In vitro melanin binding of NS-49, a phenethylamine class alpha 1A-adrenoceptor agonist.
Yamada T, Okuyama Y, Mukai H.
Arzneimittelforschung · journal article · DOI 10.1055/s-0031-1300041 PUBLICATION REGISTRY
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14 hitsPharmacokinetics of NS-49, a phenethylamine class alpha 1A-adrenoceptor agonist. 4th communication: tissue distribution, placental transfer and milk secretion of radioactivity in rats after a single oral administration of 14C-NS-49, and effects of repeated administration on its pharmacokinetics.
Dalrymple PD, Beeby TL, Mukai H, Chasseaud LF.
Arzneimittelforschung · journal article · DOI 10.1055/s-0031-1300053Tissue distribution of NS-49, a phenethylamine class alpha 1A-adrenoceptor agonist, in pigmented rats.
Koike T, Kitazumi H, Mukai H.
Arzneimittelforschung · journal article · DOI 10.1055/s-0031-1300054alpha(1)-adrenoceptor subtypes and effect of alpha(1A)-adrenoceptor agonist NS-49 on guinea pig nasal mucosa vasculature.
Tanimitsu N, Yajin K, Sasa M, Tsuru H.
Eur J Pharmacol · journal article · DOI 10.1016/s0014-2999(99)00783-9Contractile responses to alpha1-adrenoceptor agonists in isolated human male and female urethra.
Nishimatsu H, Moriyama N, Hamada K, Ukai Y, Yamazaki S, Kameyama S, Konno N, Ishida Y, Ishii Y, Murayama T, Kitamura T.
BJU Int · research support, non-u.s. gov't; journal article · DOI 10.1046/j.1464-410x.1999.00218.xPharmacokinetics of NS-49, a phenethylamine class alpha(1A)-adrenoceptor agonist, at therapeutic doses in several animal species and interspecies scaling of its pharmacokinetic parameters.
Mukai H, Watanabe S, Tsuchida K, Morino A.
Int J Pharm · comparative study; journal article · DOI 10.1016/s0378-5173(99)00184-2Effects of renal insufficiency and aging on the pharmacokinetics of a phenethylamine class alpha(1A)-adrenoceptor agonist NS-49.
Mukai H, Morino A.
Int J Pharm · journal article · DOI 10.1016/s0378-5173(99)00142-8Pharmacokinetics of NS-49, a phenethylamine class alpha 1A-adrenoceptor agonist. 3rd communication: metabolism in rats, rabbits, dogs and monkeys, and effects on hepatic drug-metabolizing enzyme activities in rats after repeated administration.
Mukai H, Watanabe S, Morino A.
Arzneimittelforschung · comparative study; journal article · DOI 10.1055/s-0031-1300471Pharmacokinetics of NS-49, a phenethylamine class alpha 1A-adrenoceptor agonist. 2nd communication: Absorption and excretion in rabbits, dogs and monkeys after a single administration of 14C-NS-49.
Mukai H, Watanabe S, Morino A.
Arzneimittelforschung · comparative study; journal article · DOI 10.1055/s-0031-1300455Pharmacokinetics of NS-49, a phenethylamine class alpha 1A-adrenoceptor agonist. 1st communication: absorption and excretion in rats after a single administration of 14C-NS-49.
Mukai H, Watanabe S, Morino A.
Arzneimittelforschung · journal article · DOI 10.1055/s-0031-1300439Renal excretion mechanism of NS-49, a phenethylamine class alpha 1A-adrenoceptor agonist.
Mukai H, Morino A.
Biopharm Drug Dispos · journal article · DOI 10.1002/(sici)1099-081x(199905)20:4<207::aid-bdd175>3.0.co;2-dNS-49, an alpha 1A-adrenoceptor agonist, selectively increases intraurethral pressure in dogs.
Taniguchi N, Hamada K, Ogasawara T, Ukai Y, Yoshikuni Y, Kimura K.
Eur J Pharmacol · comparative study; journal article · DOI 10.1016/s0014-2999(96)00766-2NS-49, a novel alpha 1a-adrenoceptor-selective agonist characterization using recombinant human alpha 1-adrenoceptors.
Obika K, Shibata K, Horie K, Foglar R, Kimura K, Tsujimoto G.
Eur J Pharmacol · comparative study; research support, non-u.s. gov't; journal article · DOI 10.1016/0922-4106(95)90073-xPharmacological profiles of a novel alpha 1-adrenoceptor agonist, PNO-49B, at alpha 1-adrenoceptor subtypes.
Muramatsu I, Ohmura T, Kigoshi S.
Naunyn Schmiedebergs Arch Pharmacol · research support, non-u.s. gov't; journal article · DOI 10.1007/bf00169057