A Bioassay Using a Pentadecanal Derivative to Measure S1P Lyase Activity.
Shin KO, Shamshiddinova M, Lee JN, Lee KS, Lee YM.
Int J Mol Sci · research-article; journal article · DOI 10.3390/ijms22031438 PUBLICATION REGISTRY
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16 hitsExogenous dihydrosphingosine 1 phosphate mediates collagen synthesis in cardiac fibroblasts through JAK/STAT signalling and regulation of TIMP1.
Magaye RR, Savira F, Hua Y, Xiong X, Huang L, Reid C, Flynn B, Kaye D, Liew D, Wang BH.
Cell Signal · research support, non-u.s. gov't; journal article · DOI 10.1016/j.cellsig.2020.109629Diurnal regulation of sphingolipids in blood.
Brunkhorst R, Pfeilschifter W, Rajkovic N, Pfeffer M, Fischer C, Korf HW, Christoffersen C, Trautmann S, Thomas D, Pfeilschifter J, Koch A.
Biochim Biophys Acta Mol Cell Biol Lipids · research support, non-u.s. gov't; journal article · DOI 10.1016/j.bbalip.2018.12.001Scintillation Proximity Assay to Detect the Changes in Cellular Dihydrosphingosine 1-Phosphate Levels.
Ohtoyo M, Tamura M, Machinaga N, Muro F, Hashimoto R.
Lipids · journal article · DOI 10.1007/s11745-016-4187-0PhotoImmunoNanoTherapy reveals an anticancer role for sphingosine kinase 2 and dihydrosphingosine-1-phosphate.
Barth BM, Shanmugavelandy SS, Kaiser JM, McGovern C, Altınoğlu Eİ, Haakenson JK, Hengst JA, Gilius EL, Knupp SA, Fox TE, Smith JP, Ritty TM, Adair JH, Kester M.
ACS Nano · research support, non-u.s. gov't; research-article; journal article; research support, n.i.h., extramural · DOI 10.1021/nn304862bDistinct generation, pharmacology, and distribution of sphingosine 1-phosphate and dihydrosphingosine 1-phosphate in human neural progenitor cells.
Callihan P, Zitomer NC, Stoeling MV, Kennedy PC, Lynch KR, Riley RT, Hooks SB.
Neuropharmacology · research support, non-u.s. gov't; research-article; journal article; research support, n.i.h., extramural · DOI 10.1016/j.neuropharm.2011.10.005Dihydrosphingosine 1-phosphate has a potent antifibrotic effect in scleroderma fibroblasts via normalization of phosphatase and tensin homolog levels.
Bu S, Asano Y, Bujor A, Highland K, Hant F, Trojanowska M.
Arthritis Rheum · research-article; journal article; research support, n.i.h., extramural · DOI 10.1002/art.27463FTY720 inhibits ceramide synthases and up-regulates dihydrosphingosine 1-phosphate formation in human lung endothelial cells.
Berdyshev EV, Gorshkova I, Skobeleva A, Bittman R, Lu X, Dudek SM, Mirzapoiazova T, Garcia JG, Natarajan V.
J Biol Chem · research support, non-u.s. gov't; research-article; journal article; research support, n.i.h., extramural · DOI 10.1074/jbc.m805186200Opposite effects of dihydrosphingosine 1-phosphate and sphingosine 1-phosphate on transforming growth factor-beta/Smad signaling are mediated through the PTEN/PPM1A-dependent pathway.
Bu S, Kapanadze B, Hsu T, Trojanowska M.
J Biol Chem · research-article; journal article; research support, n.i.h., extramural · DOI 10.1074/jbc.m802417200Elevation of sphinganine 1-phosphate as a predictive biomarker for fumonisin exposure and toxicity in mice.
Kim DH, Yoo HS, Lee YM, Kie JH, Jang S, Oh S.
J Toxicol Environ Health A · research support, non-u.s. gov't; journal article · DOI 10.1080/15287390600746215De novo biosynthesis of dihydrosphingosine-1-phosphate by sphingosine kinase 1 in mammalian cells.
Berdyshev EV, Gorshkova IA, Usatyuk P, Zhao Y, Saatian B, Hubbard W, Natarajan V.
Cell Signal · journal article; research support, n.i.h., extramural · DOI 10.1016/j.cellsig.2006.01.018Dihydrosphingosine 1-phosphate stimulates MMP1 gene expression via activation of ERK1/2-Ets1 pathway in human fibroblasts.
Bu S, Yamanaka M, Pei H, Bielawska A, Bielawski J, Hannun YA, Obeid L, Trojanowska M.
FASEB J · journal article; research support, n.i.h., extramural · DOI 10.1096/fj.05-4646fjeIdentification and characterization of Saccharomyces cerevisiae dihydrosphingosine-1-phosphate phosphatase.
Mao C, Wadleigh M, Jenkins GM, Hannun YA, Obeid LM.
J Biol Chem · research support, u.s. gov't, p.h.s.; research support, non-u.s. gov't; journal article · DOI 10.1074/jbc.272.45.28690Synthesis of sphingosine-1-phosphate and dihydrosphingosine-1-phosphate.
Boumendjel A, Miller SP.
J Lipid Res · journal article · DOI 10.1016/s0022-2275(20)39936-3Sphinganine 1-phosphate metabolism in cultured skin fibroblasts: evidence for the existence of a sphingosine phosphatase.
Van Veldhoven PP, Mannaerts GP.
Biochem J · research support, non-u.s. gov't; research-article; journal article · DOI 10.1042/bj2990597A facile enzymatic synthesis of sphingosine-1-phosphate and dihydrosphingosine-1-phosphate.
Van Veldhoven PP, Foglesong RJ, Bell RM.
J Lipid Res · research support, u.s. gov't, p.h.s.; journal article · DOI 10.1016/s0022-2275(20)38352-8