Neo-epitopes on methylglyoxal modified human serum albumin lead to aggressive autoimmune response in diabetes.
Jyoti, Mir AR, Habib S, Siddiqui SS, Ali A, Moinuddin.
Int J Biol Macromol · journal article · DOI 10.1016/j.ijbiomac.2016.02.019 PUBLICATION REGISTRY
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Publikationer som ChEBI hänvisar till för methylglyoxal. Visa hela publikationsregistret
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14 hitsArginine modifications by methylglyoxal: discovery in a recombinant monoclonal antibody and contribution to acidic species.
Chumsae C, Gifford K, Lian W, Liu H, Radziejewski CH, Zhou ZS.
Anal Chem · research support, non-u.s. gov't; research-article; journal article; research support, n.i.h., extramural · DOI 10.1021/ac402384yIncreased methylglyoxal formation with upregulation of renin angiotensin system in fructose fed Sprague Dawley rats.
Dhar I, Dhar A, Wu L, Desai KM.
PLoS One · research support, non-u.s. gov't; research-article; journal article · DOI 10.1371/journal.pone.0074212Methylglyoxal further impairs adipose tissue metabolism after partial decrease of blood supply.
Rodrigues T, Matafome P, Seiça R.
Arch Physiol Biochem · research support, non-u.s. gov't; journal article · DOI 10.3109/13813455.2013.812121Multispecificity of immunoglobulin M antibodies raised against advanced glycation end products: involvement of electronegative potential of antigens.
Chikazawa M, Otaki N, Shibata T, Miyashita H, Kawai Y, Maruyama S, Toyokuni S, Kitaura Y, Matsuda T, Uchida K.
J Biol Chem · research support, non-u.s. gov't; research-article; journal article · DOI 10.1074/jbc.m113.452177Methylglyoxal, obesity, and diabetes.
Matafome P, Sena C, Seiça R.
Endocrine · review; journal article · DOI 10.1007/s12020-012-9795-8Methylglyoxal has injurious effects on maturation of mouse oocytes, fertilization, and fetal development, via apoptosis.
Chang YJ, Chan WH.
Toxicol Lett · research support, non-u.s. gov't; journal article · DOI 10.1016/j.toxlet.2010.01.007Methylglyoxal inhibits smooth muscle contraction in isolated blood vessels.
Mukohda M, Yamawaki H, Nomura H, Okada M, Hara Y.
J Pharmacol Sci · research support, non-u.s. gov't; journal article · DOI 10.1254/jphs.08300fpMethylglyoxal in food and living organisms.
Nemet I, Varga-Defterdarović L, Turk Z.
Mol Nutr Food Res · research support, non-u.s. gov't; review; journal article · DOI 10.1002/mnfr.200600065Methylglyoxal, a metabolite derived from glycolysis, functions as a signal initiator of the high osmolarity glycerol-mitogen-activated protein kinase cascade and calcineurin/Crz1-mediated pathway in Saccharomyces cerevisiae.
Maeta K, Izawa S, Inoue Y.
J Biol Chem · research support, non-u.s. gov't; journal article · DOI 10.1074/jbc.m408061200Methylglyoxal, an endogenous aldehyde, crosslinks DNA polymerase and the substrate DNA.
Murata-Kamiya N, Kamiya H.
Nucleic Acids Res · research support, non-u.s. gov't; research-article; journal article · DOI 10.1093/nar/29.16.3433Methylglyoxal induces apoptosis in Jurkat leukemia T cells by activating c-Jun N-terminal kinase.
Du J, Suzuki H, Nagase F, Akhand AA, Yokoyama T, Miyata T, Kurokawa K, Nakashima I.
J Cell Biochem · research support, non-u.s. gov't; journal article · DOI 10.1002/(sici)1097-4644(20000501)77:2<333::aid-jcb15>3.0.co;2-qMethylglyoxal modification of protein. Chemical and immunochemical characterization of methylglyoxal-arginine adducts.
Oya T, Hattori N, Mizuno Y, Miyata S, Maeda S, Osawa T, Uchida K.
J Biol Chem · research support, non-u.s. gov't; journal article · DOI 10.1074/jbc.274.26.18492Immunological evidence for methylglyoxal-derived modifications in vivo. Determination of antigenic epitopes.
Shamsi FA, Partal A, Sady C, Glomb MA, Nagaraj RH.
J Biol Chem · research support, u.s. gov't, p.h.s.; research support, non-u.s. gov't; journal article · DOI 10.1074/jbc.273.12.6928