Total and Formal Syntheses of Fostriecin.
Dong G, Li B, O'Doherty G.
Org Chem Front · research-article; journal article · DOI 10.1039/d0qo01121e PUBLICATION REGISTRY
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18 hitsSynthesis of Dehydro-Dephospho-Fostriecin and Formal Total Synthesis of Fostriecin.
Gao D, Li B, O'Doherty GA.
Org Lett · research support, u.s. gov't, non-p.h.s.; journal article; research support, n.i.h., extramural · DOI 10.1021/acs.orglett.9b03120Effects of fostriecin on β2-adrenoceptor-driven responses in human mast cells.
Bastan R, Eskandari N, J Ardakani H, T Peachell P.
J Immunotoxicol · journal article · DOI 10.1080/1547691x.2016.1259277Synthetic Strategies Employed for the Construction of Fostriecin and Related Natural Products.
Trost BM, Knopf JD, Brindle CS.
Chem Rev · research-article; review; journal article · DOI 10.1021/acs.chemrev.6b00488Suppression of Ser/Thr phosphatase 4 (PP4C/PPP4C) mimics a novel post-mitotic action of fostriecin, producing mitotic slippage followed by tetraploid cell death.
Theobald B, Bonness K, Musiyenko A, Andrews JF, Urban G, Huang X, Dean NM, Honkanen RE.
Mol Cancer Res · research support, non-u.s. gov't; research-article; research support, u.s. gov't, non-p.h.s.; journal article; research support, n.i.h., extramural · DOI 10.1158/1541-7786.mcr-13-0032Identification of the post-polyketide synthase modification enzymes for fostriecin biosynthesis in Streptomyces pulveraceus.
Liu XJ, Kong RX, Niu MS, Qiu RG, Tang L.
J Nat Prod · research support, non-u.s. gov't; journal article · DOI 10.1021/np300667rElucidation of the biosynthetic gene cluster and the post-PKS modification mechanism for fostriecin in Streptomyces pulveraceus.
Kong R, Liu X, Su C, Ma C, Qiu R, Tang L.
Chem Biol · research support, non-u.s. gov't; journal article · DOI 10.1016/j.chembiol.2012.10.018Formal total synthesis of fostriecin by 1,4-asymmetric induction with an alkyne-cobalt complex.
Hayashi Y, Yamaguchi H, Toyoshima M, Okado K, Toyo T, Shoji M.
Chemistry · research support, non-u.s. gov't; journal article · DOI 10.1002/chem.201000795Total synthesis of fostriecin: via a regio- and stereoselective polyene hydration, oxidation, and hydroboration sequence.
Gao D, O'Doherty GA.
Org Lett · research-article; research support, u.s. gov't, non-p.h.s.; journal article; research support, n.i.h., extramural · DOI 10.1021/ol101340nConvergent synthesis of fostriecin via selective alkene couplings and regioselective asymmetric dihydroxylation.
Robles O, McDonald FE.
Org Lett · journal article · DOI 10.1021/ol902365nStructure-activity relationship studies of fostriecin, cytostatin, and key analogs, with PP1, PP2A, PP5, and( beta12-beta13)-chimeras (PP1/PP2A and PP5/PP2A), provide further insight into the inhibitory actions of fostriecin family inhibitors.
Swingle MR, Amable L, Lawhorn BG, Buck SB, Burke CP, Ratti P, Fischer KL, Boger DL, Honkanen RE.
J Pharmacol Exp Ther · comparative study; research-article; journal article; research support, n.i.h., extramural · DOI 10.1124/jpet.109.155630Catalyst-controlled asymmetric synthesis of fostriecin and 8-epi-fostriecin.
Maki K, Motoki R, Fujii K, Kanai M, Kobayashi T, Tamura S, Shibasaki M.
J Am Chem Soc · research support, non-u.s. gov't; journal article · DOI 10.1021/ja0562043Total synthesis of an antitumor antibiotic, Fostriecin (CI-920).
Miyashita K, Ikejiri M, Kawasaki H, Maemura S, Imanishi T.
J Am Chem Soc · journal article · DOI 10.1021/ja030133vFormal total synthesis of fostriecin.
Wang YG, Kobayashi Y.
Org Lett · journal article · DOI 10.1021/ol020193qFostriecin: chemistry and biology.
Lewy DS, Gauss CM, Soenen DR, Boger DL.
Curr Med Chem · research support, u.s. gov't, p.h.s.; research support, non-u.s. gov't; review; journal article · DOI 10.2174/0929867023368809Total synthesis of fostriecin (CI-920) via a convergent route.
Miyashita K, Ikejiri M, Kawasaki H, Maemura S, Imanishi T.
Chem Commun (Camb) · journal article · DOI 10.1039/b201302aTotal synthesis of fostriecin (CI-920).
Boger DL, Ichikawa S, Zhong W.
J Am Chem Soc · research support, u.s. gov't, p.h.s.; research support, non-u.s. gov't; journal article · DOI 10.1021/ja010195qFostriecin, an inhibitor of protein phosphatase 2A, limits myocardial infarct size even when administered after onset of ischemia.
Weinbrenner C, Baines CP, Liu GS, Armstrong SC, Ganote CE, Walsh AH, Honkanen RE, Cohen MV, Downey JM.
Circulation · research support, u.s. gov't, p.h.s.; research support, non-u.s. gov't; journal article · DOI 10.1161/01.cir.98.9.899