Insight into enzyme-catalyzed aziridine formation mechanism in ficellomycin biosynthesis.
Yue R, Li M, Wang Y, Guan Y, Zhang J, Yan Z, Liu F, Lu F, Zhang H.
Eur J Med Chem · journal article · DOI 10.1016/j.ejmech.2020.112639 PUBLICATION REGISTRY
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8 hitsGuanidyl modification of the 1-azabicyclo[3.1.0]hexane ring in ficellomycin essential for its biological activity.
Kurosawa S, Matsuda K, Hasebe F, Shiraishi T, Shin-Ya K, Kuzuyama T, Nishiyama M.
Org Biomol Chem · research support, non-u.s. gov't; journal article · DOI 10.1039/d0ob00339eFicellomycin: an aziridine alkaloid antibiotic with potential therapeutic capacity.
He X, Li M, Song S, Wu X, Zhang J, Wu G, Yue R, Cui H, Song S, Ma C, Lu F, Zhang H.
Appl Microbiol Biotechnol · review; journal article · DOI 10.1007/s00253-018-8934-4Identification and characterization of the ficellomycin biosynthesis gene cluster from Streptomyces ficellus.
Liu Y, Li M, Mu H, Song S, Zhang Y, Chen K, He X, Wang H, Dai Y, Lu F, Yan Z, Zhang H.
Appl Microbiol Biotechnol · journal article · DOI 10.1007/s00253-017-8465-4Mode of action and biosynthesis of the azabicycle-containing natural products azinomycin and ficellomycin.
Foulke-Abel J, Agbo H, Zhang H, Mori S, Watanabe CM.
Nat Prod Rep · research support, non-u.s. gov't; review; journal article · DOI 10.1039/c0np00049cStructure elucidation of ficellomycin.
Kuo MS, Yurek DA, Mizsak SA.
J Antibiot (Tokyo) · journal article · DOI 10.7164/antibiotics.42.357Ficellomycin and feldamycin; inhibitors of bacterial semiconservative DNA replication.
Reusser F.
Biochemistry · journal article · DOI 10.1021/bi00634a018Antibiotics produced by Streptomyces ficellus. I. Ficellomycin.
Argoudelis AD, Reusser F, Whaley HA, Baczynskyj L, Mizsak SA, Wnuk RJ.
J Antibiot (Tokyo) · journal article · DOI 10.7164/antibiotics.29.1001