additive effects of amrubicin with cisplatin on human lung cancer cell lines.

Yamauchi S, Kudoh S, Kimura T, Hirata K, Yoshikawa J.

Osaka City Med J · journal article

Bibliografisk träff 1999-06-01

Uptake and intracellular distribution of amrubicin, a novel 9-amino-anthracycline, and its active metabolite amrubicinol in P388 murine leukemia cells.

Yamaoka T, Hanada M, Ichii S, Morisada S, Noguchi T, Yanagi Y.

Jpn J Cancer Res · research-article; journal article · DOI 10.1111/j.1349-7006.1999.tb00801.x

Bibliografisk träff 1998-10-01

Cytotoxicity of amrubicin, a novel 9-aminoanthracycline, and its active metabolite amrubicinol on human tumor cells.

Yamaoka T, Hanada M, Ichii S, Morisada S, Noguchi T, Yanagi Y.

Jpn J Cancer Res · research-article; journal article · DOI 10.1111/j.1349-7006.1998.tb00498.x